{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:55:41Z","timestamp":1777510541642,"version":"3.51.4"},"reference-count":27,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nPresurgical three-dimensional (3D) reconstructions allow spatial localization of cerebral lesions and their relationship with adjacent anatomical structures for optimal surgical resolution. The purpose of the present article is to present a method of virtual preoperative planning aiming to enhance 3D comprehension of neurosurgical pathologies using free DICOM image viewers.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nWe describe the virtual presurgical planning of a 61-year-old female presenting a cerebral tumor. 3D reconstructions were created with the \u201cHoros\u00ae<\/jats:sup>\u201d Digital Imaging and Communications in Medicine viewer, utilizing images obtained from contrast-enhanced brain magnetic resonance imaging and computed tomography. The tumor and adjacent relevant structures were identified and delimited. A sequential virtual simulation of the surgical stages for the approach was performed with the identification of local gyral and vascular patterns of the cerebral surface for posterior intraoperative recognition. Through virtual simulation, an optimal approach was gained. Accurate localization and complete removal of the lesion were achieved during the surgical procedure. Virtual presurgical planning with open-source software can be utilized for supratentorial pathologies in both urgent and elective cases. Virtual recognition of vascular and cerebral gyral patterns is helpful reference points for intraoperative localization of lesions lacking cortical expression, allowing less invasive corticotomies.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nDigital manipulation of cerebral structures can increase anatomical comprehension of neurosurgical lesions to be treated. 3D interpretation of neurosurgical pathologies and adjacent anatomical structures is essential for developing an effective and safe surgical approach. The described technique is a feasible and accessible option for presurgical planning.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_1075_2022","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T08:41:31Z","timestamp":1674808891000},"page":"32","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Virtual preoperative planning and 3D tumoral reconstruction with Horos open-source software"],"prefix":"10.25259","volume":"14","author":[{"given":"Derek O.","family":"Pipolo","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, Trauma and Emergency Hospital \u201cDr. Federico Abete\u201d, Buenos Aires, Argentina"},{"name":"LINT, Facultad de Medicina, Universidad Nacional de Tucum\u00e1n, Tucum\u00e1n, Argentina,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabino","family":"Luzzi","sequence":"additional","affiliation":[{"name":"Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Italy,"},{"name":"Neurosurgery Unit, Department of Surgical Sciences, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matias","family":"Baldoncini","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Hospital San Fernando, Argentina, USA"},{"name":"Laboratory of Microsurgical Neuroanatomy, Second Chair of Gross Anatomy, School of Medicine, University of Buenos Aires, Argentina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andres","family":"Di Pietrantonio","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Trauma and Emergency Hospital \u201cDr. Federico Abete\u201d, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Trauma and Emergency Hospital \u201cDr. Federico Abete\u201d, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humberto","family":"Asmus","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Trauma and Emergency Hospital \u201cDr. Federico Abete\u201d, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago J.","family":"Miyara","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice Giotta","family":"Lucifero","sequence":"additional","affiliation":[{"name":"Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Italy,"},{"name":"Department of Brain and Behavioral Sciences, University of Pavia, Italy,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro","family":"Campero","sequence":"additional","affiliation":[{"name":"LINT, Facultad de Medicina, Universidad Nacional de Tucum\u00e1n, Tucum\u00e1n, Argentina,"},{"name":"Department of Neurological Surgery, Hospital Padilla, Tucum\u00e1n, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2023,1,27]]},"reference":[{"key":"10.25259\/SNI_1075_2022\/ref-1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1055\/s-2006-948300","article-title":"Using the magnetic resonance three-dimensional volume rendering for tissues technique in the planning of craniotomy flaps with linear scalp incision","volume":"49","author":"Aydin","year":"2006","journal-title":"Minim Invasive Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-2","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1109\/TVCG.2007.70560","article-title":"High-quality multimodal volume rendering for preoperative planning of neurosurgical interventions","volume":"13","author":"Beyer","year":"2007","journal-title":"IEEE Trans Vis Comput Graph"},{"key":"10.25259\/SNI_1075_2022\/ref-3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.wneu.2022.09.086","article-title":"Single-stage complete removal of dumbbell-shaped trigeminal schwannoma: 3-Dimensional operative video","volume":"168","author":"Campero","year":"2022","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-4","first-page":"S2239253X20032843","article-title":"A 3D printed custom-made mask model for frameless neuronavigation during retrosigmoid craniotomy. A preclinical cadaveric feasibility study","volume":"9","author":"Canzi","year":"2020","journal-title":"Ann Ital Chir"},{"key":"10.25259\/SNI_1075_2022\/ref-5","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00701-009-0553-5","article-title":"Image-guided surgical planning using anatomical landmarks in the retrosigmoid approach","volume":"152","author":"da Silva","year":"2010","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_1075_2022\/ref-6","doi-asserted-by":"crossref","first-page":"e864","DOI":"10.1016\/j.wneu.2017.11.123","article-title":"Clinical application of an open-source 3D volume rendering software to neurosurgical approaches","volume":"110","author":"de Oliveira Santos","year":"2018","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1227\/NEU.0b013e3182748ee8","article-title":"Advanced 3-dimensional planning in neurosurgery","volume":"72","author":"Ferroli","year":"2013","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1075_2022\/ref-8","first-page":"5","article-title":"Innovative