{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T23:33:56Z","timestamp":1784849636996,"version":"3.55.0"},"reference-count":25,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nChemotherapy-induced peripheral neuropathy (CIPN) is one of the most common persistent adverse effects of chemotherapy affecting cancer survivors. Other than the use of duloxetine, no other intervention has a proven benefit for these patients. Here, a patient with multiple myeloma who developed CIPN experienced a significant reduction in their symptoms after the implantation of a spinal cord stimulator.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA 64-year-old male with a history of multiple myeloma presented with chronic pain 4 years after chemotherapy, followed by an autologous stem cell transplant. As the patient\u2019s symptoms were refractory to medical management, he underwent placement of a permanent spinal cord stimulator, resulting in 80% relief of calf pain and a 60% improvement in foot paresthesias\/pain.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nSpinal cord stimulation proved effective in treating CIPN (CIPN following autologous stem cell transplant) in a 64-year-old male treated 4 years ago for multiple myeloma.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_284_2025","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T06:42:54Z","timestamp":1749192174000},"page":"222","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["BurstDR\u2122 spinal cord stimulation for chemotherapy-induced peripheral neuropathy"],"prefix":"10.25259","volume":"16","author":[{"given":"Stephen","family":"Jaffee","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyothika","family":"Mamagdi","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Vaezi","sequence":"additional","affiliation":[{"name":"Department of Pain Medicine, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trent","family":"Kite","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavika","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Valleta","sequence":"additional","affiliation":[{"name":"Department of Pain Medicine, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feno","family":"Monaco","sequence":"additional","affiliation":[{"name":"Department of Pain Medicine, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestor","family":"Tomycz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Allegheny Health Network, Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2025,6,6]]},"reference":[{"key":"10.25259\/SNI_284_2025\/ref-1","first-page":"223","article-title":"Spinal cord stimulator for treating chemotherapy-induced peripheral neuropathy","volume":"5","author":"Abd-Elsayed","year":"2021","journal-title":"Pain Med Case Rep"},{"key":"10.25259\/SNI_284_2025\/ref-2","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jclinane.2015.08.011","article-title":"Efficacy of spinal cord stimulators in treating peripheral neuropathy: A case series","volume":"28","author":"Abd-Elsayed","year":"2016","journal-title":"J Clin Anesth"},{"key":"10.25259\/SNI_284_2025\/ref-3","first-page":"41","article-title":"Management of chronic chemotherapy induced peripheral neuropathy using neurostimulation","volume-title":"Proceedings of the regional anesthesia and pain medicine conference: 14th annual pain medicine meeting of the American society of regional anesthesia and pain medicine Miami Beach","author":"Abd-Elsayed","year":"2015"},{"key":"10.25259\/SNI_284_2025\/ref-4","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1590\/S0034-70942007000500008","article-title":"Spinal cord stimulation in the treatment of refractory painful chemotherapy induced polyneuropathy","volume":"57","author":"Braun Filho","year":"2007","journal-title":"Rev Bras Anestesiol"},{"key":"10.25259\/SNI_284_2025\/ref-5","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s40487-021-00168-y","article-title":"Chemotherapy-induced peripheral neuropathy: Epidemiology, pathomechanisms and treatment","volume":"9","author":"Burgess","year":"2021","journal-title":"Oncol Ther"},{"key":"10.25259\/SNI_284_2025\/ref-6","first-page":"732","article-title":"Peripheral neuropathy: Evaluation and differential diagnosis","volume":"102","author":"Castelli","year":"2020","journal-title":"Am Fam Phys"},{"key":"10.25259\/SNI_284_2025\/ref-7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jpainsymman.2003.05.007","article-title":"Spinal cord stimulation relieves chemotherapy-induced pain: A clinical case report","volume":"27","author":"Cata","year":"2004","journal-title":"J Pain Symptom Manage"},{"key":"10.25259\/SNI_284_2025\/ref-8","first-page":"S271","article-title":"Chemotherapy-induced peripheral neuropathy pain and postmastectomy pain syndrome in a breast cancer patient managed with neurostimulation: A case report","volume":"9","author":"Chai","year":"2017","journal-title":"PMR"},{"key":"10.25259\/SNI_284_2025\/ref-9","first-page":"S138","article-title":"Dual coverage of metastatic ostealgia and cancer-related peripheral neuropathy with a spinal cord stimulator","volume":"11","author":"Grant","year":"2019","journal-title":"PMR"},{"key":"10.25259\/SNI_284_2025\/ref-10","doi-asserted-by":"crossref","first-page":"291","DOI":"10.36076\/pmcr.2021.5.291","article-title":"Improvement