{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:03:35Z","timestamp":1788314615124,"version":"build-2803163510"},"reference-count":12,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nWe analyzed the role of hypoalbuminemia, dialysis, and other risk factors that increase morbidity\/ mortality following surgery for primary pyogenic spinal infections (PSIs). The American College of Surgeons\u2019 National Surgical Quality Improvement Program (ACS-NSQIP) that included 627 patients was utilized as our database.<\/jats:p>\n<\/jats:sec>\n\nMethods: <\/jats:title>\nPrimary spinal surgery for spondylodiscitis was evaluated in a ACS-NSQIP database involving 627 patients between 2010 and 2019. Outcome assessment included evaluation of 30-day postoperative morbidity, and mortality rates.<\/jats:p>\n<\/jats:sec>\n\nResults: <\/jats:title>\nWithin 30 postoperative days, complications occurred in 14.6% (92\/627) of patients; 59 (9.4%) required readmission, and 39 (6.2%) required additional surgery. The most common complications were: wound infections, pneumonia, septic shock, and death (1.8%). Hypoalbuminemia (i.e., significantly associated with unplanned readmission and reoperation), and dialysis were the two major risk factors contributing to increased perioperative morbidity and mortality.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nAmong 627 ACS-NSQIP patients undergoing primary surgery for PSIs, hypoalbuminemia and dialysis were associated with higher risks of major perioperative morbidity (i.e., within 30 postoperative days \u2013 mostly readmissions and reoperations) and mortality.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_330_2022","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T11:54:32Z","timestamp":1651838072000},"page":"193","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Preoperative hypoalbuminemia and dialysis increase morbidity\/mortality after spine surgery for primary pyogenic spinal infections (ACS-NSQIP Study)"],"prefix":"10.25259","volume":"13","author":[{"given":"Gaston","family":"Camino-Willhuber","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Institute of Orthopedics \u201cCarlos E. Ottolenghi,\u201d Hospital Italiano de Buenos Aires, Buenos Aires, Argentina,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin","family":"Franklin","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California Irvine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Rosecrance","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California Irvine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Oyadomari","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California Irvine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of California Irvine, Orange, California, United States,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Holc","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Institute of Orthopedics \u201cCarlos E. Ottolenghi,\u201d Hospital Italiano de Buenos Aires, Buenos Aires, Argentina,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sohaib","family":"Hashmi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of California Irvine, Orange, California, United States,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California Irvine, Orange, California, United States,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of California Irvine, Orange, California, United States,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Emmerich","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Children\u2019s Hospital La Plata, La Plata, Argentina."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Po","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of California Irvine, Orange, California, United States,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,5,6]]},"reference":[{"key":"10.25259\/SNI_330_2022\/ref-1","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1097\/BRS.0000000000000450","article-title":"Preoperative serum albumin level as a predictor of postoperative complication after spine fusion","volume":"39","author":"Adogwa","year":"2014","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.25259\/SNI_330_2022\/ref-2","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1097\/BRS.0000000000001591","article-title":"Malnutrition predicts infectious and wound complications following posterior lumbar spinal 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