{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:53:57Z","timestamp":1788929637858,"version":"build-2803163510"},"reference-count":14,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>We analyzed the clinical and radiological parameters influencing functional outcomes and neurological recovery in patients with cervicothoracic junctional tuberculosis (TB).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Methods: <\/jats:title>\n<jats:p>This was a retrospective analysis of 16 cases of cervicothoracic junction (CTJ) spinal TB; 11 patients were managed operatively, while five were managed conservatively. Patients\u2019 outcomes were assessed at 1 month, 1 year, and yearly thereafter and included an analysis of multiple outcome scores, various radiographic parameters, and sensitivity or resistance to anti-tubercular therapy.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results: <\/jats:title>\n<jats:p>Patients averaged 25.94 years of age, and typically had three-level vertebral involvement. They were followed for a mean duration of 24 months, and the duration of anti-tubercular therapy averaged 17 months. Patients demonstrated clinical improvement on Japanese Orthopedic Association score and Neck disability index (<jats:italic>P<\/jats:italic> &lt; 0.005) starting from 1 month following initiation of treatment which continued in subsequent follow-up, along with change in radiological parameters consisting of mean segmental kyphotic angle from 18.98\u00b0 to 15.13\u00b0, C2\u2013C7 SVA from 16.13 mm to 22.61 mm, T1 slope from 22.80\u00b0 to 14.66\u00b0, thoracic inlet angle from 75.35\u00b0 to 63.25\u00b0, neck tilt from 51.81\u00b0 to 48.33\u00b0, and cervical lordosis from 4.66\u00b0 to \u22120.44\u00b0 (<jats:italic>P<\/jats:italic> &gt; 0.05) at the end of 1 year.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Tuberculous affection of the dynamic CTJ is a challenging scenario in clinical practice and its management involves consideration of disease extent, neurological status, and effort toward restoration of normal alignment of spine in sagittal and coronal plane to get favorable clinical outcomes.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_167_2022","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T06:12:19Z","timestamp":1652681539000},"page":"198","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Functional outcomes in the management of cervicothoracic junction tuberculosis"],"prefix":"10.25259","volume":"13","author":[{"given":"Tushar Narayan","family":"Rathod","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivaprasad Sharangouda","family":"Kolur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod Kumar","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudra Mangesh","family":"Prabhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,5,13]]},"reference":[{"key":"10.25259\/SNI_167_2022\/ref-1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/0019-5413.128747","article-title":"Tubercular spondylitis in children","volume":"48","author":"Jain","year":"2014","journal-title":"Indian J Orthop"},{"key":"10.25259\/SNI_167_2022\/ref-2","doi-asserted-by":"crossref","first-page":"e0123022","DOI":"10.1371\/journal.pone.0123022","article-title":"Comparison of the Japanese orthopaedic association (JOA) score and modified JOA (mJOA) score for the assessment of cervical myelopathy: A multicenter observational study","volume":"10","author":"Kato","year":"2015","journal-title":"PLoS One"},{"key":"10.25259\/SNI_167_2022\/ref-3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13018-018-0732-2","article-title":"Surgical treatment indications and outcomes in patients with spinal metastases in the cervicothoracic junction (CTJ)","volume":"13","author":"Li","year":"2018","journal-title":"J Orthop Surg Res"},{"key":"10.25259\/SNI_167_2022\/ref-4","doi-asserted-by":"crossref","first-page":"400","DOI":"10.2519\/jospt.2009.2930","article-title":"Measurement properties of the neck disability index: A systematic review","volume":"39","author":"Macdelilld","year":"2009","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.25259\/SNI_167_2022\/ref-5","doi-asserted-by":"crossref","first-page":"96S","DOI":"10.1177\/2192568218769053","article-title":"Spinal tuberculosis: Current concepts","volume":"8","author":"Rajasekaran","year":"2018","journal-title":"Glob Spine J"},{"key":"10.25259\/SNI_167_2022\/ref-6","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0028-3886.15067","article-title":"Anterior instrumentation for cervical spine tuberculosis: An analysis of surgical experience with 61 cases","volume":"53","author":"Ramani","year":"2005","journal-title":"Neurol India"},{"key":"10.25259\/SNI_167_2022\/ref-7","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1007\/s11999-016-5133-4","article-title":"Classifications in brief: American spinal injury association (ASIA) impairment scale","volume":"475","author":"Roberts","year":"1999","journal-title":"Clin Orthop Relat Res"},{"key":"10.25259\/SNI_167_2022\/ref-8","doi-asserted-by":"crossref","first-page":"230949902110069","DOI":"10.1177\/23094990211006936","article-title":"Cervical spine TB current concepts in management","volume":"29","author":"Shetty","year":"2021","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"10.25259\/SNI_167_2022\/ref-9","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/BRS.0000000000002371","article-title":"Can C7 slope substitute the T1 slope? An analysis using cervical radiographs and kinematic MRIs","volume":"43","author":"Tamai","year":"2018","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.25259\/SNI_167_2022\/ref-10","first-page":"409","article-title":"The neck disability index: A study of reliability and validity","volume":"14","author":"Vernon","year":"1991","journal-title":"J Manipulative Physiol Ther"},{"key":"10.25259\/SNI_167_2022\/ref-11","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.nec.2007.02.012","article-title":"The cervicothoracic junction","volume":"18","author":"Wang","year":"2007","journal-title":"Neurosurg Clin N Am"},{"key":"10.25259\/SNI_167_2022\/ref-12","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/2192568219846909","article-title":"Can C7 slope be used as a substitute for T1 slope? A radiographic analysis","volume":"10","author":"Ye","year":"2020","journal-title":"Glob Spine J"},{"key":"10.25259\/SNI_167_2022\/ref-13","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1007\/s00264-015-2778-7","article-title":"One-stage combined anterior-posterior approach treatment of multiple cervicothoracic spinal tuberculosis with kyphosis","volume":"39","author":"Zhang","year":"2015","journal-title":"Int Orthop"},{"key":"10.25259\/SNI_167_2022\/ref-14","doi-asserted-by":"crossref","first-page":"e0192581","DOI":"10.1371\/journal.pone.0192581","article-title":"Selection of surgical treatment approaches for cervicothoracic spinal tuberculosis: A 10-year case review","volume":"13","author":"Zhu","year":"2018","journal-title":"PLoS One"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/functional-outcomes-in-the-management-of-cervicothoracic-junction-tuberculosis\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/functional-outcomes-in-the-management-of-cervicothoracic-junction-tuberculosis\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T06:12:38Z","timestamp":1652681558000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/functional-outcomes-in-the-management-of-cervicothoracic-junction-tuberculosis\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,13]]},"references-count":14,"alternative-id":["10.25259\/SNI_167_2022"],"URL":"https:\/\/doi.org\/10.25259\/sni_167_2022","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,13]]},"article-number":"198"}}