{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T08:07:32Z","timestamp":1776413252868,"version":"3.51.2"},"reference-count":21,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Carotid web (CW) is an intraluminal, ridge-like projection arising from the posterior wall of the carotid bifurcation. It is recognized as a risk factor for ischemic stroke and has been increasingly identified as a potential cause of recurrent embolic strokes of undetermined source (ESUS). However, the relationship between CW and stroke size, as well as how CW compares with internal carotid artery stenosis (ICAS), remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted of 98 patients who underwent carotid endarterectomy (CEA) for symptomatic ICAS or CW. Demographics, stroke size, and the presence of thrombus associated with CW were evaluated. Diffusion-weighted magnetic resonance imaging and carotid angiography were used to assess stroke size and identify CW.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The prevalence of CW in the cohort was 5.1%. Patients with CW experienced significantly larger strokes compared with those with ICAS (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.006). In addition, 40% of CW lesions were accompanied by thrombus formation, suggesting an increased likelihood of larger infarctions and recurrent events.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Compared to ICAS, CW was associated with larger embolic strokes, and its frequent association with thrombus formation further elevates the risk of recurrence. In patients presenting with larger infarctions, careful evaluation of the carotid artery is warranted to identify potential CW.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/sni_1260_2025","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:26:30Z","timestamp":1776410790000},"page":"221","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Carotid web as a risk factor for large stroke: Prevalence in consecutive carotid endarterectomy cases"],"prefix":"10.25259","volume":"17","author":[{"given":"Shigeomi","family":"Yokoya","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Saiseikai Shiga Hospital, Imperial Gift Foundation Inc., Ritto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidesato","family":"Takezawa","sequence":"additional","affiliation":[{"name":"Department of Neurology, Saiseikai Shiga Hospital, Imperial Gift Foundation Inc., Ritto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Oka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saiseikai Shiga Hospital, Imperial Gift Foundation Inc., Ritto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"10.25259\/SNI_1260_2025\/ref-1","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1136\/jnis-2023-021243","article-title":"Carotid webs: A review of pathophysiology, diagnostic findings, and treatment options","volume":"16","author":"Chen","year":"2024","journal-title":"J Neurointerv Surg"},{"key":"10.25259\/SNI_1260_2025\/ref-2","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.3174\/ajnr.A4431","article-title":"Carotid webs and recurrent ischemic strokes in the era of CT angiography","volume":"36","author":"Choi","year":"2015","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.25259\/SNI_1260_2025\/ref-3","first-page":"703","article-title":"Flow patterns in carotid webs: A patient-based computational fluid dynamics study","volume":"40","author":"Compagne","year":"2019","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.25259\/SNI_1260_2025\/ref-4","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1148\/radiol.2017170094","article-title":"Prevalence of carotid web in patients with acute intracranial stroke due to intracranial large vessel occlusion","volume":"286","author":"Compagne","year":"2018","journal-title":"Radiology"},{"key":"10.25259\/SNI_1260_2025\/ref-5","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1212\/WNL.0000000000003464","article-title":"Carotid artery web and ischemic stroke: A case-control study","volume":"88","author":"Coutinho","year":"2017","journal-title":"Neurology"},{"key":"10.25259\/SNI_1260_2025\/ref-6","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1177\/1591019916633245","article-title":"Neurointerventional management of carotid webs associated with recurrent and acute cerebral ischemic syndromes","volume":"22","author":"Elmokadem","year":"2016","journal-title":"Interv Neuroradiol"},{"key":"10.25259\/SNI_1260_2025\/ref-7","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1186\/s12883-021-02428-w","article-title":"Histologic differences between in situ and embolized carotid web thrombi: A case report","volume":"21","author":"Gao","year":"2021","journal-title":"BMC Neurol"},{"key":"10.25259\/SNI_1260_2025\/ref-8","doi-asserted-by":"crossref","first-page":"63","DOI":"10.31486\/toj.18.0143","article-title":"Carotid