{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T13:44:17Z","timestamp":1661521457407},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nMelanocytic schwannomas (MSs) are rare, malignant peripheral nerve sheath tumors with only 200 cases reported to date. These pose imaging and pathological challenges for definitive diagnosis.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA 25-year-old lady presented at our center with a prolonged history of gait disturbance, left ear tinnitus, headaches, and drowsiness. MRI findings showed a midline cystic lesion in the posterior cranial fossa extending caudally to the D1 vertebral body, with marked central hypointensity, and peripheral hyperintensity on T1-weighted images. A suboccipital craniotomy and debulking of the lesion were performed, showing a hyperpigmented, infiltrative tumor adherent to the surrounding structures. This was confirmed as a melanocytic schwannoma on histopathological analysis.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nPosterior fossa MSs involving cervicomedullary region and extending distally to cervicothoracic spinal cord are rare and complex cases, particularly with regard to difficulty diagnosing preoperatively and surgical resection.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_183_2022","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T12:58:00Z","timestamp":1661518680000},"page":"375","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Posterior fossa melanocytic schwannoma extending to the cervicothoracic spinal cord: A clinical rarity"],"prefix":"10.25259","volume":"13","author":[{"given":"Zoha Zahid","family":"Fazal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syeda Maryam","family":"Kazmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Hamza","family":"Bajwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahsan Ali","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"10.25259\/SNI_183_2022\/ref-1","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.5858\/arpa.2017-0162-RA","article-title":"Pathology of melanotic schwannoma","volume":"142","author":"Alexiev","year":"2018","journal-title":"Arch Pathol Lab Med"},{"key":"10.25259\/SNI_183_2022\/ref-2","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/00000478-199003000-00002","article-title":"Psammomatous melanotic schwannoma. A distinctive heritable tumor with special associations including cardiac myxoma and the Cushing syndrome","volume":"14","author":"Carney","year":"1990","journal-title":"Am J Surg Pathol"},{"key":"10.25259\/SNI_183_2022\/ref-3","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.4065\/80.9.1177","article-title":"Diagnosis and treatment of vertebral column metastases","volume":"80","author":"Ecker","year":"2005","journal-title":"Mayo Clin Proc"},{"key":"10.25259\/SNI_183_2022\/ref-4","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.4081\/rt.2012.e3","article-title":"Intramedullary melanotic schwannoma","volume":"4","author":"Hoover","year":"2012","journal-title":"Rare Tumors"},{"key":"10.25259\/SNI_183_2022\/ref-5","first-page":"1807879","article-title":"Melanotic schwannomas are rarely seen pigmented tumors with unpredictable prognosis and challenging diagnosis","volume":"2017","author":"Keskin","year":"2017","journal-title":"Case Rep Pathol"},{"key":"10.25259\/SNI_183_2022\/ref-6","first-page":"319","article-title":"Surgical approach to C1-C2 nerve sheath tumors Neurol India","volume":"52","author":"Krishnan","year":"2004"},{"key":"10.25259\/SNI_183_2022\/ref-7","article-title":"Primary Intraosseous Psammomatous Melanotic Schwannoma of the Sacrum Eurorad Eurorad","year":"2018"},{"key":"10.25259\/SNI_183_2022\/ref-8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/PAS.0b013e3182a0a150","article-title":"Malignant melanotic schwannian tumor: A clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of \u201cmelanotic schwannoma\u201d","volume":"38","author":"Torres-Mora","year":"2014","journal-title":"Am J Surg Pathol"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/posterior-fossa-melanocytic-schwannoma-extending-to-the-cervicothoracic-spinal-cord-a-clinical-rarity\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/posterior-fossa-melanocytic-schwannoma-extending-to-the-cervicothoracic-spinal-cord-a-clinical-rarity\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T12:58:05Z","timestamp":1661518685000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/posterior-fossa-melanocytic-schwannoma-extending-to-the-cervicothoracic-spinal-cord-a-clinical-rarity\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,26]]},"references-count":8,"alternative-id":["10.25259\/SNI_183_2022"],"URL":"https:\/\/doi.org\/10.25259\/sni_183_2022","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,26]]},"article-number":"375"}}