{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T21:22:31Z","timestamp":1750540951006},"reference-count":6,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nKlippel-Feil syndrome (KFS) is defined by multiple abnormal segments of the cervical spine with congenital synostosis of two or more cervical vertebrae. KFS patients who demonstrate progressive symptomatic instability and\/or neurologic sequelae are traditionally managed with operative decompression and arthrodesis.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA 44-year-old female with chronic neck pain and radiculopathy and a C7-T1 KFS presented with adjacent segment degenerative disc disease at the C5-6 and C6-7 levels. She was successfully managed with a two-level cervical disc arthroplasty (CDA).<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nPatients with KFS and disease at two contiguous, adjacent levels (e.g., cervical disc disease) may be safely and effectively managed with two-level CDA.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_587_2020","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T06:50:25Z","timestamp":1601621425000},"page":"322","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Two-level cervical disc arthroplasty in patients with Klippel-Feil syndrome: A case report and review of the literature"],"prefix":"10.25259","volume":"11","author":[{"given":"Robert C.","family":"Ryu","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Cedars-Sinai Medical Center, Los Angeles, California, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip H.","family":"Behrens","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Cedars-Sinai Medical Center, Los Angeles, California, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blake A.","family":"Burkert","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Cedars-Sinai Medical Center, Los Angeles, California, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Patrick","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terrence T.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Cedars-Sinai Medical Center, Los Angeles, California, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2020,10,2]]},"reference":[{"key":"10.25259\/SNI_587_2020\/ref-1","first-page":"1","article-title":"Two-level cervical disc arthroplasty versus anterior cervical discectomy and fusion: 10-Year outcomes of a prospective, randomized investigational device exemption clinical trial","volume":"1","author":"Gornet","year":"2019","journal-title":"J Neurosurg Spine"},{"key":"10.25259\/SNI_587_2020\/ref-2","doi-asserted-by":"crossref","first-page":"190S","DOI":"10.1016\/j.spinee.2004.07.007","article-title":"Adjacent segment degeneration and adjacent segment disease: The consequences of spinal fusion?","volume":"4","author":"Hilibrand","year":"2004","journal-title":"Spine J"},{"key":"10.25259\/SNI_587_2020\/ref-3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ijsu.2016.09.088","article-title":"Cervical disc arthroplasty for symptomatic cervical disc disease: Traditional and Bayesian meta-analysis with trial sequential analysis","volume":"35","author":"Kan","year":"2016","journal-title":"Int J Surg"},{"key":"10.25259\/SNI_587_2020\/ref-4","doi-asserted-by":"crossref","first-page":"177S","DOI":"10.1016\/j.spinee.2004.07.003","article-title":"The indications for lumbar and cervical disc replacement","volume":"4","author":"McAfee","year":"2004","journal-title":"Spine J"},{"key":"10.25259\/SNI_587_2020\/ref-5","doi-asserted-by":"crossref","first-page":"e11755","DOI":"10.1097\/MD.0000000000011755","article-title":"Primary cervical disc arthroplasty versus cervical disc arthroplasty adjacent to previous fusion. A retrospective study with 48 months of follow-up","volume":"97","author":"Wu","year":"2018","journal-title":"Medicine (Baltimore)"},{"key":"10.25259\/SNI_587_2020\/ref-6","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00586-016-4655-5","article-title":"Anterior cervical discectomy and fusion (ACDF) versus cervical disc arthroplasty (CDA) for two contiguous levels cervical disc degenerative disease: A meta-analysis of randomized controlled trials","volume":"26","author":"Zou","year":"2017","journal-title":"Eur Spine J"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/two-level-cervical-disc-arthroplasty-in-patients-with-klippel-feil-syndrome-a-case-report-and-review-of-the-literature\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/two-level-cervical-disc-arthroplasty-in-patients-with-klippel-feil-syndrome-a-case-report-and-review-of-the-literature\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T06:50:32Z","timestamp":1601621432000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/two-level-cervical-disc-arthroplasty-in-patients-with-klippel-feil-syndrome-a-case-report-and-review-of-the-literature\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,2]]},"references-count":6,"alternative-id":["10.25259\/SNI_587_2020"],"URL":"https:\/\/doi.org\/10.25259\/sni_587_2020","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,2]]},"article-number":"322"}}