{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:22:07Z","timestamp":1777933327330,"version":"3.51.4"},"reference-count":16,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nThis study was to describe the evolution of patients who underwent surgical treatment of drug- resistant occipital lobe epilepsy (OLE) at our institution.<\/jats:p>\n<\/jats:sec>\n\nMethods: <\/jats:title>\nWe performed a retrospective analysis of data collected from electronic and paper clinical records of 20 patients who were diagnosed of OLE and underwent epilepsy surgery at our institution between 1998 and 2018. We also contacted patients by telephone and asked them to fill out a questionnaire about quality of life in epilepsy (QOLIE-10). Assembled data were analyzed using descriptive statistics.<\/jats:p>\n<\/jats:sec>\n\nResults: <\/jats:title>\nThe age at surgery ranged between 19 and 55 years. The period encompassing epilepsy onset and the date of surgery was variable. Semiology of seizures included visual symptoms in 75% of patients. In 90% of cases subdural grids, depth electrodes or a combination of both were used to plan the surgery. The most frequent neuroimaging and histopathological finding was cortical dysplasia (55%). The postoperative follow-up period was up to 15 years. The most common score on the Engel scale was I (70%). Visual deficits increased after surgery. Median score on QOLIE-10 questionnaire was 82.5 (interquartile range: 32.5).<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nSurgical treatment of drug-resistant OLE offers hopeful results to those patients who have run out of pharmacological options and leads to postoperative deficits that are deemed expectable and occasionally acceptable.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_251_2020","type":"journal-article","created":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T05:43:49Z","timestamp":1596260629000},"page":"222","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evolution of patients with surgically treated drug-resistant occipital lobe epilepsy"],"prefix":"10.25259","volume":"11","author":[{"given":"Pablo Barbero","family":"Aznarez","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Jimenez Diaz Foundation University Hospital, Madrid,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta Pastor","family":"Cabeza","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Germans Trias i Pujol Hospital, Badalona, Catalonia, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Sofia Alvarez","family":"Quintana","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jimenez Diaz Foundation University Hospital, Madrid,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Lara-Almunia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jimenez Diaz Foundation University Hospital, Madrid,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio Albisua","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jimenez Diaz Foundation University Hospital, Madrid,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2020,8,1]]},"reference":[{"key":"10.25259\/SNI_251_2020\/ref-1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/ane.12396","article-title":"A comparison of occipital and temporal lobe epilepsies","volume":"132","author":"Appel","year":"2015","journal-title":"Acta Neurol Scand"},{"key":"10.25259\/SNI_251_2020\/ref-2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00415-005-0676-4","article-title":"Retrospective analysis of variables favoring good surgical outcome in posterior epilepsies","volume":"252","author":"Barba","year":"2005","journal-title":"J Neurol"},{"key":"10.25259\/SNI_251_2020\/ref-3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3171\/2012.9.JNS112221","article-title":"Occipitotemporal hippocampal depth electrodes in intracranial epilepsy monitoring: Safety and utility","volume":"118","author":"Bekelis","year":"2013","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_251_2020\/ref-4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3171\/JNS\/2008\/109\/7\/0057","article-title":"Surgical treatment of occipital lobe epilepsy","volume":"109","author":"Binder","year":"2008","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_251_2020\/ref-5","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.4103\/0028-3886.246263","article-title":"Epilepsy surgery for focal cortical dysplasia: Seizure and quality of life (QOLIE-89) outcomes","volume":"66","author":"Chaturvedi","year":"2018","journal-title":"Neurol India"},{"key":"10.25259\/SNI_251_2020\/ref-6","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1111\/j.1528-1167.2005.70904.x","article-title":"Clinical features of patients with posterior cortex epilepsies and predictors of surgical outcome","volume":"46","author":"Dalmagro","year":"2005","journal-title":"Epilepsia"},{"key":"10.25259\/SNI_251_2020\/ref-7","first-page":"609","article-title":"Outcome with respect to epileptic seizures","volume-title":"Surgical Treatment of Epilepsies","author":"Engel","year":"1993"},{"key":"10.25259\/SNI_251_2020\/ref-8","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1093\/neuros\/nyx158","article-title":"Seizure outcomes in occipital lobe and posterior quadrant epilepsy surgery: A systematic review and meta-analysis","volume":"82","author":"Harward","year":"2017","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_251_2020\/ref-9","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3171\/2017.5.JNS162963","article-title":"Relationship between cortical resection and visual function after occipital lobe epilepsy surgery","volume":"129","author":"Heo","year":"2017","journal-title":"J 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Med"},{"key":"10.25259\/SNI_251_2020\/ref-13","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.yebeh.2016.06.014","article-title":"Occipital and occipital plus epilepsies: A study of involved epileptogenic networks through EEG quantification","volume":"62","author":"Marchi","year":"2016","journal-title":"Epilepsy Behav"},{"key":"10.25259\/SNI_251_2020\/ref-14","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/epi.13709","article-title":"ILAE classification of the epilepsies: Position paper of the ILAE commission for classification and terminology","volume":"58","author":"Scheffer","year":"2017","journal-title":"Epilepsia"},{"key":"10.25259\/SNI_251_2020\/ref-15","first-page":"157","article-title":"Validation of the Spanish version of the QOLIE-10 quality of life in epilepsy 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