in neuropathic pain, proprioception, and gait stability after spinal cord stimulator implantation for chemotherapy-induced peripheral neuropathy","volume":"5","author":"Kamdar","year":"2021","journal-title":"Pain Med Case Rep"},{"key":"10.25259\/SNI_284_2025\/ref-11","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1093\/pm\/pnz003","article-title":"Burst spinal cord stimulation: A clinical review","volume":"20","author":"Kirketeig","year":"2019","journal-title":"Pain Med"},{"key":"10.25259\/SNI_284_2025\/ref-12","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1055\/s-0040-1709985","article-title":"Spinal cord stimulation as a treatment option for refractory chemotherapy-induced peripheral neuropathy: Case report","volume":"39","author":"Lopes","year":"2020","journal-title":"Arq Bras Neurocir"},{"key":"10.25259\/SNI_284_2025\/ref-13","first-page":"991","article-title":"Chemotherapy-induced peripheral neuropathy: A recent update on pathophysiology and treatment","volume":"14","author":"Mattar","year":"2024","journal-title":"Life (Basel)"},{"key":"10.25259\/SNI_284_2025\/ref-14","first-page":"e84","article-title":"Chronic regional pain syndrome and chemotherapy-induced peripheral neuropathy in a patient with metastatic melanoma","volume":"23","author":"Michael","year":"2020","journal-title":"Neuromod Technol Neural Interface"},{"key":"10.25259\/SNI_284_2025\/ref-15","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1182\/bloodadvances.2019000524","article-title":"Long-term outcomes after autologous stem cell transplantation for multiple myeloma","volume":"4","author":"Nishimura","year":"2020","journal-title":"Blood Adv"},{"key":"10.25259\/SNI_284_2025\/ref-16","first-page":"e147","article-title":"Treatment of lower extremities chemotherapy induced allodynia and neuropathic pain with wireless scs: Case study (10693)","volume":"19","author":"Panchal","year":"2016","journal-title":"Neuromod Technol Neural Interface"},{"key":"10.25259\/SNI_284_2025\/ref-17","first-page":"e69","article-title":"High frequency spinal cord stimulation for neuropathic pain capturing bilateral hands and feet without paresthesia","volume":"22","author":"Sarkar","year":"2019","journal-title":"Neuromod Technol Neural Interface"},{"key":"10.25259\/SNI_284_2025\/ref-18","first-page":"e80","article-title":"The increasing utility of spinal cord stimulation for cancer related pain: A case series","volume":"18","author":"Sayed","year":"2015","journal-title":"Neuromod Technol Neural Interface"},{"key":"10.25259\/SNI_284_2025\/ref-19","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1016\/j.pain.2014.09.020","article-title":"Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis","volume":"155","author":"Seretny","year":"2014","journal-title":"Pain"},{"key":"10.25259\/SNI_284_2025\/ref-20","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3322\/caac.21820","article-title":"Cancer statistics 2024","volume":"74","author":"Siegel","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"10.25259\/SNI_284_2025\/ref-21","first-page":"e243","article-title":"Three cases of high-frequency spinal cord stimulation for painful lower extremity neuropathy of varied etiologies","volume":"20","author":"Sisson","year":"2017","journal-title":"Neuromod Technol Neural Interface"},{"key":"10.25259\/SNI_284_2025\/ref-22","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1002\/ana.24951","article-title":"Chemotherapy-induced peripheral neuropathy: A current review","volume":"81","author":"Staff","year":"2017","journal-title":"Ann Neurol"},{"key":"10.25259\/SNI_284_2025\/ref-23","first-page":"e7","article-title":"Opioid discontinuation following successful treatment of chemotherapy-induced peripheral neuropathy with dorsal column spinal cord stimulation","volume":"24","author":"Wright","year":"2021","journal-title":"Neuromod Technol Neural Interface"},{"key":"10.25259\/SNI_284_2025\/ref-24","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.3390\/ijms20061451","article-title":"Mechanisms of chemotherapy-induced peripheral neuropathy","volume":"20","author":"Zajaczkowska","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.25259\/SNI_284_2025\/ref-25","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s10549-020-06079-2","article-title":"Characterization of chemotherapy-induced peripheral neuropathy using patient-reported outcomes and quantitative sensory testing","volume":"186","author":"Zhi","year":"2021","journal-title":"Breast Cancer Res Treat"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/burstdr-spinal-cord-stimulation-for-chemotherapy-induced-peripheral-neuropathy\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/burstdr-spinal-cord-stimulation-for-chemotherapy-induced-peripheral-neuropathy\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T06:42:59Z","timestamp":1749192179000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/burstdr-spinal-cord-stimulation-for-chemotherapy-induced-peripheral-neuropathy\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,6]]},"references-count":25,"alternative-id":["10.25259\/SNI_284_2025"],"URL":"https:\/\/doi.org\/10.25259\/sni_284_2025","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,6]]},"article-number":"222"}}