{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T15:06:10Z","timestamp":1774019170032,"version":"3.50.1"},"reference-count":19,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Fibrous hamartoma of Infancy (FHI) is a rare, benign mesenchymal lesion typically presenting within the first 2 years of life. While it commonly occurs in the axilla, shoulder, or upper trunk, lumbosacral involvement is exceptionally rare and can mimic other congenital or neoplastic lesions, leading to diagnostic difficulty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Case Description:<\/jats:title>\n                    <jats:p>We report a 10-month-old male infant with a 7-month history of a progressively enlarging midline lumbosacral mass. The swelling, measuring 15 \u00d7 13 cm, was soft, non-tender, and had ill-defined margins. Initial ultrasonography was inconclusive. Magnetic resonance imaging (MRI) of the spine showed a heterogeneous subcutaneous lesion without spinal cord involvement. Complete excision biopsy was performed, and histopathology confirmed the diagnosis of FHI, showing the characteristic triphasic pattern of mature adipose tissue, fibrocollagenous stroma, and immature mesenchymal elements. The postoperative course was uneventful, and the patient remains well at 2 months of follow-up with no evidence of recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Lumbosacral FHI is exceedingly rare and diagnostically challenging, usually requiring MRI for lesion delineation and histopathology for definitive diagnosis. Prognosis is excellent following complete surgical excision. A high index of suspicion is essential to avoid misdiagnosis and unnecessary intervention. In low-resource settings, structural and economic barriers may significantly delay access to appropriate care. Strengthening healthcare infrastructure and improving diagnostic pathways are essential to ensure timely management and good clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/sni_1212_2025","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T13:33:10Z","timestamp":1774013590000},"page":"159","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fibrous hamartoma of infancy in the lumbosacral region: A case report of a rare soft-tissue tumor"],"prefix":"10.25259","volume":"17","author":[{"given":"Ruth","family":"Agyekum","sequence":"first","affiliation":[{"name":"Department of Public Health, Johns Hopkins University, Baltimore, Maryland, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberta","family":"Anati","sequence":"additional","affiliation":[{"name":"Department of Surgery, Greater Accra Regional Hospital, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicia Naa Adjorkor","family":"Kpoh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Greater Accra Regional Hospital, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stella Akoma","family":"Twerefou","sequence":"additional","affiliation":[{"name":"Department of Surgery, Greater Accra Regional Hospital, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassanatu Yeanie","family":"Kanu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Princess Christian Maternity Hospital, Freetown, Sierra Leone"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane Nyajay","family":"Tucker","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Princess Christian Maternity Hospital, Freetown, Sierra Leone"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Amenuveve","sequence":"additional","affiliation":[{"name":"Department of Surgery, Greater Accra Regional Hospital, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuna","family":"Josiah","sequence":"additional","affiliation":[{"name":"Department of Surgery, Greater Accra Regional Hospital, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al-hassan Dasana","family":"Andani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Greater Accra Regional Hospital, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,3,20]]},"reference":[{"key":"10.25259\/SNI_1212_2025\/ref-1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/modpathol.2016.215","article-title":"Fibrous hamartoma of infancy: A clinicopathologic study of 145 cases, including 2 with sarcomatous features","volume":"30","author":"Al-Ibraheemi","year":"2017","journal-title":"Mod Pathol"},{"key":"10.25259\/SNI_1212_2025\/ref-2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s100249900119","article-title":"Fibrous hamartoma of infancy: Current review","volume":"2","author":"Dickey","year":"1999","journal-title":"Pediatr Dev Pathol"},{"key":"10.25259\/SNI_1212_2025\/ref-3","doi-asserted-by":"crossref","first-page":"e555","DOI":"10.1542\/neo.16-9-e555","article-title":"Case 2: A midline lumbosacral mass","volume":"16","author":"Eldridge","year":"2015","journal-title":"Neoreviews"},{"key":"10.25259\/SNI_1212_2025\/ref-4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00383-004-1357-6","article-title":"A case of recurrent and synchronous fibrous hamartoma of infancy","volume":"21","author":"Imaji","year":"2005","journal-title":"Pediatr Surg