{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T01:42:03Z","timestamp":1788658923434,"version":"build-2803163510"},"reference-count":25,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background:<\/jats:title>\n<jats:p>Sellar arachnoid cysts (SACs) are rare lesions and incidentally found on brain imaging. The pathophysiology is poorly understood. Some authors suggested that SACs develop as a herniation of arachnoid membrane through the diaphragma sellae followed by cyst formation. Furthermore, Meyer <jats:italic>et al<\/jats:italic>. postulated that SACs are formed by splitting of the arachnoid layers. Symptomatic SACs present with headache, visual field deficit, or pituitary dysfunction. The data are limited on the indications and timing for intervention. We present a case of symptomatic SAC that was fenestrated using orbitofrontal approach.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description:<\/jats:title>\n<jats:p>A 64-year-old female presented with chronic headaches and blurriness of vision. She was previously diagnosed with diabetes insipidus (DI) that was treated with desmopressin, magnetic resonance imaging (MRI) of her brain at that time was normal. Later on, she developed severe headaches that were managed medically. A year later, she had an episode of generalized seizure that led to the discovery of SAC on brain MRI. On examination, she had a left-sided monocular temporal hemianopia. The patient underwent an orbitofrontal craniotomy for fenestration of the SAC. At 6-month follow-up, her headaches had significantly improved with the resolution of the visual deficit. In addition, the DI had resolved, and the desmopressin was discontinued.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>SACs are rare with no consensus on the indications for surgery. Our experience suggests that fenestration of SAC through transcranial approach is a valid option for patients with visual deficit and\/or pituitary dysfunction.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_541_2019","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T11:07:39Z","timestamp":1579259259000},"page":"10","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Orbitofrontal approach for the fenestration of a symptomatic sellar arachnoid cyst"],"prefix":"10.25259","volume":"11","author":[{"given":"Zaid","family":"Aljuboori","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery, University of Louisville, Louisville, Kentucky."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Burke","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, University of Louisville, Louisville, Kentucky."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heegok","family":"Yeo","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, University of Louisville, Louisville, Kentucky."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"McCallum","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, University of Louisville, Louisville, Kentucky."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Clark","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology, University of Louisville, Louisville, Kentucky."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Williams","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, University of Louisville, Louisville, Kentucky."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2020,1,17]]},"reference":[{"key":"10.25259\/SNI_541_2019\/ref-1","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3171\/2012.10.JNS12548","article-title":"Prevalence and natural history of arachnoid cysts in adults","volume":"118","author":"Al-Holou","year":"2013","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_541_2019\/ref-2","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3171\/jns.1984.60.1.0008","article-title":"Transsphenoidal treatment of non-neoplastic intrasellar cysts. 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