{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T02:11:23Z","timestamp":1781835083722,"version":"3.54.5"},"reference-count":21,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Cerebral cavernous malformations (CCMs), otherwise known as cavernous hemangiomas\/ cavernomas, are a type of vascular malformation. It is the third most common cerebral vascular malformation, histologically characterized by ectatic, fibrous, blood filled \u201ccaverns\u201d with thin-walled vasculature without intervening normal brain parenchyma.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>Herein, we present a case of an original, spontaneous hemorrhage from a sporadic form of CCM without associated gross developmental venous anomaly in an 11-year-old child, which is an extremely rare occurrence, with the special emphasis on the demographic data of the affected population, risk factors associated with hemorrhage, and correlation of histopathological and radiological findings with an in-depth literature review.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>The significant majority of the CCM are clinically occult. Hence, the development of risk assessment tools and guidelines for timely neurosurgical intervention poses a greater clinical challenge for medical experts rendering the management of the affected individuals with CCM in an anecdotal situation. Presentation of life-threatening rebleeds and neurological deficits in the diagnosed population albeit uncommon is possibly preventable outcomes.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_248_2021","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T13:28:29Z","timestamp":1623072509000},"page":"253","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cerebral cavernous malformation in a child leading to a fatal subarachnoid hemorrhage \u2013 \u201csilent but sinister:\u201d A case report and literature review"],"prefix":"10.25259","volume":"12","author":[{"given":"Pasindu M.","family":"Fernando","sequence":"first","affiliation":[{"name":"Department of Transfusion Medicine, District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. M.","family":"Munasinghe","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. D. C. J. P.","family":"Jayamanne","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. A.","family":"Jayasundara","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. S. N. W. B. M. A. G.","family":"Arambepola","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selliah","family":"Pranavan","sequence":"additional","affiliation":[{"name":"Department of Forensic Pathology District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. D.","family":"Ranathunge","sequence":"additional","affiliation":[{"name":"Department of Pathology, District General Hospital, Mannar, Sri Lanka."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2021,6,7]]},"reference":[{"key":"10.25259\/SNI_248_2021\/ref-1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1227\/NEU.0b013e3181ff9cde","article-title":"Advances in the treatment and outcome of brainstem cavernous malformation surgery: A single-center case series of 300 surgically treated patients","volume":"68","author":"Abla","year":"2011","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_248_2021\/ref-2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1399-0004.2012.01892.x","article-title":"Genetic and cellular basis of cerebral cavernous malformations: Implications for clinical management","volume":"83","author":"Bacigaluppi","year":"2013","journal-title":"Clin 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