{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T01:47:53Z","timestamp":1782524873285,"version":"3.54.5"},"reference-count":16,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background:<\/jats:title>\n<jats:p>Headaches are common in Chiari Type 1 malformation (CM-1). The prevalence of migraine headaches in CM-1 is similar to that of the general population. However, when migraine headaches occur with CM-1, they tend to have an earlier age of onset, are more frequent and certainly more severe than when they occur without CM-1 association. The exact role or impact of CM-1 in migraine headaches has not been fully elucidated.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description:<\/jats:title>\n<jats:p>We report a fatal case of status migrainosus in 7 years old with CM-1 and review the literature on the possible associations.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Migraines occurring in association with CM-1 pose a management challenge and can be potentially fatal especially if associated with autonomic symptoms. The exact pathophysiological interaction between these two conditions when they occur simultaneously needs to be further elucidated.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_491_2019","type":"journal-article","created":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T06:43:52Z","timestamp":1576219432000},"page":"243","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fatal status migrainosus in Chiari 1 malformation"],"prefix":"10.25259","volume":"10","author":[{"given":"Luxwell","family":"Jokonya","sequence":"first","affiliation":[{"name":"Department of Surgery, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney","family":"Makarawo","sequence":"additional","affiliation":[{"name":"Department of Surgery, Parirenyatwa Hospital, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariro Lavender","family":"Mduluza-Jokonya","sequence":"additional","affiliation":[{"name":"Department of Medical Lab-Sciences, University of KwaZulu Natal, South Africa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gift","family":"Ngwende","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Zimbabwe, Harare, Zimbabwe,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"10.25259\/SNI_491_2019\/ref-1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/bmj.1.5377.225","article-title":"Fatal infarction of the brain in migraine","volume":"1","author":"Guest","year":"1964","journal-title":"Br Med J"},{"key":"10.25259\/SNI_491_2019\/ref-2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s10194-018-0889-4","article-title":"Survival outcome and mortality rate in patients with migraine: A population-based cohort 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the jockey?","volume":"22","author":"Miglis","year":"2018","journal-title":"Curr Pain Headache Rep"},{"key":"10.25259\/SNI_491_2019\/ref-10","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1111\/1556-4029.12836","article-title":"Sudden cardiac death in a young man with migraine-associated arrhythmia","volume":"60","author":"Monroe","year":"2015","journal-title":"J Forensic Sci"},{"key":"10.25259\/SNI_491_2019\/ref-11","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1212\/WNL.42.8.1519","article-title":"Headache in Type I Chiari malformation","volume":"42","author":"Pascual","year":"1992","journal-title":"Neurology"},{"key":"10.25259\/SNI_491_2019\/ref-12","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s11916-002-0056-z","article-title":"Headache and Chiari I malformation: Clinical presentation, diagnosis, and controversies in management","volume":"6","author":"Taylor","year":"2002","journal-title":"Curr Pain Headache 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