{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:42:36Z","timestamp":1762868556219},"reference-count":12,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p><jats:bold \/> In stable craniovertebral injuries complicated by polytrauma, rigorous spinal immobilization is essential for neuroprotection. Scalp and forehead reconstruction in these circumstances are safest when performed under local anesthesia, maintaining cervical immobilization.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A sizeable 10 \u00d7 6.5 cm forehead defect was reconstructed utilizing regenerative principles under local anesthesia and sedation in a 54-year-old woman. After adequate debridement of gangrenous soft tissues, exposed outer skull bones were trephined, forehead defect covered with a synthetic biomaterial, and the patient was discharged thereafter. Granulating neodermis regenerated within the biomaterial over the next 6 weeks. Weekly platelet-rich plasma injections along the wound margins facilitated wound regeneration. Dimensions reduced by two-thirds to 6.5 \u00d7 3.5 cm with wound regeneration and contraction, while granulating neodermis covered the remaining skull-bones. Split skin-grafting over the neodermis ensured satisfying long-term results, with similar color, texture, soft-tissue thickness, and sensation. Multiple occipitocervical, spinal, scapular, and rib fractures healed well with strict immobilization.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Good long-term results were achieved with significantly reduced dangers, complications, hospitalization, and costs than traditional reconstructive flap surgeries. Minimalistic reconstruction utilizing tissue engineering and regenerative medicine principles appears beneficial for patients with grave spinal injuries.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_14_2021","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T06:36:53Z","timestamp":1622443013000},"page":"248","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Minimalistic reconstruction of exposed skull in a complex craniovertebral polytrauma"],"prefix":"10.25259","volume":"12","author":[{"given":"Srinjoy","family":"Saha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"10.25259\/SNI_14_2021\/ref-1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.4103\/1673-5374.202916","article-title":"Anesthetic considerations for patients with acute cervical 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of the occipital condyle clinical spectrum and course in eight patients","volume":"4","author":"Kr\u00fcger","year":"2013","journal-title":"J Craniovertebr Junction Spine"},{"key":"10.25259\/SNI_14_2021\/ref-9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1055\/s-0032-1322534","article-title":"Free flap reconstruction for complex scalp and forehead defects with associated full-thickness calvarial bone resections","volume":"5","author":"Larra\u00f1aga","year":"2012","journal-title":"Craniomaxillofac Trauma Reconstr"},{"key":"10.25259\/SNI_14_2021\/ref-10","first-page":"24","article-title":"Triple-plane dissection of combined forehead and scalp flaps for large posttraumatic forehead defects","volume":"6","author":"Saha","year":"2020","journal-title":"Int J Recent Surg Med Sci"},{"key":"10.25259\/SNI_14_2021\/ref-11","first-page":"8634831","article-title":"Surgical treatment for occipital condyle fracture, C1 dislocation, and cerebellar contusion with hemorrhage after blunt head trauma","volume":"2016","author":"Ueda","year":"2016","journal-title":"Case Rep Orthop"},{"key":"10.25259\/SNI_14_2021\/ref-12","first-page":"252","article-title":"Platelet-rich plasma improves healing of pressure ulcers as objectively assessed by digital planimetry","volume":"31","author":"Volakakis","year":"2019","journal-title":"Wounds"}],"container-title":["Surgical Neurology 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