{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:31:00Z","timestamp":1767349860115,"version":"3.48.0"},"reference-count":11,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Gelatin-based hemostatic agents are widely used in neurosurgery due to their effectiveness and general biocompatibility. However, rare adverse events such as foreign body granuloma (FBG) formation can occur.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n \n Here, we report the case of a 52-year-old male who developed progressive neurological symptoms compatible with myelopathy following cervical decompression surgery in which Gelfoam\n \u00ae<\/jats:sup>\n was applied. A FBG was found on imaging and confirmed following surgical excision.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This case highlights the importance of including FBG in the differential diagnosis of postoperative neurological deterioration whenever gelatin-based hemostatic agents are used.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_1054_2025","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T12:10:17Z","timestamp":1766146217000},"page":"543","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute myelopathy caused by granuloma formation secondary to gelatin sponge: A case report of a rare complication"],"prefix":"10.25259","volume":"16","author":[{"given":"Hector R.","family":"Martinez","sequence":"first","affiliation":[{"name":"Department of Neurology and Neurosurgery, Zambrano Hellion Medical Center, San Pedro Garza Garcia, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Gutierrez-Trevino","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, Zambrano Hellion Medical Center, San Pedro Garza Garcia, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Gomez-Guerra","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey, School of Medicine and Health Sciences, Monterrey, Nuevo Leon, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristopher J.","family":"Nivela-Due\u00f1as","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey, School of Medicine and Health Sciences, Monterrey, Nuevo Leon, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco A.","family":"Rodriguez-Leal","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, Zambrano Hellion Medical Center, San Pedro Garza Garcia, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose A.","family":"Figueroa-Sanchez","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, Zambrano Hellion Medical Center, San Pedro Garza Garcia, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"10.25259\/SNI_1054_2025\/ref-1","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1111\/vsu.12551","article-title":"Magnetic resonance imaging appearance and mechanism of action of five hemostatic agents used in neurosurgery","volume":"45","author":"Brundage","year":"2016","journal-title":"Vet Surg"},{"key":"10.25259\/SNI_1054_2025\/ref-2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1159\/000319397","article-title":"Foreign body granuloma mimicking upper cervical spinal mass after Dural repair with tachocomb [correction of tachocomp]: A case report","volume":"46","author":"Ekici","year":"2010","journal-title":"Pediatr Neurosurg"},{"key":"10.25259\/SNI_1054_2025\/ref-3","doi-asserted-by":"crossref","first-page":"e19","DOI":"10.1016\/j.spinee.2008.03.009","article-title":"Increased postoperative cervical myelopathy and cord compression resulting from the use of Gelfoam","volume":"9","author":"Epstein","year":"2009","journal-title":"Spine J"},{"key":"10.25259\/SNI_1054_2025\/ref-4","doi-asserted-by":"crossref","first-page":"S301","DOI":"10.4103\/2152-7806.111427","article-title":"A review article on the diagnosis and treatment of cerebrospinal fluid fistulas and Dural tears occurring during spinal surgery","volume":"4","author":"Epstein","year":"2013","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_1054_2025\/ref-5","first-page":"760","article-title":"The CARE guidelines: Consensus-based clinical case reporting guideline development","volume":"66","author":"Gagnier","year":"2013","journal-title":"J Clin Epidemiol"},{"key":"10.25259\/SNI_1054_2025\/ref-6","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1136\/jnnp.37.8.971","article-title":"Gel-foam granuloma in the brain","volume":"37","author":"Knowlson","year":"1974","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.25259\/SNI_1054_2025\/ref-7","first-page":"3996","article-title":"Intracranial foreign body granuloma caused by gelatin sponge: A case report and literature review","volume":"10","author":"Lei","year":"2017","journal-title":"Int J Clin Exp Med"},{"key":"10.25259\/SNI_1054_2025\/ref-8","doi-asserted-by":"crossref","first-page":"e1900","DOI":"10.1590\/0100-6991e-20181900","article-title":"Topical hemostatic agents in surgery: Review and prospects [Agentes hemost\u00e1ticos t\u00f3picos em cirurgia: Revis\u00e3o e perspectivas]","volume":"45","author":"Pereira","year":"2018","journal-title":"Rev Col Bras Cir"},{"key":"10.25259\/SNI_1054_2025\/ref-9","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s10143-021-01684-1","article-title":"Topical hemostatic agents in neurosurgery, a comprehensive review: 15 years update","volume":"45","author":"Schonauer","year":"2022","journal-title":"Neurosurg Rev"},{"key":"10.25259\/SNI_1054_2025\/ref-10","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S1008-1275(08)60027-9","article-title":"Delayed myelopathy after stab injury with intraspinal nonmetal foreign body granuloma","volume":"11","author":"WU","year":"2008","journal-title":"Chin J Traumatol"},{"key":"10.25259\/SNI_1054_2025\/ref-11","doi-asserted-by":"crossref","first-page":"903","DOI":"10.14245\/ns.2142112.056","article-title":"Upper cervical compression myelopathy caused by the retroodontoid pseudotumor with degenerative osteoarthritis and calcium pyrophosphate dihydrate disease: A case report and literature review","volume":"18","author":"Yurube","year":"2021","journal-title":"Neurospine"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/acute-myelopathy-caused-by-granuloma-formation-secondary-to-gelatin-sponge-a-case-report-of-a-rare-complication\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/acute-myelopathy-caused-by-granuloma-formation-secondary-to-gelatin-sponge-a-case-report-of-a-rare-complication\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:28:10Z","timestamp":1767349690000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/acute-myelopathy-caused-by-granuloma-formation-secondary-to-gelatin-sponge-a-case-report-of-a-rare-complication\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":11,"alternative-id":["10.25259\/SNI_1054_2025"],"URL":"https:\/\/doi.org\/10.25259\/sni_1054_2025","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"type":"electronic","value":"2152-7806"},{"type":"print","value":"2229-5097"}],"subject":[],"published":{"date-parts":[[2025,12,19]]},"article-number":"543"}}