{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:56:26Z","timestamp":1787025386361,"version":"build-2736575974"},"reference-count":19,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Chronic subdural hematoma (CSDH) is a condition that tends to recur frequently. Although middle meningeal artery embolization (MMAE) is an effective CSDH treatment, there is currently no consensus regarding the optimal timing for embolization.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n In this single-center and retrospective study, we reviewed 72 cases with 1\n st<\/jats:sup>\n -time recurrent CSDH from January 2018 to July 2023 and identified those treated with MMAE to examine its effect and the impact of differences in the timing of treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Of the 72 cases with CSDH recurrence for the 1\n st<\/jats:sup>\n time (mean age: 80.4 \u00b1 9.7 years; men: 62 [86.1%]; mean first recurrence interval: 33 \u00b1 24 days), 27 (37.5%) experienced a second recurrence. The mean first recurrence interval was shorter in cases with a second recurrence compared to cured cases: 24.3 \u00b1 18.6 versus 38.3 \u00b1 25.6 days, respectively (\n P<\/jats:italic>\n = 0.005). MMAE was performed in 17 (23.6%) cases (mean age: 82 \u00b1 6.2 years; men: 14 [82.4%]). The mean time from initial surgical treatment to embolization was 52.4 \u00b1 35.4 days, and the mean recurrence interval before MMAE was 24.9 \u00b1 19.6 days. Six cases (35.3%) experienced post-embolization recurrence and required surgical treatment. The mean recurrence interval before MMAE was shorter in cases with recurrence after MMAE (15 \u00b1 6.4 vs. 30 \u00b1 22.1 days,\n P<\/jats:italic>\n = 0.023). The time from initial surgical treatment to embolization was significantly shorter: 31.3 \u00b1 12.8 versus 63.9 \u00b1 38.9 days (\n P<\/jats:italic>\n = 0.039).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Cases with a short first recurrence interval were more likely to experience a second recurrence. Repeated recurrences within a short time increased the likelihood of post-embolization recurrence. MMAE performed early following the initial surgical treatment increased the recurrence risk.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_293_2024","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T04:05:20Z","timestamp":1718942720000},"page":"214","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Timing of chronic subdural hematoma treatment affects middle meningeal artery embolization outcome"],"prefix":"10.25259","volume":"15","author":[{"given":"Naoya","family":"Imai","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Minokamo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Daiyukai General Hospital, Ichinomiya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Hospital Organization Toyohashi Medical Center, Toyohashi, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Morishima","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Daiyukai General Hospital, Ichinomiya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuki","family":"Aki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Daiyukai General Hospital, Ichinomiya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-ichi","family":"Shirakami","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Daiyukai General Hospital, Ichinomiya, 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