{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T23:50:33Z","timestamp":1776901833824,"version":"3.51.2"},"reference-count":33,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nMeningioma is the most common primary intracranial tumor. This single-center study aimed to analyze the clinicopathological, radiological profile, and outcomes of patients with intracranial meningiomas in terms of functional status, morbidity, mortality, and recurrence-free survival (RFS).<\/jats:p>\n<\/jats:sec>\n\nMethods: <\/jats:title>\nPatients of intracranial meningioma treated between January 01, 2010, and December 31, 2019, at the Department of Neurosurgery, King George\u2019s Medical University, India, were included in this study. Retrospective data analysis of 172 patients with intracranial meningioma was done.<\/jats:p>\n<\/jats:sec>\n\nResults: <\/jats:title>\nThe majority of the patients, that is, 94 (54.65%), presented in the 4th<\/jats:sup> and 5th<\/jats:sup> decade. The mean size of the meningioma was 36.4 \u00b1 4 mm (range: 26\u201368 mm). Of the 172 patients, 128 (74.41%) were diagnosed as non-skull base meningiomas, and in 44 patients (25.59%), meningioma originated from the skull base. Recurrence was observed on follow-up imaging in 11 patients after a mean postoperative interval of 55.2 \u00b1 5.8 months. Radiological meningioma recurrence paralleled with clinical deterioration in seven patients. Three of these patients were subjected to the second surgery, followed by radiotherapy, and in the remaining four patients, Gamma knife or fractionated radiotherapy was given.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nThe majority of patients had good functional outcomes (KPS >70) at discharge. Morbidity and mortality was 18.60% and 3.49%, respectively. Meningioma size \u22654 cm, age >45 years, World Health Organization Grade (II, III), non-skull base location, and Simpson grade III, IV of resection showed significantly shorter RFS.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_556_2024","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:33:18Z","timestamp":1734067998000},"page":"464","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Management of intracranial meningioma: Outcome analysis and clinico radiological profile of 172 patients"],"prefix":"10.25259","volume":"15","author":[{"given":"Aditya","family":"Varshney","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, SN Medical College, Agra, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somil","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankur","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Awdhesh","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chhitij","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bal Krishna","family":"Ojha","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shalini","family":"Bhalla","sequence":"additional","affiliation":[{"name":"Department of Pathology, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brijesh Pratap","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,12,13]]},"reference":[{"key":"10.25259\/SNI_556_2024\/ref-1","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1007\/s00701-015-2502-9","article-title":"Intracranial meningioma surgery in the elderly (over 65 years): Prognostic factors and outcome","volume":"157","author":"Chen","year":"2015","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_556_2024\/ref-2","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00701-019-03799-3","article-title":"Neurosurgical treatment and outcome patterns of meningioma in Sweden: A nationwide registry-based study","volume":"161","author":"Corell","year":"2019","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_556_2024\/ref-3","doi-asserted-by":"crossref","first-page":"e588","DOI":"10.1016\/j.wneu.2017.10.028","article-title":"The relevance of simpson grade resections in modern neurosurgical treatment of World Health Organization grade I, II, and III meningiomas","volume":"109","author":"Ehresman","year":"2018","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-4","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1590\/S0004-282X2007000400012","article-title":"Intracranial meningiomas: Magnetic resonance imaging findings in 78 cases","volume":"65","author":"Gasparetto","year":"2007","journal-title":"Arq Neuropsiquiatr"},{"key":"10.25259\/SNI_556_2024\/ref-5","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4103\/0028-3886.93589","article-title":"Does bony hyperostosis in intracranial meningioma signify tumor invasion? A radio-pathologic study","volume":"60","author":"Goyal","year":"2012","journal-title":"Neurol India"},{"key":"10.25259\/SNI_556_2024\/ref-6","doi-asserted-by":"crossref","first-page":"539","DOI":"10.18231\/j.ijpo.2019.105","article-title":"Clinicopathological study of meningioma from rural setup of central India : A 5 year experience","volume":"6","author":"Goyal","year":"2019","journal-title":"Indian J Pathol Oncol"},{"key":"10.25259\/SNI_556_2024\/ref-7","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/BF01403594","article-title":"Recurrences in meningioma after surgery","volume":"100","author":"Gupta","year":"1989","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_556_2024\/ref-8","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3171\/jns.1998.88.2.0304","article-title":"Platelet-activating factor and edema surrounding meningiomas","volume":"88","author":"Hirashima","year":"1998","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-9","doi-asserted-by":"crossref","first-page":"101562","DOI":"10.1016\/j.canep.2019.07.001","article-title":"Incidence, mortality and outcome of meningiomas: A population-based study from Germany","volume":"62","author":"Holleczek","year":"2019","journal-title":"Cancer Epidemiol"},{"key":"10.25259\/SNI_556_2024\/ref-10","first-page":"312","article-title":"Intracranial meningioma","volume":"8","author":"Howng","year":"1992","journal-title":"Gaoxiong Yi Xue Ke Xue Za Zhi"},{"key":"10.25259\/SNI_556_2024\/ref-11","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3171\/JNS-07\/08\/0325","article-title":"Gamma knife surgery for benign meningioma","volume":"107","author":"Kollova","year":"2007","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-12","doi-asserted-by":"crossref","first-page":"88","DOI":"10.21315\/mjms2018.25.3.9","article-title":"Incidence, clinico-radiological features and outcome of skull base versus non-skull base meningiomas treated in kuala lumpur general hospital: A five-year experience","volume":"25","author":"Kong","year":"2018","journal-title":"Malays J Med Sci"},{"key":"10.25259\/SNI_556_2024\/ref-13","first-page":"827","article-title":"Meningiomas: A clinicopathological study","volume":"4","author":"Lakshmi","year":"2015","journal-title":"Int