{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T22:14:27Z","timestamp":1781907267622,"version":"3.54.5"},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background:<\/jats:title>\n<jats:p>Fungal cervical spondylodiscitis is rare and accounts for less than 1% of all cervical, thoracic, and lumbar vertebral osteomyelitis and discitis.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description:<\/jats:title>\n<jats:p>A 32-year-old non-immunocompromised male presented with persistent neck pain and paresthesias. The magnetic resonance imaging of the cervical spine demonstrated a contrast-enhancing erosive lesion involving the cervical C6 and C7 vertebral bodies accompanied by epidural phlegmon. Blood culture was negative. The patient underwent a C6 and C7 anterior corpectomy with instrumented fusion (e.g., expandable cage C5 to T1). Intraoperatively, frank pus was noted within the C6-C7 disc space and was accompanied by thick prevertebral and epidural phlegmon extending from C5 to T1. Intraoperative cultures grew <jats:italic>Candida albicans<\/jats:italic>. Three days later, a C6-C7 laminectomy with C4-T2 posterior instrumented fusion was performed; the cultures again grew <jats:italic>C. albicans<\/jats:italic>. The patient was treated with intravenous micafungin for 14 days followed by 6\u201312 months of 400 mg oral fluconazole daily.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>There are few cases in literature where non-immunocompromised patients developed fungal cervical spondylodiscitis. Prompt diagnosis and appropriate management are critical to effectively treat these patients. Surgical intervention may warrant corpectomy, discectomy, and operative debridement followed by long-term targeted antifungal therapy.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_240_2019","type":"journal-article","created":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T11:32:32Z","timestamp":1566732752000},"page":"151","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cervical spondylodiscitis caused by <i>Candida albicans<\/i> in a non-immunocompromised patient: A case report and review of literature"],"prefix":"10.25259","volume":"10","author":[{"given":"Shiwei","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Detroit Medical Center\/Wayne State University School of Medicine, Detroit, Michigan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari D.","family":"Kappel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Detroit Medical Center\/Wayne State University School of Medicine, Detroit, Michigan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Peterson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Detroit Medical Center\/Wayne State University School of Medicine, Detroit, Michigan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parthasarathi","family":"Chamiraju","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Detroit Medical Center\/Wayne State University School of Medicine, Detroit, Michigan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary B.","family":"Rajah","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Detroit Medical Center\/Wayne State University School of Medicine, Detroit, Michigan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc D.","family":"Moisi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Detroit Medical Center\/Wayne State University School of Medicine, Detroit, Michigan,"},{"name":"Seattle Science Foundation, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,8,2]]},"reference":[{"key":"10.25259\/SNI_240_2019\/ref-1","first-page":"e2719","article-title":"Extreme lateral interbody fusion complicated by fungal osteomyelitis: Case report and quick review of the literature","volume":"10","author":"Blecher","year":"2018","journal-title":"Cureus"},{"key":"10.25259\/SNI_240_2019\/ref-2","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jinf.2008.02.005","article-title":"Infectious spondylodiscitis","volume":"56","author":"Cottle","year":"2008","journal-title":"J 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