{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T01:15:02Z","timestamp":1780794902075,"version":"3.54.1"},"reference-count":15,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background:<\/jats:title>\n<jats:p>Subependymal giant cell astrocytomas (SEGAs) appear approximately in 10% of patients with tuberous sclerosis. These tumors are most commonly diagnosed in childhood and adolescence, with <jats:italic>in utero<\/jats:italic> diagnosed SEGAs being an extremely rare entity.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description:<\/jats:title>\n<jats:p>We present the case of a congenital SEGA detected in an antenatal ultrasound and further investigated with fetal magnetic resonance imaging (MRI) scans at 22 and 32 weeks of gestational age. At 9 days of age, the child underwent craniotomy and partial excision of the tumor, followed by a second more extensive operation 13 days later. The patient was subsequently administered mammalian target of rapamycin inhibitor (everolimus).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>In the latest follow-up MRI, at the age of two, the SEGA remained unchanged. Management of these tumors in neonates is challenging, mainly due to high morbidity and mortality of surgical treatment in these ages.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_10_2019","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:00:41Z","timestamp":1582588841000},"page":"26","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Fetal subependymal giant cell astrocytoma: A case report and review of the literature"],"prefix":"10.25259","volume":"11","author":[{"given":"Aikaterini","family":"Karagianni","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, \u201cK.A.T.-N.R.C.\u201d General Hospital of Attica,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ploutarchos","family":"Karydakis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, 251 Hellenic Air Force General Hospital,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Giakoumettis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Athens, \u201cEvangelismos Hospital\u201d,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Nikas","sequence":"additional","affiliation":[{"name":"Departments of Imaging, Children\u2019s Hospital \u201cAghia Sofia\u201d, Athens, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Sfakianos","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Children\u2019s Hospital \u201cAghia Sofia\u201d, Athens, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Themistocleous","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Children\u2019s Hospital \u201cAghia Sofia\u201d, Athens, 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