{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:34:38Z","timestamp":1783654478872,"version":"3.55.0"},"reference-count":24,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\"><jats:title>Background:<\/jats:title><jats:p>Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor. In our knowledge, only 30 cases of brain metastasis were reported in literature. The authors report a case of 57-year-old male with elevated intracranial pressure signs, which a frontal mass with pathological diagnosis of MCC.<\/jats:p><\/jats:sec><jats:sec id=\"st2\"><jats:title>Case Description:<\/jats:title><jats:p>A 57-year-old male was admitted with a 3-month history of progressive headache, associated with nausea and dizziness. The magnetic resonance imaging showed a left frontal lobe, parasagittal, and nodular lesion with perilesional edema. The patient underwent complete surgical resection with success. The adjuvant treatment was radiotherapy and chemotherapy.<\/jats:p><\/jats:sec><jats:sec id=\"st3\"><jats:title>Conclusion:<\/jats:title><jats:p>In our knowledge, there is a little number of cases of MCC reported in literature. Surgical management is considered in cases with intracranial hypertension or focal signs. The adjuvant treatment options are immunotherapy and radiotherapy.<\/jats:p><\/jats:sec>","DOI":"10.25259\/sni_166_2019","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T14:10:20Z","timestamp":1568124620000},"page":"172","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Brain metastasis of Merkel cell carcinoma \u2013 A rare case report"],"prefix":"10.25259","volume":"10","author":[{"given":"Ricardo Louren\u00e7o","family":"Caramanti","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Faculdade de Medicina de S\u00e3o Jos\u00e9 do Rio Preto, S\u00e3o Jos\u00e9 do Rio Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feres Eduardo","family":"Chaddad Neto","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, 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