{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T09:14:28Z","timestamp":1775207668847,"version":"3.50.1"},"reference-count":14,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Achieving an optimal balance between the maximal possible extent of resection and preservation of neurological function remains a major challenge in neuro-oncology, particularly in tumors located within functionally eloquent areas. Intraoperative ultrasound (IOUS) provides real-time visualization, potentially enhancing surgical precision and improving clinical outcomes.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A retrospective comparative analysis was conducted on 90 patients, divided into two groups: IOUS (\n n<\/jats:italic>\n = 45; resection under ultrasound guidance) and control (\n n<\/jats:italic>\n = 45; standard resection without navigation). Evaluated outcomes included the extent of resection based on magnetic resonance imaging, postoperative motor deficit (assessed by the Medical Research Council scale), and occurrence of early (\u226430 days) and late (>30 days)\n de novo<\/jats:italic>\n seizures.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The extent of resection was comparable between groups (94.5% vs. 91.8%,\n P =<\/jats:italic>\n 0.09). New postoperative motor deficits were less frequent in the IOUS group (15.6% vs. 31.1%,\n P =<\/jats:italic>\n 0.07). The incidence of early\n de novo<\/jats:italic>\n seizures was significantly lower in the IOUS group (8.9% vs. 28.9%,\n P =<\/jats:italic>\n 0.02).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The use of IOUS in the resection of tumors of the right nondominant frontal lobe enables a high extent of resection, shows a trend toward better preservation of neurological function, and significantly reduces the risk of early postoperative seizures.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_1439_2025","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T08:17:30Z","timestamp":1775204250000},"page":"203","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of intraoperative ultrasound guidance on resection of nondominant frontal lobe tumors: Effects on extent of resection, neurological status, and postoperative seizures"],"prefix":"10.25259","volume":"17","author":[{"given":"Uygun U.","family":"Altibayev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sardorkhoja A.","family":"Sizdikkhodjaev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakhongirmirzo Z.","family":"Yoldoshev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robiya R.","family":"Uzakova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjar Bahromali o\u2019g\u2019li","family":"Tojimatov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"10.25259\/SNI_1439_2025\/ref-1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s11060-018-2862-0","article-title":"Tumor-related 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systematic review and meta-analysis","volume":"9","author":"Shah","year":"2023","journal-title":"Tomography"},{"key":"10.25259\/SNI_1439_2025\/ref-11","doi-asserted-by":"crossref","first-page":"E14","DOI":"10.3171\/2020.10.FOCUS20550","article-title":"Navigated ultrasound-based image guidance during resection of gliomas: Practical utility in intraoperative decision-making and outcomes","volume":"50","author":"Shetty","year":"2021","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI_1439_2025\/ref-12","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/ana.24522","article-title":"Predictors of preoperative and early postoperative seizures in patients with intra-axial primary and metastatic brain tumors: A retrospective observational single center study","volume":"78","author":"Skardelly","year":"2015","journal-title":"Ann 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