therapies for malignant brain tumors: The road to a tailored cure","volume":"91","author":"Giotta Lucifero","year":"2020","journal-title":"Acta Biomed"},{"key":"10.25259\/SNI_1075_2022\/ref-9","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1159\/000163555","article-title":"Virtually peeling off the skull and scalp: A simple way of mapping the superficial cerebral veins on the brain surface","volume":"86","author":"Gong","year":"2008","journal-title":"Stereotact Funct Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-10","first-page":"426","article-title":"Three-dimensional reconstruction of the topographical cerebral surface anatomy for presurgical planning with free OsiriX Software","volume":"10","author":"Harput","year":"2014","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1075_2022\/ref-11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3171\/jns.1990.72.3.0433","article-title":"Three-dimensional magnetic resonance images of the brain: Application to neurosurgical planning","volume":"72","author":"Hu","year":"1990","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-12","doi-asserted-by":"crossref","first-page":"S267","DOI":"10.4103\/2152-7806.137970","article-title":"Neurosurgical planning using osirix software","volume":"5","author":"Jaimovich","year":"2014","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_1075_2022\/ref-13","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.wneu.2019.07.065","article-title":"Three-dimensional volume rendering: An underutilized tool in neurosurgery","volume":"130","author":"Jha","year":"2019","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-14","doi-asserted-by":"crossref","first-page":"762","DOI":"10.4103\/ajns.AJNS_63_19","article-title":"The use of osirix for surgical planning using cranial measures and region of interest tools: Technical note","volume":"14","author":"Lovato","year":"2019","journal-title":"Asian J Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-15","doi-asserted-by":"crossref","first-page":"V10","DOI":"10.3171\/2021.10.FOCVID2157","article-title":"Microscope-based augmented reality with diffusion tensor imaging and fluorescein in insular glioma resection","volume":"6","author":"Luzzi","year":"2022","journal-title":"Neurosurg Focus Video"},{"key":"10.25259\/SNI_1075_2022\/ref-16","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.wneu.2021.12.072","article-title":"Postcentral gyrus high-grade glioma: Maximal safe anatomic resection guided by augmented reality with fiber tractography and fluorescein","volume":"159","author":"Luzzi","year":"2022","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-17","doi-asserted-by":"crossref","first-page":"E5","DOI":"10.3171\/2021.5.FOCUS21185","article-title":"Supratentorial high-grade gliomas: Maximal safe anatomical resection guided by augmented reality high-definition fiber tractography and fluorescein","volume":"51","author":"Luzzi","year":"2021","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI_1075_2022\/ref-18","first-page":"875","article-title":"Morphometric and radiomorphometric study of the correlation between the foramen magnum region and the anterior and posterolateral approaches to ventral intradural lesions","volume":"29","author":"Luzzi","year":"2019","journal-title":"Turk Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-19","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.3390\/s130506477","article-title":"3D preoperative planning in the ER with OsiriX\u00ae: When there is no time for neuronavigation","volume":"13","author":"Mandel","year":"2013","journal-title":"Sensors (Basel)"},{"key":"10.25259\/SNI_1075_2022\/ref-20","first-page":"ons286","article-title":"Brain tumor surgery with 3-dimensional surface navigation","volume":"71","author":"Mert","year":"2012","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1075_2022\/ref-21","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3171\/JNS\/2008\/108\/3\/0477","article-title":"Preoperative visualization of neurovascular anatomy in trigeminal neuralgia","volume":"108","author":"Miller","year":"2008","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-22","first-page":"339","article-title":"The role of osirix based virtual endoscopy in planning endoscopic transsphenoidal surgery for pituitary adenoma","volume":"27","author":"Rotariu","year":"2017","journal-title":"Turk Neurosurg"},{"key":"10.25259\/SNI_1075_2022\/ref-23","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/384460a0","article-title":"Role of learning in three-dimensional form perception","volume":"384","author":"Sinha","year":"1996","journal-title":"Nature"},{"key":"10.25259\/SNI_1075_2022\/ref-24","doi-asserted-by":"crossref","first-page":"241","DOI":"10.4103\/sni.sni_419_16","article-title":"OsiriX software as a preoperative planning tool in cranial neurosurgery: A step-by-step guide for neurosurgical residents","volume":"8","author":"Spiriev","year":"2017","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_1075_2022\/ref-25","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00701-009-0508-x","article-title":"Aneurysmal subarachnoid hemorrhage diagnosis with computed tomographic angiography and OsiriX","volume":"152","author":"Wang","year":"2010","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_1075_2022\/ref-26","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s10143-012-0395-0","article-title":"Localization of transverse-sigmoid sinus junction using preoperative 3D computed tomography: Application in retrosigmoid craniotomy","volume":"35","author":"Xia","year":"2012","journal-title":"Neurosurg Rev"},{"key":"10.25259\/SNI_1075_2022\/ref-27","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3109\/02688697.2010.496876","article-title":"Use of 3D visualisation of medical images for planning and intraoperative localisation of superficial brain tumours: Our experience","volume":"24","author":"Zele","year":"2010","journal-title":"Br J Neurosurg"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/virtual-preoperative-planning-and-3d-tumoral-reconstruction-with-horos-open-source-software\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/virtual-preoperative-planning-and-3d-tumoral-reconstruction-with-horos-open-source-software\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T08:41:53Z","timestamp":1674808913000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/virtual-preoperative-planning-and-3d-tumoral-reconstruction-with-horos-open-source-software\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,27]]},"references-count":27,"alternative-id":["10.25259\/SNI_1075_2022"],"URL":"https:\/\/doi.org\/10.25259\/sni_1075_2022","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,27]]},"article-number":"32"}}