{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T02:55:19Z","timestamp":1695005719407},"reference-count":5,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Osseous hyperpigmentation of the calvarium is an extremely rare finding with only few reported cases in literature.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>The case is of a 59-year-old Caucasian male who presented with an acute history of generalized tonic clonic seizures and progressive weakness of the right upper limb. He had a background history of a malignant melanoma which had been resected from his left external acoustic meatus 4 weeks prior. Neuroimaging of the brain showed an intra-axial space-occupying lesion in his left parietal lobe with no associated osseous changes. A left mini parietal craniotomy was performed which revealed black discoloration of the parietal bone. The lesion was successfully resected and the bone flap was secured back in place. The patient was discharged on the 4<jats:sup>th<\/jats:sup> day postoperatively with no complications. The unusual finding of black discoloration of the calvarium was found to be secondary to adolescent tetracycline use.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Calvarial hyperpigmentation is a phenomenon encountered incidentally and will often come as surprise for surgeons. Once encountered, thorough history taking and examination should be done to investigate the cause.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_493_2023","type":"journal-article","created":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T10:06:26Z","timestamp":1691748386000},"page":"289","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Calvarial hyperpigmentation"],"prefix":"10.25259","volume":"14","author":[{"given":"Devon","family":"van Eck","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blessing","family":"Ndlovu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Ouwais Abdul","family":"Sattar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denver","family":"Naicker","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morena Nthuse","family":"Mpanza","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Richard Bwire","family":"Ouma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Witwatersrand, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Profyris","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2023,8,11]]},"reference":[{"key":"10.25259\/SNI_493_2023\/ref-1","doi-asserted-by":"crossref","first-page":"e3061","DOI":"10.1097\/GOX.0000000000003061","article-title":"Etiology of craniofacial bone hyperpigmentation and an algorithm for addressing intraoperative discovery","volume":"8","author":"Chubb","year":"2020","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.25259\/SNI_493_2023\/ref-2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2165\/00002018-199818060-00004","article-title":"Minocycline-induced pigmentation. Incidence, prevention and management","volume":"18","author":"Eisen","year":"1998","journal-title":"Drug Saf"},{"key":"10.25259\/SNI_493_2023\/ref-3","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1017\/S002221511500016X","article-title":"Rusty green stained temporal bone associated with exposure to tetracycline: An unusual presentation of black bone disease","volume":"129","author":"Farahnik","year":"2015","journal-title":"J Laryngol Otol"},{"key":"10.25259\/SNI_493_2023\/ref-4","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1111\/j.1365-4632.2004.02108.x","article-title":"Tetracycline and other tetracycline-derivative staining of the teeth and oral cavity","volume":"43","author":"S\u00e1nchez","year":"2004","journal-title":"Int J Dermatol"},{"key":"10.25259\/SNI_493_2023\/ref-5","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S8756-3282(96)00302-X","article-title":"Minocycline prevents the decrease in bone mineral density and trabecular bone in ovariectomized aged rats","volume":"19","author":"Williams","year":"1996","journal-title":"Bone"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/calvarial-hyperpigmentation\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/calvarial-hyperpigmentation\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T10:06:30Z","timestamp":1691748390000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/calvarial-hyperpigmentation\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,11]]},"references-count":5,"alternative-id":["10.25259\/SNI_493_2023"],"URL":"https:\/\/doi.org\/10.25259\/sni_493_2023","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8,11]]},"article-number":"289"}}