{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T18:34:00Z","timestamp":1793471640970,"version":"4.5.0"},"reference-count":22,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>A retained medullary cord (RMC) is a relatively newly defined entity of closed spinal dysraphism that is thought to originate from regression failure of the medullary cord during secondary neurulation. A congenital dermal sinus (CDS) may provide a pathway for intraspinal infections such as repeated meningitis. Intramedullary abscesses are the rarest but most serious complication of a CDS.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>We treated a female infant with an intramedullary abscess in the thoracolumbar region, which was caused by infection of the CDS. Surgery revealed that the cord-like structure (C-LS) started from the cord with the intramedullary abscess, extended to the dural cul-de-sac, and further continued to the CDS tract and skin dimple. The boundary between the functional cord and the non-functional CL-S was electrophysiologically identified, and the entire length of the C-LS (the RMC) with an infected dermoid cyst was resected. As a result, the abscess cavity was opened and thorough irrigation and drainage of the pus could be performed. Histopathological examination of the C-LS revealed an infected dermoid cyst and abscess cavity with keratin debris in the fibrocollagenous tissue. The abscess cavity had a central canal-like ependymal lined lumen (CCLELL), with surrounding glial fibrillary acidic protein (GFAP)-immunopositive neuroglial tissues.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>We demonstrated that the transmission of an infection through the RMC was involved in the development of the intramedullary abscess. A good postoperative outcome was obtained because a terminal ventriculostomy for pus drainage could be achieved by excising the nonfunctional RMC.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_1197_2021","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T06:21:56Z","timestamp":1645165316000},"page":"54","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intramedullary abscess at thoracolumbar region transmitted from infected dermal sinus and dermoid through retained medullary cord"],"prefix":"10.25259","volume":"13","author":[{"given":"Yoshie","family":"Matsubara","sequence":"first","affiliation":[{"name":"Department of Pediatric Neurology, Fukuoka Children\u2019s Hospital, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuya","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fukuoka Children\u2019s Hospital, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Kurogi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fukuoka Children\u2019s Hospital, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sooyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, National Hospital Organization, Fukuoka-Higashi Medical Center, Koga, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Mukae","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takafumi","family":"Shimogawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadahisa","family":"Shono","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Harasanshin Hospital, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi O.","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Shourai Hospital, Karatsu, Saga, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Yoshimoto","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takato","family":"Morioka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Harasanshin Hospital, Fukuoka,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,2,18]]},"reference":[{"key":"10.25259\/SNI_1197_2021\/ref-1","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1007\/s00586-009-0885-0","article-title":"Management of intramedullary spinal cord abscess: Experience with four cases, pathophysiology and outcomes","volume":"18","author":"Al Barbarawi","year":"2009","journal-title":"Eur Spine J"},{"key":"10.25259\/SNI_1197_2021\/ref-2","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1007\/s00381-016-3108-0","article-title":"Intramedullary dermoid cyst infection mimicking holocord tumor: Should radical resection be mandatory? 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