{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T05:13:10Z","timestamp":1732943590069,"version":"3.30.0"},"reference-count":13,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nGiant cell tumor of bone (GCTB) is a rare benign tumor that may also exhibit aggressive local behavior. Recurrence of GCTB is common even after complete resection. GCTB typically occurs in long bones, and only 2.7% are found in the spine. Here, a 28-year-old female with a magnetic resonance (MR)-documented L5 lumbar spine GCTB presented with a cauda equina syndrome effectively managed with a decompressive laminectomy\/L4\u2013S1 fusion.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA 28-year-old female presented with a 1-year history of lower extremity pain\/paresthesia that had exacerbated over the previous 1 month. When the MR imaging revealed cauda equina compression due to a L5 hypodense lesion, the patient successfully underwent a decompressive laminectomy\/L4\u2013S1 fusion. The histopathology examination confirmed the presence of a GCTB.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nWhile gross total excision for GCTB is the treatment of choice, for those undergoing only subtotal\/partial resections, additional adjuvant therapy may be warranted. Notably, even despite extensive resections, these lesions have a high rate of recurrence.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_533_2024","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T07:00:15Z","timestamp":1732863615000},"page":"436","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["L5 giant cell tumor in 28-year-old female"],"prefix":"10.25259","volume":"15","author":[{"given":"Wisnu","family":"Baskoro","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Dr. Soeradji Tirtonegoro Central Public Hospital, Klaten, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Fakhri Raiyan","family":"Pratama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Dr. Soeradji Tirtonegoro Central Public Hospital, Klaten, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Early Isnaeni Nur","family":"Fauziah","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Gadjah Mada University, Sleman, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanan Anwar","family":"Rusidi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Surakarta Central Public Hospital, Surakarta, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bidari","family":"Kameswari","sequence":"additional","affiliation":[{"name":"Department of Pathology Anatomy, Dr. Soeradji Tirtonegoro Central Public Hospital, Klaten, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"key":"10.25259\/SNI_533_2024\/ref-1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.25259\/SNI_207_2023","article-title":"Giant cell tumor of sacral vertebra in an adolescent without neurodeficit: A case report and review of the 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Giant cell tumor of the isehium A report of two cases and review of the literature","volume":"17","author":"Shankman","year":"1988","journal-title":"Skeletal Radiol"},{"key":"10.25259\/SNI_533_2024\/ref-12","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.spinee.2006.01.016","article-title":"Giant cell tumor of fifth lumbar vertebrae: Two case reports and review of the literature","volume":"7","author":"Shimada","year":"2007","journal-title":"Spine J"},{"key":"10.25259\/SNI_533_2024\/ref-13","first-page":"2","article-title":"Current concepts review: Giant cell tumor of bone-an overview","volume":"4","author":"Sobti","year":"2016","journal-title":"Arch Bone Jt Surg"}],"container-title":["Surgical Neurology 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