{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:59:21Z","timestamp":1785488361181,"version":"3.56.0"},"reference-count":19,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Neurocysticercosis (NCC) is the most common parasitic infection of the central nervous system and a major cause of acquired epilepsy in endemic regions. Solitary parenchymal lesions frequently mimic tuberculoma or high-grade glioma, posing a significant diagnostic challenge, particularly in tuberculosis-endemic and resource-limited settings.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n We report the case of a 60-year-old male farmer with diabetes mellitus who presented with a 1-week history of focal seizures with secondary generalization and progressive left-sided weakness. Neurological examination revealed a Glasgow Coma Scale score of 15\/15 and grade 4+ power in the left upper and lower limbs, with no sensory deficit. The patient had a prior history of treated pulmonary tuberculosis. Brain magnetic resonance imaging demonstrated a solitary ring-enhancing lesion in the right medial frontal lobe, with differential diagnoses of tuberculoma versus high-grade glioma. He underwent right parietal craniotomy with a transcortical approach and gross total excision of a well-circumscribed lesion. Histopathological examination revealed a cysticercus larva with surrounding inflammatory infiltrate, confirming NCC. Postoperatively, the patient received albendazole (15 mg\/kg\/day) for 2 weeks and continued antiepileptic therapy. Follow-up imaging showed complete resolution of the lesion, and the patient remained seizure-free with full neurological recovery.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n NCC should be considered in the differential diagnosis of solitary ring-enhancing brain lesions even in patients with prior tuberculosis. When imaging is inconclusive, surgical excision provides definitive diagnosis and effective treatment with excellent neurological and seizure outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_494_2026","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:22:35Z","timestamp":1785486155000},"page":"440","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Solitary neurocysticercosis mimicking tuberculoma and glioblastoma: A diagnostic challenge in a low-resource setting"],"prefix":"10.25259","volume":"17","author":[{"given":"Mohamedelamin Eltrafi","family":"Yousif","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima Mahmoud Ali","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Husam Mohamedahmed Babiker","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"10.25259\/SNI_494_2026\/ref-1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1212\/CPJ.0b013e31828d9f17","article-title":"Neurocysticercosis: Five new things","volume":"3","author":"Carpio","year":"2013","journal-title":"Neurol Clin Pract"},{"key":"10.25259\/SNI_494_2026\/ref-2","first-page":"e200","article-title":"The treatment of neurocysticercosis: A systematic review","volume":"2","author":"Carpio","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"key":"10.25259\/SNI_494_2026\/ref-3","first-page":"1344","article-title":"Neurocysticercosis among patients with solitary cerebral cysticercus granuloma","volume":"53","author":"Del Brutto","year":"1999","journal-title":"Neurology"},{"key":"10.25259\/SNI_494_2026\/ref-4","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jns.2016.11.045","article-title":"Revised diagnostic criteria for neurocysticercosis","volume":"372","author":"Del Brutto","year":"2017","journal-title":"J Neurol Sci"},{"key":"10.25259\/SNI_494_2026\/ref-5","first-page":"539","article-title":"Neurocysticercosis: Pathology and immunology","volume":"38","author":"Fleury","year":"2016","journal-title":"Semin Immunopathol"},{"key":"10.25259\/SNI_494_2026\/ref-6","first-page":"131","article-title":"Neurocysticercosis: Current perspectives","volume":"15","author":"Fleury","year":"2022","journal-title":"Infect Drug Resist"},{"key":"10.25259\/SNI_494_2026\/ref-7","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1474-4422(05)70194-0","article-title":"Neurocysticercosis: Updated concepts about an old disease","volume":"4","author":"Garcia","year":"2005","journal-title":"Lancet Neurol"},{"key":"10.25259\/SNI_494_2026\/ref-8","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0140-6736(03)14117-7","article-title":"Taenia solium cysticercosis","volume":"362","author":"Garcia","year":"2003","journal-title":"Lancet"},{"key":"10.25259\/SNI_494_2026\/ref-9","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/S1474-4422(14)70094-8","article-title":"Clinical symptoms, diagnosis, and treatment of neurocysticercosis","volume":"13","author":"Garcia","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.25259\/SNI_494_2026\/ref-10","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nrneurol.2011.135","article-title":"Diagnosis and treatment of neurocysticercosis","volume":"7","author":"Nash","year":"2011","journal-title":"Nat Rev Neurol"},{"key":"10.25259\/SNI_494_2026\/ref-11","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3340\/jkns.2008.44.1.36","article-title":"Multiple tuberculoma involving the brain and spinal cord in a patient with miliary pulmonary tuberculosis","volume":"44","author":"Park","year":"2008","journal-title":"J Korean Neurosurg Soc"},{"key":"10.25259\/SNI_494_2026\/ref-12","first-page":"802","article-title":"Validation of diagnostic criteria for solitary cerebral cysticercus granuloma","volume":"86","author":"Rajshekhar","year":"1997","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_494_2026\/ref-13","doi-asserted-by":"crossref","first-page":"319","DOI":"10.4103\/0971-5916.198686","article-title":"Neurocysticercosis: Diagnostic problems and current therapeutic strategies","volume":"144","author":"Rajshekhar","year":"2016","journal-title":"Indian J Med Res"},{"key":"10.25259\/SNI_494_2026\/ref-14","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/epi.12159","article-title":"From seizures to epilepsy and its substrates: Neurocysticercosis","volume":"54","author":"Singh","year":"2013","journal-title":"Epilepsia"},{"key":"10.25259\/SNI_494_2026\/ref-15","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/978-3-319-50712-5_33","article-title":"Concurrent occurrence of brain tuberculoma along with spinal cord tuberculoma. 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