{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T01:48:22Z","timestamp":1749692902044},"reference-count":40,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\"><jats:title>Background:<\/jats:title><jats:p>The aim of the study was to characterize the clinical profile of patients with anterior communicating artery (ACoA) aneurysms and examine potential correlations between clinical findings, aneurysm morphology, and outcome.<\/jats:p><\/jats:sec><jats:sec id=\"st2\"><jats:title>Methods:<\/jats:title><jats:p>A review of medical records and diagnostic neuroimaging reports of patients treated at a neurosurgical service in Porto Alegre, Brazil, between August 2008 and January 2015 was performed.<\/jats:p><\/jats:sec><jats:sec id=\"st3\"><jats:title>Results:<\/jats:title><jats:p>During the period, 100 patients underwent surgery for ACoA aneurysms. Fifteen had unruptured aneurysms and 85 had ruptured aneurysms. Ruptured aneurysms had a higher aspect ratio than unruptured ones (2.37 \u00b1 0.71 vs. 1.93 \u00b1 0.51,<jats:italic>P<\/jats:italic>= 0.02). Intraoperative rupture occurred in 3%, and temporary clipping was performed in 15%. Clinical vasospasm occurred in 43 patients with ruptured aneurysms (50.6%). Overall, mortality was 26%; 25 patients in the ruptured group (29.4%) and one in the unruptured group (6%). The Glasgow Outcome Scale (GOS) was favorable (GOS 4 or 5) in 54% of patients, significantly more so in those with unruptured aneurysms (<jats:italic>P<\/jats:italic>= 0.01). In patients with ruptured aneurysms, mortality was associated with preoperative Hunt and Hess (HH) score (<jats:italic>P<\/jats:italic>&lt; 0.001), hydrocephalus (<jats:italic>P<\/jats:italic>&lt; 0.001), and clinical complications (<jats:italic>P<\/jats:italic>&lt; 0.001). Unfavorable outcomes were associated with HH score (<jats:italic>P<\/jats:italic>&lt; 0.001), Fisher grade (<jats:italic>P<\/jats:italic>= 0.015), clinical vasospasm (<jats:italic>P<\/jats:italic>= 0.012), external ventricular drain (<jats:italic>P<\/jats:italic>= 0.015), hydrocephalus (<jats:italic>P<\/jats:italic>&lt; 0.001), and presence of clinical complications (<jats:italic>P<\/jats:italic>= 0.001). In patients with unruptured aneurysms, presence of clinical complications was the only factor associated with mortality (<jats:italic>P<\/jats:italic>&lt; 0.001).<\/jats:p><\/jats:sec><jats:sec id=\"st4\"><jats:title>Conclusion:<\/jats:title><jats:p>Despite advances in the management of subarachnoid hemorrhage and surgical treatment of aneurysms, mortality is still high, especially due to clinical complications.<\/jats:p><\/jats:sec>","DOI":"10.25259\/sni_41_2019","type":"journal-article","created":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T14:06:05Z","timestamp":1570197965000},"page":"193","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical and morphological profile of aneurysms of the anterior communicating artery treated at a neurosurgical service in Southern Brazil"],"prefix":"10.25259","volume":"10","author":[{"given":"Fabiano Pasqualotto","family":"Soares","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maira Cristina","family":"Velho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apio Claudio Martins","family":"Antunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,10,4]]},"reference":[{"key":"10.25259\/SNI_41_2019\/ref-1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1055\/s-2008-1073169","article-title":"Anterior communicating artery aneurysms: An overview","volume":"51","author":"Agrawal","year":"2008","journal-title":"Minim Invasive Neurosurg"},{"key":"10.25259\/SNI_41_2019\/ref-2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1055\/s-2008-1058367","article-title":"Anterior communicating artery aneurysm surgery through the orbitopterional approach: Long-term follow-up in a series of 75 consecutive patients","volume":"18","author":"Andaluz","year":"2008","journal-title":"Skull Base"},{"key":"10.25259\/SNI_41_2019\/ref-3","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1227\/NEU.0b013e318285c3db","article-title":"The relationship between delayed infarcts and angiographic vasospasm after aneurysmal subarachnoid hemorrhage","volume":"72","author":"Brown","year":"2013","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_41_2019\/ref-4","first-page":"22","article-title":"Considera\u00e7\u00f6es hemodin\u00e2micas sobre abordagem dos aneurismas da art\u00e9ria comunicante anterior [Haemodynamic considerations regarding the approach to anterior communicating artery aneurysms]","volume":"7","author":"Chemale","year":"1996","journal-title":"J Bras Neurocir"},{"key":"10.25259\/SNI_41_2019\/ref-5","first-page":"E1","article-title":"Natural history and general management of unruptured intracranial aneurysms","volume":"17","author":"Chen","year":"2004","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI_41_2019\/ref-6","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1161\/STR.0b013e3182587839","article-title":"Guidelines for the management of aneurysmal subarachnoid hemorrhage: A guideline for healthcare professionals from the American heart association\/ American stroke association","volume":"43","author":"Connolly","year":"2012","journal-title":"Stroke"},{"key":"10.25259\/SNI_41_2019\/ref-7","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/978-3-319-04981-6_39","article-title":"Prospective factors of temporary arterial occlusion during anterior communicating artery aneurysm repair","volume":"120","author":"de Ara\u00fajo J\u00fanior","year":"2015","journal-title":"Acta Neurochir Suppl"},{"key":"10.25259\/SNI_41_2019\/ref-8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1080\/01616412.1993.11740148","article-title":"Surgical approaches to the anterior communicating artery aneurysm and their results","volume":"15","author":"Diraz","year":"1993","journal-title":"Neurol Res"},{"key":"10.25259\/SNI_41_2019\/ref-9","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1161\/STROKEAHA.114.004519","article-title":"Multidisciplinary consensus on assessment of unruptured intracranial aneurysms: Proposal of an international research group","volume":"45","author":"Etminan","year":"2014","journal-title":"Stroke"},{"key":"10.25259\/SNI_41_2019\/ref-10","doi-asserted-by":"crossref","first-page":"F1000","DOI":"10.12688\/f1000research.6635.1","article-title":"Advances in the understanding of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage","volume":"4","author":"Flynn","year":"2015","journal-title":"F1000Res"},{"key":"10.25259\/SNI_41_2019\/ref-11","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.wneu.2013.02.068","article-title":"The impact of temporary artery occlusion during intracranial aneurysm surgery on long-term clinical outcome: Part I. 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