J Med Res Health Sci"},{"key":"10.25259\/SNI_556_2024\/ref-14","doi-asserted-by":"crossref","first-page":"E4","DOI":"10.3171\/2018.1.FOCUS17752","article-title":"Relationship between tumor location, size, and WHO grade in meningioma","volume":"44","author":"Magill","year":"2018","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI_556_2024\/ref-15","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/BF01476410","article-title":"Intracranial meningiomas: Analysis of recurrence after surgical treatment","volume":"126","author":"Mahmood","year":"1994","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_556_2024\/ref-16","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3171\/jns.1999.91.3.0375","article-title":"Predicting the probability of meningioma recurrence based on the quantity of peritumoral brain edema on computerized tomography scanning","volume":"91","author":"Mantle","year":"1999","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.critrevonc.2008.01.010","article-title":"Meningioma","volume":"67","author":"Marosi","year":"2008","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.25259\/SNI_556_2024\/ref-18","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3340\/jkns.2012.52.1.14","article-title":"Intracranial meningiomas, WHO Grade Il : Prognostic implications of clinicopathologic features","volume":"52","author":"Moon","year":"2012","journal-title":"J Korean Neurosurg Soc"},{"key":"10.25259\/SNI_556_2024\/ref-19","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/ajns.AJNS_228_16","article-title":"Clinicopathological characteristics of meningiomas: Experience from a tertiary care hospital in the Kashmir Valley","volume":"14","author":"Mubeen","year":"2019","journal-title":"Asian J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-20","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3171\/jns.1999.90.3.0455","article-title":"Preoperative identification of meningiomas that are highly likely to recur","volume":"90","author":"Nakasu","year":"1999","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-21","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3171\/2016.1.JNS151842","article-title":"Relevance of Simpson grading system and recurrence-free survival after surgery for World Health Organization Grade I meningioma","volume":"126","author":"Nanda","year":"2017","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-22","doi-asserted-by":"crossref","first-page":"98","DOI":"10.2176\/nmc.oa.2020-0304","article-title":"Nation-wide brain tumor registry-based study of intracranial meningioma in Japan: Analysis of surgery-related risks","volume":"61","author":"Oya","year":"2021","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.25259\/SNI_556_2024\/ref-23","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1097\/00000478-199712000-00008","article-title":"Meningioma grading: An analysis of histologic parameters","volume":"21","author":"Perry","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"10.25259\/SNI_556_2024\/ref-24","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3171\/2014.7.JNS131644","article-title":"Meningiomas: Knowledge base, treatment outcomes, and uncertainties. A RANO review","volume":"122","author":"Rogers","year":"2015","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-25","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3171\/jns.1989.71.5.0665","article-title":"Incidence and clinicopathological features of meningioma","volume":"71","author":"Rohringer","year":"1989","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_556_2024\/ref-26","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejrad.2008.01.010","article-title":"Pathologic significance of the \u201cdural tail sign","volume":"70","author":"Rokni-Yazdi","year":"2009","journal-title":"\u201d Eur J Radiol"},{"key":"10.25259\/SNI_556_2024\/ref-27","doi-asserted-by":"crossref","first-page":"54","DOI":"10.14791\/btrt.2017.5.2.54","article-title":"Recurred intracranial meningioma: A retrospective analysis for treatment outcome and prognostic factor","volume":"5","author":"Ryu","year":"2017","journal-title":"Brain Tumor Res Treat"},{"key":"10.25259\/SNI_556_2024\/ref-28","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1590\/S0004-282X2002000500023","article-title":"Brain edema in meningiomas: Radiological and histological factors","volume":"60","author":"Souto","year":"2002","journal-title":"Arq Neuropsiquiatr"},{"key":"10.25259\/SNI_556_2024\/ref-29","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.3389\/fonc.2020.01412","article-title":"The preferred locations of meningioma according to different biological characteristics based on voxel-wise analysis","volume":"10","author":"Sun","year":"2020","journal-title":"Front Oncol"},{"key":"10.25259\/SNI_556_2024\/ref-30","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s11060-017-2481-1","article-title":"The Simpson grading in meningioma surgery: Does the tumor location influence the prognostic value?","volume":"133","author":"Vob","year":"2017","journal-title":"J Neurooncol"},{"key":"10.25259\/SNI_556_2024\/ref-31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11060-010-0386-3","article-title":"Epidemiology and etiology of meningioma","volume":"99","author":"Wiemels","year":"2010","journal-title":"J Neurooncol"},{"key":"10.25259\/SNI_556_2024\/ref-32","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ijge.2017.02.002","article-title":"Factors associated with recurrence of intracranial meningiomas after surgical resection: A retrospective single-center study","volume":"12","author":"Yang","year":"2018","journal-title":"Int J Gerontol"},{"key":"10.25259\/SNI_556_2024\/ref-33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000056986","article-title":"Meningioma: A cytogenetic model of a complex benign human tumor, including data on 394 karyotyped cases","volume":"93","author":"Zang","year":"2001","journal-title":"Cytogenet Cell Genet"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/management-of-intracranial-meningioma-outcome-analysis-and-clinico-radiological-profile-of-172-patients\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/management-of-intracranial-meningioma-outcome-analysis-and-clinico-radiological-profile-of-172-patients\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:33:44Z","timestamp":1734068024000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/management-of-intracranial-meningioma-outcome-analysis-and-clinico-radiological-profile-of-172-patients\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,13]]},"references-count":33,"alternative-id":["10.25259\/SNI_556_2024"],"URL":"https:\/\/doi.org\/10.25259\/sni_556_2024","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12,13]]},"article-number":"464"}}