{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:53:49Z","timestamp":1790610829728,"version":"4.1.0"},"reference-count":16,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Cauda equina syndromes (CESs) due to leptomeningeal metastases from primitive lung tumors are rare. Despite recent advancements in neuro-oncology and molecular biology, the prognosis for these patients remains poor. Here, we present a case in which a patient developed lumbar leptomeningeal metastases from lung carcinoma that contributed to a CES and reviewed the appropriate literature.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 55-year-old female presented with the left lower extremity sciatica\/weakness. Two years ago, a then 53-year-old female had received Gamma Knife stereotactic radiosurgery (SRS) for a cerebellopontine angle schwannoma. Recently, she underwent resection of lung carcinoma and SRS for a right hemispheric cerebellar metastasis. Now at age 55, she presented with the left lower extremity sciatica\/weakness. When her new lumbar MR was interpreted as showing a L5 schwannoma, a L4-L5 laminectomy was performed at surgery, the authors encountered multifocal leptomeningeal metastases densely infiltrating the cauda equina. Although only subtotal resection\/decompression of tumor was feasible, she did well for the ensuing year. The histological diagnosis confirmed the lesion to be a poorly differentiated lung adenocarcinoma.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Patients with a history of prior metastatic lung cancer may present with spinal leptomeningeal metastases resulting in a CES.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_365_2020","type":"journal-article","created":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T05:44:03Z","timestamp":1596260643000},"page":"225","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cauda equina syndrome caused by lumbar leptomeningeal metastases from lung adenocarcinoma mimicking a schwannoma"],"prefix":"10.25259","volume":"11","author":[{"given":"Giovanni Federico","family":"Nicoletti","sequence":"first","affiliation":[{"name":"Neurosurgery Unit, Highly Specialized Hospital and of National Importance \u201cGaribaldi,\u201d Piazza Santa Maria di Ges\u00f9 5, Catania, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Emmanuele","family":"Umana","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cannizzaro Hospital, Via Messina 829, Catania, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Graziano","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Highly Specialized Hospital and of National Importance \u201cGaribaldi,\u201d Piazza Santa Maria di Ges\u00f9 5, Catania, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Cal\u00ec","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Highly Specialized Hospital and of National Importance \u201cGaribaldi,\u201d Piazza Santa Maria di Ges\u00f9 5, Catania, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Fricia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cannizzaro Hospital, Via Messina 829, Catania, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Cicero","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cannizzaro Hospital, Via Messina 829, Catania, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Scalia","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Highly Specialized Hospital and of National Importance \u201cGaribaldi,\u201d Piazza Santa Maria di Ges\u00f9 5, Catania, 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