{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T23:38:26Z","timestamp":1757547506334},"reference-count":53,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nSurgical resection for carotid body tumors (CBTs) is the gold standard of treatment and continues to be a challenging procedure, commonly associated with high vascular injury rates and neurological complications.<\/jats:p>\n<\/jats:sec>\n\nMethods: <\/jats:title>\nIt is a retrospective case series study between January 2002 and November 2020, with a mean follow-up of 29 months in a single nationwide referral center. Thirty-one patients diagnosed with a carotid body tumor and treated with microsurgical periadventitial resection were included in the study. Patients\u2019 demographics, comorbidities, clinical, radiological factors, and tumor grade, evaluated by the Shamblin scale, were obtained. Statistical analysis was performed on all collected data.<\/jats:p>\n<\/jats:sec>\n\nResults: <\/jats:title>\nIn this study, we included 31 patients (32 tumors), 80% of the patients were female, and 20% were male, with a mean age of 53 years. One patient presented with bilateral lesions, while 17 tumors were located on the left side. The most frequent symptom was a painless, slow-growing neck mass in 74% of patients. Using the Shamblin classification, 13% of tumors were Grade I, 53% Grade II, and 34% Grade III. In the postoperative period, 3% of patients presented with permanent cranial nerve deficit, while none had vascular injuries or postoperative stroke. A tumor >5 cm increased the risk for nerve lesion by 11 times (OR 12.6, CI 95% 7.4-11.4, P<\/jats:italic> < 0.001).<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nPreoperative embolization followed by periadventitial resection by means of a microsurgical technique is a safe and effective approach to remove CBT, with 3% cranial nerve injury rate and no need for vascular sacrifice or reconstruction.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_572_2022","type":"journal-article","created":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T08:44:17Z","timestamp":1666946657000},"page":"487","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Microsurgical treatment of carotid body tumors using periadventitial dissection: Analysis of outcomes and prognostic factors in a neurological referral center"],"prefix":"10.25259","volume":"13","author":[{"given":"Javier","family":"Degollado-Garc\u00eda","sequence":"first","affiliation":[{"name":"Department of Vascular Neurosurgery, Instuto Nacional de Neurolog\u00eda y Neurocirug\u00eda \u201cManuel Velasco Su\u00e1rez\u201d - Mexico City, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio","family":"Medina-Pizarro","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, United States,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Cano-Velazquez","sequence":"additional","affiliation":[{"name":"Department of Vascular Neurosurgery, Instuto Nacional de Neurolog\u00eda y Neurocirug\u00eda \u201cManuel Velasco Su\u00e1rez\u201d - Mexico City, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan C.","family":"Balc\u00e1zar-Padr\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Vascular Neurosurgery, Instuto Nacional de Neurolog\u00eda y Neurocirug\u00eda \u201cManuel Velasco Su\u00e1rez\u201d - Mexico City, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Gutierrez-Avila","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Hospital Civil de Guadalajara. Guadalajara City, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgar","family":"Nathal","sequence":"additional","affiliation":[{"name":"Department of Vascular Neurosurgery, Instuto Nacional de Neurolog\u00eda y Neurocirug\u00eda \u201cManuel Velasco Su\u00e1rez\u201d - Mexico City, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,10,28]]},"reference":[{"key":"10.25259\/SNI_572_2022\/ref-1","doi-asserted-by":"crossref","first-page":"E2386","DOI":"10.1002\/hed.24381","article-title":"Impact of preoperative embolization on the outcomes of carotid body tumor surgery: A meta-analysis and review of the literature","volume":"38","author":"Abu-Ghanem","year":"2016","journal-title":"Head Neck"},{"key":"10.25259\/SNI_572_2022\/ref-2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.amjsurg.2013.06.002","article-title":"Surgical resection of carotid body paragangliomas: 10 years of 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