{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T23:30:27Z","timestamp":1768347027993,"version":"3.49.0"},"reference-count":23,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Rosai-Dorfman disease (RDD) is a rare type of histiocytosis that can manifest with diverse symptoms. It usually presents with systemic involvement, and only a few cases have been reported at the level of the skull base. RDD typically follows a benign course during the progression of the disease. In this particular case reported, after the skull base invasion, the disease started to infiltrate the brain parenchyma. Our objective for this case report was to present this particular progression pattern and the nuances of its surgical treatment. In addition, a revision of the current literature was performed about skull base RDD with intracranial invasion and brain parenchyma infiltration not previously described.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>We are presenting the case study of a 57-year-old male patient who was experiencing severe headaches and an increase in volume in the right fronto-orbital region. On clinical examination, no neurologic clinical symptoms were observed. Contrast computed tomography and magnetic resonance imaging showed a tumor mass that affected the right orbit, frontal paranasal sinus, greater sphenoid wing, and right frontal lobe with moderate adjacent brain edema. The patient underwent surgery using an extended pterional approach with intracranial, orbital decompression, and frontal sinus cranialization, accompanied by frontal lobe tumor resection. Neuropathologic diagnosis revealed a Rosai-Dorfman histiocytosis disease.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>The etiopathogenesis of RDD is still not completely understood. The current literature considers this disease to have a predominantly benign course. Nevertheless, as we have shown in this case, it may, in some cases, present direct parenchymal invasion. We consider that prompt surgical treatment should be ideal to avoid the local and systemic progression of the disease.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_405_2024","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T06:47:24Z","timestamp":1726814844000},"page":"337","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rosai-Dorfman sphenoorbital histiocytosis with intraparenchymal invasion: Do we have to consider this skull base pathology as a malignant disease?"],"prefix":"10.25259","volume":"15","author":[{"given":"Erik","family":"Burgos-Sosa","sequence":"first","affiliation":[{"name":"Center for Cranial Base Surgery, Hospital Angeles Pedregal, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose de Jesus Julian","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Center for Cranial Base Surgery, Hospital Angeles Pedregal, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Chavez-Macias","sequence":"additional","affiliation":[{"name":"Department of Neuropathology, Hospital General de Mexico, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Pablo","family":"Ichazo-Castellanos","sequence":"additional","affiliation":[{"name":"Center for Cranial Base Surgery, Hospital Angeles Pedregal, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Antonio Garfias","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Center for Cranial Base Surgery, Hospital Angeles Pedregal, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berenice","family":"Garcia-Guzman","sequence":"additional","affiliation":[{"name":"Center for Cranial Base Surgery, Hospital Angeles Pedregal, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agustin","family":"Dorantes-Argandar","sequence":"additional","affiliation":[{"name":"Center for Cranial Base Surgery, Hospital Angeles Pedregal, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"key":"10.25259\/SNI_405_2024\/ref-1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4103\/JMAU.JMAU_45_18","article-title":"Orbital Rosai-Dorfman disease: A case report and literature review","volume":"7","author":"Al-Maghrabi","year":"2019","journal-title":"J Microsc Ultrastruct"},{"key":"10.25259\/SNI_405_2024\/ref-2","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/modpathol.3880278","article-title":"Rosai-Dorfman disease isolated to the central nervous system: A report of 11 cases","volume":"14","author":"Andriko","year":"2001","journal-title":"Mod Pathol"},{"key":"10.25259\/SNI_405_2024\/ref-3","doi-asserted-by":"crossref","first-page":"E22","DOI":"10.1093\/ons\/opaa261","article-title":"Morphometric comparison of the pterional trans-sylvian and the pretemporal trans-clinoidal approaches to the posterior communicating artery","volume":"20","author":"Basma","year":"2020","journal-title":"Oper Neurosurg (Hagerstown)"},{"key":"10.25259\/SNI_405_2024\/ref-4","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1136\/jclinpath-2020-206733","article-title":"Rosai-Dorfman disease: An overview","volume":"73","author":"Bruce-Brand","year":"2020","journal-title":"J Clin Pathol"},{"key":"10.25259\/SNI_405_2024\/ref-5","doi-asserted-by":"crossref","first-page":"e351","DOI":"10.1016\/j.wneu.2023.02.051","article-title":"RosaiDorfman disease in the skull base: A case series study","volume":"173","author":"Cao","year":"2023","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_405_2024\/ref-6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s00066-009-1911-1","article-title":"Stereotactic interstitial radiosurgery for intracranial RosaiDorfman disease. 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