{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:07:09Z","timestamp":1784887629601,"version":"3.55.0"},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Radiation-induced cavernous malformation within a vestibular schwannoma is rare, with only four previous cases reported.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n A 65-year-old female developed a radiation-induced cavernous malformation within a vestibular schwannoma 2 years after gamma knife radiosurgery, initially presenting with mild facial palsy. Six days later, she was admitted with an acute severe headache, trigeminal neuropathy, complete abducens palsy, complete facial palsy, and deafness. Computed tomography and magnetic resonance imaging revealed subarachnoid hemorrhage as well as an intratumoral hematoma. Three weeks after the hemorrhage, the tumor was gross totally removed to reduce the mass effect and prevent recurrent hemorrhage. However, her symptoms persisted after discharge.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n A review of reported cases suggests that radiation-induced cavernous malformation within vestibular schwannoma shows a higher rate of hemorrhagic transformation (80%) with multiple cranial nerve dysfunction compared with radiation-induced cavernous malformation in the brain (approximately 20%). Although radiation-induced cavernous malformation in vestibular schwannoma is rare, long-term follow-up is warranted.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_582_2026","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T09:42:23Z","timestamp":1784886143000},"page":"419","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiation-induced cavernous malformation arising within vestibular schwannoma manifesting as subarachnoid hemorrhage: Case report and literature review"],"prefix":"10.25259","volume":"17","author":[{"given":"Yoshinari","family":"Hirano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Numazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadayoshi","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"10.25259\/SNI_582_2026\/ref-1","doi-asserted-by":"crossref","first-page":"2050313X251390626","DOI":"10.1177\/2050313X251390626","article-title":"Radiation-induced cavernous malformation within a vestibular schwannoma: A case report","volume":"13","author":"Graboyes","year":"2025","journal-title":"SAGA Open Med Case Rep"},{"key":"10.25259\/SNI_582_2026\/ref-2","first-page":"1158","article-title":"Radiation-induced cavernomas of the brain","volume":"26","author":"Jain","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.25259\/SNI_582_2026\/ref-3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3171\/jns.1979.50.1.0081","article-title":"Combined neurilemmoma and angioma. Tumor of ectomesenchyme and a source of bleeding","volume":"50","author":"Kasantikul","year":"1979","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_582_2026\/ref-4","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s00701-011-0972-y","article-title":"Development of intratumoral cyst or extratumoral arachnoid cyst in intracranial schwannomas following gamma knife radiosurgery","volume":"153","author":"Murakami","year":"2011","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_582_2026\/ref-5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00701-018-3734-2","article-title":"De novo cavernous malformation arising in the wall of vestibular schwannoma following stereotactic radiosurgery: Case report and review of the literature","volume":"161","author":"Nussbaum","year":"2019","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_582_2026\/ref-6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s10143-021-01598-y","article-title":"Natural history and treatment options of radiation-induced brain cavernomas: A systematic review","volume":"45","author":"Patet","year":"2022","journal-title":"Neurosurg Rev"},{"key":"10.25259\/SNI_582_2026\/ref-7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.2176\/nmc.47.509","article-title":"Association of cavernous malformation within vestibular schwannoma: Immunohistochemical analysis of matrix metalloproteinase-2 and-9","volume":"47","author":"Sakata","year":"2007","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.25259\/SNI_582_2026\/ref-8","doi-asserted-by":"crossref","first-page":"E1006","DOI":"10.1227\/01.NEU.0000344005.23146.CC","article-title":"Gamma knife radiosurgery-induced cavernous hemangioma: Case report","volume":"64","author":"Sasagawa","year":"2009","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_582_2026\/ref-9","doi-asserted-by":"crossref","first-page":"105999","DOI":"10.1016\/j.bas.2026.105999","article-title":"Radiation-induced cavernous malformation in the brainstem after gamma knife radiosurgery for vestibular schwannoma: A case report and literature review","volume":"6","author":"Taule","year":"2026","journal-title":"Brain Spine"},{"key":"10.25259\/SNI_582_2026\/ref-10","first-page":"49","article-title":"Rapid tumor growth due to cavernous malformation-like lesion during long-term follow-up of gamma knife surgery for vestibular schwannoma","volume":"101E","author":"Watanabe","year":"2025","journal-title":"Chiba Med J"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/radiation-induced-cavernous-malformation-arising-within-vestibular-schwannoma-manifesting-as-subarachnoid-hemorrhage-case-report-and-literature-review\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/radiation-induced-cavernous-malformation-arising-within-vestibular-schwannoma-manifesting-as-subarachnoid-hemorrhage-case-report-and-literature-review\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T09:42:24Z","timestamp":1784886144000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/radiation-induced-cavernous-malformation-arising-within-vestibular-schwannoma-manifesting-as-subarachnoid-hemorrhage-case-report-and-literature-review\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,24]]},"references-count":10,"alternative-id":["10.25259\/SNI_582_2026"],"URL":"https:\/\/doi.org\/10.25259\/sni_582_2026","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,24]]},"article-number":"419"}}