web stenting","volume":"19","author":"Gouveia","year":"2019","journal-title":"Ochsner J"},{"key":"10.25259\/SNI_1260_2025\/ref-9","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1017\/cjn.2021.182","article-title":"Caught red-handed: Angiography reveals large thrombus in carotid web of stroke patient","volume":"49","author":"Hadwen","year":"2022","journal-title":"Can J Neurol Sci"},{"key":"10.25259\/SNI_1260_2025\/ref-10","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1159\/000489710","article-title":"Multicenter experience with stenting for symptomatic carotid web","volume":"7","author":"Haussen","year":"2018","journal-title":"Interv Neurol"},{"key":"10.25259\/SNI_1260_2025\/ref-11","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.neurad.2015.10.004","article-title":"MRI characteristics of carotid bulb atypical fibromuscular dysplasia in black stroke patients","volume":"43","author":"Joux","year":"2016","journal-title":"J Neuroradiol"},{"key":"10.25259\/SNI_1260_2025\/ref-12","first-page":"659","article-title":"Reconsideration of carotid web and the therapeutic strategy","volume":"47","author":"Kawahara","year":"2019","journal-title":"No Shinkei Geka"},{"key":"10.25259\/SNI_1260_2025\/ref-13","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1161\/01.STR.8.5.617","article-title":"Angiographic spectrum of cervical and intracranial fibromuscular dysplasia","volume":"8","author":"Osborn","year":"1977","journal-title":"Stroke"},{"key":"10.25259\/SNI_1260_2025\/ref-14","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1007\/s00701-020-04272-2","article-title":"Carotid web leads to new thrombus formation: Computational fluid dynamic analysis coupled with histological evidence","volume":"162","author":"Ozaki","year":"2020","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_1260_2025\/ref-15","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.3174\/ajnr.A5208","article-title":"Carotid bulb webs as a cause of \u201ccryptogenic\u201d ischemic stroke","volume":"38","author":"Sajedi","year":"2017","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"10.25259\/SNI_1260_2025\/ref-16","doi-asserted-by":"crossref","first-page":"42","DOI":"10.2335\/scs.52.42","article-title":"Histopathological evaluation of in situ and distal Embolic thrombi of a symptomatic carotid web: A case report (In Japanese)","volume":"52","author":"Senbokuya","year":"2024","journal-title":"Surg Cereb Stroke (Jpn)"},{"key":"10.25259\/SNI_1260_2025\/ref-17","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/s13760-020-01353-y","article-title":"Imaging and clinical features of cervical artery web: Report of 41 cases and literature review","volume":"121","author":"Wang","year":"2021","journal-title":"Acta Neurol Belg"},{"key":"10.25259\/SNI_1260_2025\/ref-18","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.3171\/2020.8.JNS201727","article-title":"Prevalence and site of predilection of carotid webs focusing on symptomatic and asymptomatic Japanese patients","volume":"135","author":"Yang","year":"2021","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_1260_2025\/ref-19","doi-asserted-by":"crossref","first-page":"3000605211059929","DOI":"10.1177\/03000605211059929","article-title":"Embolectomy of acute embolic stroke associated with ipsilateral carotid web: A case report and literature review","volume":"49","author":"Yin","year":"2021","journal-title":"J Int Med Res"},{"key":"10.25259\/SNI_1260_2025\/ref-20","doi-asserted-by":"crossref","first-page":"2872","DOI":"10.1161\/STROKEAHA.118.021907","article-title":"A systematic literature review of patients with carotid web and acute ischemic stroke","volume":"49","author":"Zhang","year":"2018","journal-title":"Stroke"},{"key":"10.25259\/SNI_1260_2025\/ref-21","first-page":"599","article-title":"A clinical analysis of 32 patients with carotid web","volume":"58","author":"Zhou","year":"2019","journal-title":"Zhonghua Nei Ke Za Zhi"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/carotid-web-as-a-risk-factor-for-large-stroke-prevalence-in-consecutive-carotid-endarterectomy-cases\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/carotid-web-as-a-risk-factor-for-large-stroke-prevalence-in-consecutive-carotid-endarterectomy-cases\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:26:37Z","timestamp":1776410797000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/carotid-web-as-a-risk-factor-for-large-stroke-prevalence-in-consecutive-carotid-endarterectomy-cases\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,17]]},"references-count":21,"alternative-id":["10.25259\/SNI_1260_2025"],"URL":"https:\/\/doi.org\/10.25259\/sni_1260_2025","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,17]]},"article-number":"221"}}