{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T10:40:28Z","timestamp":1742553628029,"version":"3.40.2"},"reference-count":9,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background<\/jats:title>\n<jats:p>Spinal subdural empyema rarely involves the spinal cord and may result in devastating neurological deficits. These lesions typically require prompt diagnosis, surgical evacuation, and antibiotic therapy. Here, we present the clinical course, imaging, and narrated operative video of a thoracic spinal subdural empyema initially diagnosed as an intramedullary neoplasm.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description<\/jats:title>\n<jats:p>A 73-year-old female presented with a 6-month history of worsening thoracic myelopathy; over the last few weeks, she rapidly developed paraplegia. She was initially diagnosed with an enlarging thoracic intramedullary mass. A spinal biopsy was performed for the presumptive diagnosis of primary intramedullary central nervous system lymphoma. However, at surgery, the thoracic lesion proved to be a chronic subdural empyema (i.e., surrounded by arachnoid granulations and soft-purulent tissue). Interestingly, the operative specimen failed to grow any specific organism.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Spinal subdural empyema should be one of the differential diagnoses considered for patients presenting with intradural spinal cord lesions.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_141_2025","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T10:25:07Z","timestamp":1742552707000},"page":"95","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spinal subdural empyema: A two-dimensional illustrative operative video"],"prefix":"10.25259","volume":"16","author":[{"given":"Seung Jin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, Mayo Clinic Florida, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loizos","family":"Michaelides","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Mayo Clinic Florida, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saarang","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, UC Irvine, Orange, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian Lassiter","family":"Gendreau","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Johns Hopkins, Baltimore, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nolan J.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, UC Irvine, Orange, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Clifton","sequence":"additional","affiliation":[{"name":"Center for Spine Health, Department of Neurosurgery, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Edgar","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Mayo Clinic, Jacksonville, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukhwinder","family":"Sandhu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Jacksonville, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selby","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Mayo Clinic Florida, Jacksonville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2025,3,21]]},"reference":[{"key":"10.25259\/SNI_141_2025\/ref-1","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1227\/01.NEU.0000053223.77641.5E","article-title":"Spinal cord biopsy: A review of 38 cases","volume":"52","author":"Cohen-Gadol","year":"2003","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_141_2025\/ref-2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.rcl.2010.07.018","article-title":"Spine infection\/inflammation","volume":"49","author":"DeSanto","year":"2011","journal-title":"Radiol Clin N Am"},{"key":"10.25259\/SNI_141_2025\/ref-3","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1212\/WNL.0b013e31822b00b9","article-title":"Primary intramedullary spinal cord 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