{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:26:08Z","timestamp":1780514768583,"version":"3.54.1"},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Neurological manifestations of paracoccidioidomycosis are uncommon, and the clinical presentation can include a variety of symptoms that depends specially on the lesion\u2019s site.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n This article reports the case of a 63-year-old rural worker who presented with progressive imbalance and diplopia. Magnetic resonance imaging suggested a likely inflammatory\/infectious etiology. The diagnosis was confirmed by the intraoperative frozen section and direct microscopic examination. Treatment started with amphotericin B and, later on, with itraconazole due to decreased renal function. The patient responded well and had improvement in symptoms.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Being aware of the patient environment is crucial for diagnosing neuroparacoccidioidomycosis. A detailed anamnesis, with description of professional and residence location, as well as other risky activities, should be done. The treatment must be individualized depending on clinical conditions and comorbidities, but amphotericin B and itraconazole are the most indicated and standardized options.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_1454_2025","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:26:14Z","timestamp":1776410774000},"page":"218","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Infratentorial neuroparacoccidioidomycosis: A case report"],"prefix":"10.25259","volume":"17","author":[{"given":"Diogo Scheffer","family":"Della Bona","sequence":"first","affiliation":[{"name":"Medical School, University of Passo Fundo, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romildo Antonio","family":"dos Santos J\u00fanior","sequence":"additional","affiliation":[{"name":"Medical School, Atitus, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Moacir","family":"Mesquita Filho","sequence":"additional","affiliation":[{"name":"Neurosurgery Service, Clinical Hospital, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice Estivalete","family":"Penno","sequence":"additional","affiliation":[{"name":"Medical School, University of Passo Fundo, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo Baldo","family":"Mesa Casa","sequence":"additional","affiliation":[{"name":"Medical School, Universidade Federal da Fronteira Sul, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula Giolo","family":"Franz","sequence":"additional","affiliation":[{"name":"Bioexperimentation Postgraduate Program, University of Passo Fundo, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Schwingel","sequence":"additional","affiliation":[{"name":"Pathology Institute, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wagner Lazaretto","family":"Padua","sequence":"additional","affiliation":[{"name":"Neurosurgery Service, Clinical Hospital, Passo Fundo, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"10.25259\/SNI_1454_2025\/ref-1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/107327480801500102","article-title":"Practical issues of intraoperative frozen section diagnosis of bone and soft tissue lesions","volume":"15","author":"Bui","year":"2008","journal-title":"Cancer Control"},{"issue":"Pt 1","key":"10.25259\/SNI_1454_2025\/ref-2","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1097\/00005537-200010000-00039","article-title":"Accuracy, utility, and cost of frozen section margins in head and neck cancer surgery","volume":"110","author":"DiNardo","year":"2000","journal-title":"Laryngoscope"},{"key":"10.25259\/SNI_1454_2025\/ref-3","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1590\/S0037-86822009000600016","article-title":"Paracoccidioidomicose com comprometimento do sistema nervoso central: Revis\u00e3o sistem\u00e1tica da literatura [Paracoccidioidomycosis compromising the central nervous system: A systematic review of the literature]","volume":"42","author":"Pedroso","year":"2009","journal-title":"Rev Soc Bras Med Trop"},{"key":"10.25259\/SNI_1454_2025\/ref-4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF01102913","article-title":"Neuroparacoccidioidomycosis: Case reports and review","volume":"127","author":"Pl\u00e1","year":"1994","journal-title":"Mycopathologia"},{"key":"10.25259\/SNI_1454_2025\/ref-5","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s11046-012-9607-y","article-title":"Neuroparacoccidioidomycosis (NPCM): Magnetic resonance imaging (MRI) findings","volume":"175","author":"Reis","year":"2013","journal-title":"Mycopathologia"},{"key":"10.25259\/SNI_1454_2025\/ref-6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.25259\/SNI_224_2020","article-title":"Isolated neuroparacoccidioidomycosis as a pseudotumoral lesion in the absence of systemic disease","volume":"11","author":"Riechelmann","year":"2020","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_1454_2025\/ref-7","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1590\/0037-8682-0230-2017","article-title":"Brazilian guidelines for the clinical management of paracoccidioidomycosis","volume":"50","author":"Shikanai-Yasuda","year":"2017","journal-title":"Rev Soc Bras Med Trop"},{"key":"10.25259\/SNI_1454_2025\/ref-8","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1590\/S0036-46652000000400009","article-title":"Central nervous system paracoccidioidomycosis. 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