Int"},{"key":"10.25259\/SNI_1212_2025\/ref-5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4174\/jkss.2011.81.1.61","article-title":"Fibrous hamartoma of infancy: An experience of a single institute","volume":"81","author":"Kang","year":"2011","journal-title":"J Korean Surg Soc"},{"key":"10.25259\/SNI_1212_2025\/ref-6","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0022-3468(88)80420-2","article-title":"Fibrous hamartoma of infancy","volume":"23","author":"Lee","year":"1988","journal-title":"J Pediat Surg"},{"key":"10.25259\/SNI_1212_2025\/ref-7","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s00256-014-1838-1","article-title":"Ultrasonographic features of fibrous hamartoma of infancy","volume":"43","author":"Lee","year":"2014","journal-title":"Skeletal Radiol"},{"key":"10.25259\/SNI_1212_2025\/ref-8","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1007\/s00330-015-3878-x","article-title":"Differentiation of malignant from benign soft tissue tumours: Use of additive qualitative and quantitative diffusion-weighted MR imaging to standard MR imaging at 3.0 T","volume":"26","author":"Lee","year":"2016","journal-title":"Eur Radiol"},{"key":"10.25259\/SNI_1212_2025\/ref-9","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/pde.12459","article-title":"Fibrous hamartoma of infancy: A firm plaque presenting with hypertrichosis and hyperhidrosis","volume":"32","author":"Melnick","year":"2015","journal-title":"Pediatr Dermatol"},{"key":"10.25259\/SNI_1212_2025\/ref-10","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1007\/s00247-023-05701-x","article-title":"Fibrous hamartoma of infancy: Imaging findings","volume":"53","author":"Morales","year":"2023","journal-title":"Pediatr Radiol"},{"key":"10.25259\/SNI_1212_2025\/ref-11","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/1754-9485.12499","article-title":"Congenital anomalies of lumbosacral spine: A pictorial review","volume":"61","author":"Naffaa","year":"2017","journal-title":"J Med Imaging Radiat Oncol"},{"key":"10.25259\/SNI_1212_2025\/ref-12","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00381-023-06133-6","article-title":"Fibrous hamartoma of infancy of the spinal cord resembling conus and filum, with a coexisting sacral dimple","volume":"40","author":"Park","year":"2024","journal-title":"Childs Nerv Syst"},{"key":"10.25259\/SNI_1212_2025\/ref-13","doi-asserted-by":"crossref","first-page":"152075","DOI":"10.1016\/j.anndiagpath.2022.152075","article-title":"Fibrous hamartoma of infancy. Radiologic-pathologic study of 21 cases: 8 with predominant pseudoangiomatous pattern","volume":"62","author":"Pena-Burgos","year":"2023","journal-title":"Ann Diagn Pathol"},{"key":"10.25259\/SNI_1212_2025\/ref-14","doi-asserted-by":"crossref","first-page":"11190","DOI":"10.12998\/wjcc.v10.i30.11190","article-title":"Fibrous hamartoma of infancy with bone destruction of the tibia: A case report","volume":"10","author":"Qiao","year":"2022","journal-title":"World J Clin Cases"},{"key":"10.25259\/SNI_1212_2025\/ref-15","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/PAS.0000000000000104","article-title":"Fibrous hamartoma of infancy: A clinicopathologic analysis of 60 cases","volume":"38","author":"Saab","year":"2014","journal-title":"Am J Surg Pathol"},{"key":"10.25259\/SNI_1212_2025\/ref-16","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.jpedsurg.2010.12.026","article-title":"Fibrous hamartoma of infancy","volume":"46","author":"Seguier-Lipszyc","year":"2011","journal-title":"J Pediatr Surg"},{"key":"10.25259\/SNI_1212_2025\/ref-17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.4103\/2229-5178.79867","article-title":"Fibrous hamartoma of infancy","volume":"2","author":"Vinayak","year":"2011","journal-title":"Indian Dermatol Online J"},{"key":"10.25259\/SNI_1212_2025\/ref-18","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1227\/01.NEU.0000134614.73236.A4","article-title":"Spinal fibrous hamartoma of infancy: Case report","volume":"55","author":"Yano","year":"2004","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1212_2025\/ref-19","first-page":"3374","article-title":"Fibrous hamartoma of infancy: A clinical pathological analysis of seventeen cases","volume":"8","author":"Yu","year":"2015","journal-title":"Int J Clin Exp Pathol"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/fibrous-hamartoma-of-infancy-in-the-lumbosacral-region-a-case-report-of-a-rare-soft-tissue-tumor\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/fibrous-hamartoma-of-infancy-in-the-lumbosacral-region-a-case-report-of-a-rare-soft-tissue-tumor\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T13:33:12Z","timestamp":1774013592000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/fibrous-hamartoma-of-infancy-in-the-lumbosacral-region-a-case-report-of-a-rare-soft-tissue-tumor\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,20]]},"references-count":19,"alternative-id":["10.25259\/SNI_1212_2025"],"URL":"https:\/\/doi.org\/10.25259\/sni_1212_2025","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,20]]},"article-number":"159"}}