{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T23:30:19Z","timestamp":1750894219400},"reference-count":13,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nPatients with brain vascular disease and hydrocephalus may be predisposed to acute ischemic stroke in case of shunt dysfunction and subsequent increased intracranial pression. Patients with brain tumor may develop hydrocephalus as a consequence of obstruction of cerebrospinal fluid pathways and radiation-induced moyamoya syndrome secondary (RIMS) to radiotherapy (RT).<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA 15-year-old male patient, affected by hydrocephalus and RIMS, presented acute cerebral ischemia after an episode of shunt malfunction. The shunt was promptly revised and the areas of ischemia visible at magnetic resonance imaging significantly decreased.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nChildren who receive RT for brain tumor, particularly if the circle of Willis region is involved, require close surveillance for the development of vasculopathy and consequent stroke. This surveillance must be even tighter if the patient has been treated with ventricular shunt for the possible synergistic interaction between the two causes on reducing cerebral perfusion and increasing the risk of acute ischemic events.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_434_2022","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T10:38:34Z","timestamp":1657881514000},"page":"306","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute ischemic stroke secondary to ventriculoperitoneal shunt dysfunction in a child with Moyamoya syndrome"],"prefix":"10.25259","volume":"13","author":[{"given":"Francesca","family":"Vitulli","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Neurosurgery Unit, AORN Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy."},{"name":"Department of Neurosciences and Reproductive and Dental Sciences, Division of Neurosurgery, Federico II University of Naples, Naples, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Spennato","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Neurosurgery Unit, AORN Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Cicala","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Neuroradiology Unit, AORN Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Mirone","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Neurosurgery Unit, AORN Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Rosaria","family":"Scala","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Neurosurgery Unit, AORN Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy."},{"name":"Department of Neurosciences and Reproductive and Dental Sciences, Division of Neurosurgery, Federico II University of Naples, Naples, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Cinalli","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Neurosurgery Unit, AORN Santobono-Pausilipon Children\u2019s Hospital, Naples, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"10.25259\/SNI_434_2022\/ref-1","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1161\/STROKEAHA.112.661561","article-title":"Cranial irradiation increases risk of stroke in pediatric brain tumor survivors","volume":"43","author":"Campen","year":"2012","journal-title":"Stroke"},{"key":"10.25259\/SNI_434_2022\/ref-2","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.pediatrneurol.2011.02.007","article-title":"Childhood moyamoya disease and moyamoya syndrome: A pictorial review","volume":"44","author":"Currie","year":"2011","journal-title":"Pediatr Neurol"},{"key":"10.25259\/SNI_434_2022\/ref-3","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1016\/j.ijrobp.2006.01.038","article-title":"Radiation-induced moyamoya syndrome","volume":"65","author":"Desai","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.25259\/SNI_434_2022\/ref-4","doi-asserted-by":"crossref","first-page":"420","DOI":"10.3171\/2009.6.PEDS096","article-title":"Pressure autoregulation, intracranial pressure, and brain tissue oxygenation in children with severe traumatic brain injury","volume":"4","author":"Figaji","year":"2009","journal-title":"J Neurosurg Pediatr"},{"key":"10.25259\/SNI_434_2022\/ref-5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1667\/RADE-20-00147.1","article-title":"Brain damage and patterns of neurovascular disorder after ionizing irradiation. 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