{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T08:28:33Z","timestamp":1723451313935},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nCerebral amyloid angiopathy-related inflammation (CAA-I) presents with slowly progressive nonspecific neurological symptoms, such as headache, cognitive function disorder, and seizures. Pathologically, the deposition of amyloid-\u03b2 proteins at the cortical vascular wall is a characteristic and definitive finding. Differential diagnoses include infectious encephalitis, neurosarcoidosis, primary central nervous system lymphoma, and glioma. Here, we report a case of CAA-I showing acute progression, suggesting a glioma without enhancement, in which a radiological diagnosis was difficult using standard magnetic resonance imaging.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nAn 80-year-old woman was admitted due to transient abnormal behavior. Her initial imaging findings were similar to those of a glioma. She presented with rapid progression of the left hemiplegia and disturbance of consciousness for 6 days after admission and underwent emergent biopsy with a targeted small craniotomy under general anesthesia despite her old age. Intraoperative macroscopic findings followed by a pathological study revealed CAA-I as the definitive diagnosis. Steroid pulse therapy with methylprednisolone followed by oral prednisolone markedly improved both the clinical symptoms and imaging findings.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nDifferential diagnosis between CAA-I and nonenhancing gliomas may be difficult using standard imaging studies in cases presenting with acute progression. A pathological diagnosis under minimally invasive small craniotomy may be an option, even for elderly patients.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_195_2022","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T08:32:24Z","timestamp":1656059544000},"page":"268","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute progression of cerebral amyloid angiopathy-related inflammation diagnosed by biopsy in an elderly patient: A case report"],"prefix":"10.25259","volume":"13","author":[{"given":"Kiyonori","family":"Kuwahara","sequence":"first","affiliation":[{"name":"Department of Comprehensive Strokology, Fujita Health University School of Medicine, Toyoake,"},{"name":"Department of Neurosurgery, Nishichita General Hospital, Tokai,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeta","family":"Moriya","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nishichita General Hospital, Tokai,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Nakahara","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Strokology, Fujita Health University School of Medicine, Toyoake,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Kumai","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine, Toyoake,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine, Toyoake,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuya","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine, Toyoake,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Midoriko","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nishichita General Hospital, Tokai, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikazu","family":"Mizoguchi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Nishichita General Hospital, Tokai, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fujita Health University School of Medicine, Toyoake,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,6,23]]},"reference":[{"key":"10.25259\/SNI_195_2022\/ref-1","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1016\/j.jstrokecerebrovasdis.2015.04.015","article-title":"Cerebral amyloid angiopathy associated with inflammation: report of 3 cases and systematic review","volume":"24","author":"Caldas","year":"2015","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.25259\/SNI_195_2022\/ref-2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1136\/jnnp.2009.204180","article-title":"Cerebral amyloid angiopathy related inflammation: three case reports and a review","volume":"82","author":"Chung","year":"2011","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.25259\/SNI_195_2022\/ref-3","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s11060-020-03474-z","article-title":"Incidence of high grade gliomas presenting as 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