{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:01:52Z","timestamp":1771657312823,"version":"3.50.1"},"reference-count":12,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nDisseminated histoplasmosis involving the central nervous system occurs in 5\u201310% of cases. However, intramedullary spinal cord lesions are extremely rare. Here, 45-year-old female with a T8\u20139 intramedullary lesion did well following surgical extirpation.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nFor 2 weeks, a 45-year-old female experienced progressive lower back pain, paresthesias, and paraparesis. The magnetic resonance imaging showed an intramedullary expansive lesion at the T8\u2013T9 level that markedly enhanced with contrast. Surgery, consisting of T8\u2013T10 laminectomies performed using neuronavigation, an operating microscope, and intraoperative monitoring, revealed a well-demarcated lesion that proved to be a focus of histoplasmosis; it was readily completely excised.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nSurgery is the gold standard for treating spinal cord compression attributed to intramedullary histoplasmosis unresponsive to medical management.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_399_2023","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T18:18:40Z","timestamp":1686334720000},"page":"197","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Intramedullary histoplasmosis of the thoracic cord as an isolated lesion: A rare case report and literature review"],"prefix":"10.25259","volume":"14","author":[{"given":"Eduardo Cattapan","family":"Piovesan","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Passo Fundo, Passo Fundo, Rio Grande do Sul, Brazil,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner Petry","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S\u00e3o Vicente de Paulo Hospital, Passo Fundo, Rio Grande do Sul, Brazil,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adroaldo Baseggio","family":"Mallmann","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, S\u00e3o Vicente de Paulo Hospital, Passo Fundo, Rio Grande do Sul, Brazil,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo Jos\u00e9","family":"Guiroy","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Cl\u00ednica de Cuyo, Mendoza, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles Andr\u00e9","family":"Carazzo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Passo Fundo, Passo Fundo, Rio Grande do Sul, Brazil,"},{"name":"Department of Neurosurgery, S\u00e3o Vicente de Paulo Hospital, Passo Fundo, Rio Grande do Sul, Brazil,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"10.25259\/SNI_399_2023\/ref-1","first-page":"e4238","article-title":"Disseminated central nervous system histoplasmosis: A case report","volume":"11","author":"Gonzalez","year":"2019","journal-title":"Cureus"},{"key":"10.25259\/SNI_399_2023\/ref-2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1055\/s-0035-1554932","article-title":"Histoplasmosis with deep CNS involvement: Case presentation with discussion and literature review","volume":"76","author":"Hariri","year":"2015","journal-title":"J Neurol Surg Rep"},{"key":"10.25259\/SNI_399_2023\/ref-3","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00024720-200304000-00016","article-title":"Intramedullary histoplasmosis spinal cord abscess in a nonendemic region: Case report and review of the literature","volume":"16","author":"Hott","year":"2003","journal-title":"J Spinal Disord Tech"},{"key":"10.25259\/SNI_399_2023\/ref-4","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1227\/01.NEU.0000245583.08532.35","article-title":"Spinal intramedullary histoplasmosis as the initial presentation of human immunodeficiency virus infection: case report","volume":"59","author":"Manning","year":"2006","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_399_2023\/ref-5","first-page":"109","article-title":"Intramedullary spinal cord compression caused by Histoplasma capsulatum A case report and meta-analysis","volume":"4","author":"N\u2019dri-Oka","year":"2015","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_399_2023\/ref-6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.25259\/SNI_345_2021","article-title":"Indolent nonendemic central nervous system histoplasmosis presenting as an isolated intramedullary enhancing spinal cord lesion","volume":"12","author":"Recker","year":"2021","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_399_2023\/ref-7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.25259\/SNI_1064_2021","article-title":"Intramedullary histoplasmosis lesion in children: A case report","volume":"13","author":"Renan","year":"2022","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_399_2023\/ref-8","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3390\/jof5030070","article-title":"Central nervous system infection with Histoplasma capsulatum","volume":"5","author":"Riddell","year":"2019","journal-title":"J Fungi 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(Baltimore)"},{"key":"10.25259\/SNI_399_2023\/ref-12","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1086\/427880","article-title":"Diagnosis and management of central nervous system histoplasmosis","volume":"40","author":"Wheat","year":"2005","journal-title":"Clin Infect Dis"}],"container-title":["Surgical Neurology 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