{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T09:29:10Z","timestamp":1745486950858},"reference-count":73,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\"><jats:title>Background:<\/jats:title><jats:p>A spinal intramedullary abscess is a rare clinical entity in which patients classically present with a subacute myelopathy and progressive paraplegia, sensory deficits, and\/or bowel and bladder dysfunction. We report the second case of spinal intramedullary abscess caused by<jats:italic>Candida albicans<\/jats:italic>to ever be published and the first case of its kind to be surgically managed.<\/jats:p><\/jats:sec><jats:sec id=\"st2\"><jats:title>Case Description:<\/jats:title><jats:p>A 44-year-old female presented with severe lumbar pain associated with paraparesis, incontinence, and paraplegia. She reported multiple hospital admissions and had a history of seizures, having already undergone treatment for neurotuberculosis and fungal infection of the central nervous system unsuccessfully. Nevertheless, no laboratory evidence of immunosuppression was identified on further investigation. Magnetic resonance imaging showed a D10-D11, well-circumscribed, intramedullary mass within the conus, which was hypointense on T1-weighted imaging and hyperintense on T2\/STIR weighted. The patient underwent surgery for removal and biopsy of the lesion, which provided the diagnosis of an intramedullary abscess caused by<jats:italic>C. albicans<\/jats:italic>, a very rare condition with only one case reported in literature so far.<\/jats:p><\/jats:sec><jats:sec id=\"st3\"><jats:title>Conclusion:<\/jats:title><jats:p><jats:italic>C. albicans<\/jats:italic>intramedullary abscess is a very rare clinical entity, especially in immunocompetent patients. We highlight<jats:italic>C. albicans<\/jats:italic>as an important etiology that must be considered in differential diagnosis. Critical evaluation of every case, early diagnosis, timely referral and surgical management of the abscess is essential to improve neurological outcome.<\/jats:p><\/jats:sec>","DOI":"10.25259\/sni_435_2021","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T12:00:42Z","timestamp":1623672042000},"page":"275","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Spinal intramedullary abscess due to<i>Candida albicans<\/i>in an immunocompetent patient: A rare case report"],"prefix":"10.25259","volume":"12","author":[{"given":"Paulo Eduardo Albuquerque Zito","family":"Raffa","sequence":"first","affiliation":[{"name":"Department of Medicine, Catanduva Medical School (FAMECA-UNIFIPA), Catanduva, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael Caiado Caixeta","family":"Vencio","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pontifical Catholic University of Goi\u00e1s, Goi\u00e2nia, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre Costa Corral","family":"Ponce","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine of ABC, Santo Andr\u00e9, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Pricoli","family":"Malamud","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine of ABC, Santo Andr\u00e9, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabela Caiado","family":"Vencio","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine of Pontifical Catholic University of S\u00e3o Paulo, Sorocaba, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar Cozar","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Santa Paula Hospital, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe D\u2019Almeida","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Pathology, DASA, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Roberto","family":"Franceschini","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, University of Caxias do Sul, Caxias do Sul, Rio Grande do Sul, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger Thomaz Rotta","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Santa Paula Hospital, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Henrique Pires","family":"Aguiar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Neurology, Catholic Pontifical University of 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