{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T04:24:36Z","timestamp":1727411076052},"reference-count":35,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Background:<\/jats:title>Intracranial hypertension is found in patients with various neurological and neurosurgical conditions such as subarachnoid hemorrhage (more than 50% of the patients have intracranial pressure > 20 mmHg at some point during their hospital stay), traumatic brain injury, and stroke. Various modalities are used to control intracranial hypertension, therapeutic hypothermia is one of them. This systematic review aims to assess the efficacy of therapeutic hypothermia in controlling intracranial hypertension in an adult patient.<\/jats:p><\/jats:sec>Methods:<\/jats:title>A systematic review of the literature published between one patient 1990 and 2020 was conducted. Four databases were searched including CINAHL, PubMed, the Cochrane Library, and EMBASE using keywords traumatic brain injury, intracranial pressure, randomized and controlled trials, and the effect of therapeutic hypothermia on intracranial hypertension.<\/jats:p><\/jats:sec>Results:<\/jats:title>All of the studies included in this review were randomized controlled trials. Most of the studies provided their sample demographics. Sample sizes ranged from 14 to 501. Of the 12 studies, five of them were from the United Kingdom, three of them were from China, two from North America, one from India, and one from Japan.<\/jats:p><\/jats:sec>Conclusion:<\/jats:title>Treating intracranial hypertension with therapeutic hypothermia may be beneficial according to a few studies but it is also associated with many adverse effects. Both the groups suffered from adverse events which were higher in the hypothermic group. However, these adverse events can be managed in any health-care setting. To treat the patients with therapeutic hypothermia, one (the managing team) should be competent enough to manage the adverse effects.<\/jats:p><\/jats:sec>","DOI":"10.25259\/sni_194_2022","type":"journal-article","created":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T09:28:00Z","timestamp":1654248480000},"page":"237","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Systematic review exploring the effect of therapeutic hypothermia on patients with intracranial hypertension"],"prefix":"10.25259","volume":"13","author":[{"given":"Kamlesh","family":"Thakur","sequence":"first","affiliation":[{"name":"Master neurosciences, National Institute of Nursing Education, PGIMER, Chandigarh,"},{"name":"Department of Nursing, Chitkara School of Health Sciences, Chitkara University Punjab, Rajpura, Punjab, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haneet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Master neurosciences, National Institute of Nursing Education, PGIMER, Chandigarh,"},{"name":"Nursing officer, AIIMS, Patna, Bihar,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manju","family":"Dhandapani","sequence":"additional","affiliation":[{"name":"Lecturer, National Institute of Nursing Education, PGIMER, Chandigarh, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teenu","family":"Xavier","sequence":"additional","affiliation":[{"name":"PhD candidate, University of Cincinnati, Cincinnati, Ohio, United States,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganesan","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Clinical Instructor, KGMU College of Nursing, Lucknow, Uttar Pradesh,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laskmanan","family":"Gopichandran","sequence":"additional","affiliation":[{"name":"Associate Professor, College of Nursing, AIIMS, New Delhi,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivashanmugam","family":"Dhandapani","sequence":"additional","affiliation":[{"name":"Professor, Department of Neurosurgery, PGIMER, Chandigarh, India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,6,3]]},"reference":[{"key":"10.25259\/SNI_194_2022\/ref-1","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.3171\/2017.7.FOCUS17426","article-title":"Management of raised intracranial pressure in aneurysmal subarachnoid hemorrhage: Time for a consensus?","volume":"43","author":"Alotaibi","year":"2017","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI_194_2022\/ref-2","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1097\/CCM.0000000000002376","article-title":"Mortality risk stratification after traumatic brain injury and hazard of death with titrated Hypothermia in the eurotherm3235trial","volume":"45","author":"Andrews","year":"2017","journal-title":"Crit Care Med"},{"key":"10.25259\/SNI_194_2022\/ref-3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta22450","article-title":"Therapeutic hypothermia to reduce intracranial pressure after traumatic brain injury: The Eurotherm3235 RCT","volume":"22","author":"Andrews","year":"2018","journal-title":"Health Technol Assess Winch Engl"},{"key":"10.25259\/SNI_194_2022\/ref-4","article-title":"Updated systematic review of therapeutic hypothermia for adult patients following traumatic brain injury. 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