{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T10:05:39Z","timestamp":1780653939499,"version":"3.54.1"},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Von Willebrand disease (VWD) is the most common inherited bleeding disorder. Spinal intradural extramedullary hematoma (SIEH) is an exceptionally rare manifestation.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n A 28-year-old woman with VWD developed spontaneous SIEH following mild exercise, presenting with back pain, progressive lower limb weakness, and double incontinence. Magnetic resonance imaging (MRI) demonstrated a T3\/4 intradural extramedullary hematoma. Urgent surgical evacuation through T3\/4 fenestration was performed, followed by targeted hemostatic therapy with recombinant von Willebrand factor (Vonicog Alfa). The patient made a complete neurological recovery within 3 months and remained asymptomatic at 14-month follow-up.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n SIEH should be considered in VWD patients presenting with acute spinal symptoms, even without trauma. Early MRI, prompt decompression, and tailored coagulation management are critical to optimal outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_1357_2025","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T09:21:38Z","timestamp":1780651298000},"page":"335","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous intradural extramedullary hematoma after mild exercise in Von Willebrand disease: A rare clinical presentation and literature review"],"prefix":"10.25259","volume":"17","author":[{"given":"Ali","family":"Bukhari","sequence":"first","affiliation":[{"name":"Department of Trauma and Orthopaedics, Stepping Hill Hospital, Stockport, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apostolos","family":"Lagaras","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedics,, Salford Royal Hospital, Greater Manchester, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Dherijha","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Salford Royal Hospital, Greater Manchester, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedics, Royal Oldham Hospital, Oldham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Shahid","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedics, Royal Blackburn Teaching Hospital, Lancashire, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"10.25259\/SNI_1357_2025\/ref-1","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jemermed.2013.04.048","article-title":"Acute 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