{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T20:54:18Z","timestamp":1774644858602,"version":"3.50.1"},"reference-count":15,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Sarcoidosis, a multisystem inflammatory non-caseating granulomatous disease, can present with neurologic lesions in up to 10% of patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 57-year-old male presented with three months of worsening upper extremity radicular pain associated with dysmetria, hyperreflexia, bilateral Hoffman\u2019s, and positive Babinski signs. The contrast magnetic resonance imaging (MRI) showed a diffuse T2 signal hyperintensity and T1-enhancing 2.5 cm lesion extending sagittally between C4 and C6. The cerebrospinal fluid analysis showed a high protein level and lymphocytic pleocytosis. A cardiac positron emission tomography scan was consistent with the diagnosis of cardiac sarcoidosis. With the diagnosis of multisystemic\/probable neurosarcoidosis, the patient was unsuccessfully treated with intravenous methylprednisolone, followed by infliximab. Due to severe cord compression\/myelopathy, a C3\u2013C6 laminectomy and C3\u2013C7 posterior spinal fusion were performed. Postoperatively, the patient developed a transient right-sided hemiparesis. Over nine postoperative months, the patient had four relapses of transient repeated episodes of paresis, although follow-up cervical MRI scans revealed adequate cord decompression with a stable intramedullary hyperintense lesion.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Patients with neurosarcoidosis respond unpredictably to surgical decompression and require prolonged medical care, which is often unsuccessful.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_41_2024","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T09:33:30Z","timestamp":1709890410000},"page":"76","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Surgical management of intramedullary cervical spinal sarcoidosis complicated by transient unilateral weakness: A case report"],"prefix":"10.25259","volume":"15","author":[{"given":"Aziz","family":"Saade","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, California, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayley M.","family":"Denwood","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Boston Medical Center, One Boston Medical Center Place, Boston, Massachusetts, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Tannoury","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Boston Medical Center, One Boston Medical Center Place, Boston, Massachusetts, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chadi","family":"Tannoury","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Boston Medical Center, One Boston 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