{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:06:21Z","timestamp":1780056381236,"version":"3.54.0"},"reference-count":5,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Kartagener syndrome (KS), a phenotypic subset of primary ciliary dyskinesia, is characterized by defective motile cilia, impaired mucociliary clearance, chronic sinus disease, bronchiectasis, and situs abnormalities. Although respiratory manifestations predominate, central nervous system complications such as brain abscess are rare but potentially life-threatening. Because early neurological manifestations may be focal and non-specific, diagnosis can be delayed when symptoms are initially attributed to cervical or peripheral pathology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Case description:<\/jats:title>\n                    <jats:p>\n                      We describe a 27-year-old male with known KS who developed a right frontal brain abscess initially misattributed to presumed cervical pathology. The patient presented with progressive left upper extremity weakness and numbness, initially managed as presumed cervical pathology. Approximately 1 month later, he was admitted after generalized tonic\u2013clonic seizures. Initial laboratory evaluation showed leukocytosis with neutrophilia, with a white blood cell count of 14.22 \u00d7 10\n                      <jats:sup>9<\/jats:sup>\n                      \/L and an absolute neutrophil count of 12.05 \u00d7 10\n                      <jats:sup>9<\/jats:sup>\n                      \/L (84.6%), together with hemoglobin of 21.6 g\/dL, hematocrit of 70.6%, C-reactive protein of 1.0 mg\/L, erythrocyte sedimentation rate of 1 mm\/h, and negative human immunodeficiency virus serology. Brain magnetic resonance imaging revealed a ring-enhancing lesion in the right frontal lobe with diffusion restriction, consistent with abscess formation. The patient initially received intravenous meropenem 2 g every 8 h. Right frontal abscess drainage was performed on May 10, 2024; intraoperative cultures showed no growth. Meropenem was continued for a documented 21-day inpatient course, and intravenous vancomycin 1 g every 12 h was added for the final 4 inpatient days. The patient achieved complete neurological recovery, and postoperative imaging demonstrated marked radiological improvement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights a diagnostic pitfall in patients with KS presenting with focal neurological symptoms. Progressive unilateral weakness should prompt early cranial imaging, even when the initial clinical picture appears compatible with cervical pathology. Early recognition, timely drainage, and adequately documented antimicrobial management are essential to prevent morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/sni_317_2026","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T11:19:53Z","timestamp":1780053593000},"page":"321","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic pitfall: Right frontal brain abscess presenting as presumed cervical pathology in a patient with Kartagener syndrome - A case report"],"prefix":"10.25259","volume":"17","author":[{"given":"Baris","family":"Yasar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed Yusuf","family":"Hamurcu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Kavcar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atakan","family":"Besnek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inan","family":"Uzunoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"key":"10.25259\/SNI_317_2026\/ref-1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.cmi.2023.08.016","article-title":"European society of clinical microbiology and infectious diseases guidelines on diagnosis and treatment of brain abscess in children and adults","volume":"30","author":"Bodilsen","year":"2024","journal-title":"Clin Microbiol Infect"},{"key":"10.25259\/SNI_317_2026\/ref-2","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1136\/adc.2006.096958","article-title":"Primary ciliary dyskinesia: Current state of the art","volume":"92","author":"Bush","year":"2007","journal-title":"Arch Dis Child"},{"key":"10.25259\/SNI_317_2026\/ref-3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0303-8467(91)90102-U","article-title":"Palinopsia: Unusual presenting symptom of a cerebral abscess in a man with Kartagener\u2019s syndrome","volume":"93","author":"Lunardi","year":"1991","journal-title":"Clin Neurol Neurosurg"},{"key":"10.25259\/SNI_317_2026\/ref-4","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1080\/02699050902973921","article-title":"False localizing signs in traumatic brain injury","volume":"23","author":"McKenna","year":"2009","journal-title":"Brain Inj"},{"key":"10.25259\/SNI_317_2026\/ref-5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/ppul.23304","article-title":"Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations","volume":"51","author":"Shapiro","year":"2016","journal-title":"Pediatr Pulmonol"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/diagnostic-pitfall-right-frontal-brain-abscess-presenting-as-presumed-cervical-pathology-in-a-patient-with-kartagener-syndrome-a-case-report\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/diagnostic-pitfall-right-frontal-brain-abscess-presenting-as-presumed-cervical-pathology-in-a-patient-with-kartagener-syndrome-a-case-report\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T11:19:54Z","timestamp":1780053594000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/diagnostic-pitfall-right-frontal-brain-abscess-presenting-as-presumed-cervical-pathology-in-a-patient-with-kartagener-syndrome-a-case-report\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,29]]},"references-count":5,"alternative-id":["10.25259\/SNI_317_2026"],"URL":"https:\/\/doi.org\/10.25259\/sni_317_2026","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,29]]},"article-number":"321"}}