{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:39:37Z","timestamp":1790710777370,"version":"4.1.0"},"reference-count":30,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Background:<\/jats:title>Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a rare neuropathological entity, recently introduced in neuro-oncology. These tumors, histologically similar to oligodendrogliomas, cause epilepsy, occurring in children and young adults. Only few cases of PLNTY have been described in literature and all reported cases invariably focused on the onset of these tumors in children and young adults.<\/jats:p><\/jats:sec>Case Description:<\/jats:title>We report the case of a 50-year-old woman suffering from epilepsy since the 1st<\/jats:sup>year of her life. Computed tomography scan and magnetic resonance imaging of the brain documented the presence of a calcified mass involving left temporal lobe. The tumor was surgically excised and the histological examination showed a hypocellular and massively calcified neoplasm with morphological and immunohistochemical features consistent with the diagnosis of \u201cPLNTY.\u201d<\/jats:p><\/jats:sec>Conclusion:<\/jats:title>A review of the literature revealed that there are 31 cases of PLNTY reported in literature, most of which are children or young adults. The present case represents the second PLNTY diagnosed in a middle-aged adult to the best of our knowledge, suggesting that PLNTY should always be included in the differential diagnosis of low-grade brain tumors, also in adult patients.<\/jats:p><\/jats:sec>","DOI":"10.25259\/sni_500_2021","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T07:00:23Z","timestamp":1632121223000},"page":"470","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["A \u201cpolymorphous low-grade neuroepithelial tumor of the young (PLNTY)\u201d diagnosed in an adult. Report of a case and review of the literature"],"prefix":"10.25259","volume":"12","author":[{"given":"Giuseppe","family":"Broggi","sequence":"first","affiliation":[{"name":"Department of Medical, Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, Anatomic Pathology, University of Catania,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Certo","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, Neurological Surgery, Policlinico \u201cRodolico-San Marco\u201d University Hospital, University of Catania, 95123 Catania,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Altieri","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, Neurological Surgery, Policlinico \u201cRodolico-San Marco\u201d University Hospital, University of Catania, 95123 Catania,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Caltabiano","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical Sciences and Advanced Technologies \u201cG.F. Ingrassia\u201d, Anatomic Pathology, University of Catania,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Gessi","sequence":"additional","affiliation":[{"name":"Neuropathology Unit, Catholic University, Fondazione Policlinico Universitario \u201cA. Gemelli\u201d IRCSS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Maria Vincenzo","family":"Barbagallo","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical Sciences and Advanced Technologies \u201cG.F. 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