{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T13:13:51Z","timestamp":1661519631127},"reference-count":3,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Cerebral microhemorrhages are a complication in patients with severe COVID-19 pneumonia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 50-year-old woman presented to the hospital with shortness of breath due COVID-19 (SARS-CoV-2, alpha variant) pneumonia. Her hospital course was complicated by hypoxic respiratory failure requiring intubation and severe acute respiratory distress syndrome. She received a tracheostomy for ongoing ventilator support after prolonged intubation. Her mental status was notable for disorientation and severe agitation for which a magnetic resonance imaging (MRI) of the brain was obtained. MRI revealed numerous microhemorrhages predominantly at the gray-white matter junctions.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Cerebral microhemorrhages in severe COVID-19 pneumonia are associated with critical illness, increased mortality, and worse functional outcome. The pathophysiology of cerebral microhemorrhages in COVID-19 is unknown.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_605_2022","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T12:57:30Z","timestamp":1661518650000},"page":"380","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cerebral microhemorrhages in severe COVID-19 pneumonia"],"prefix":"10.25259","volume":"13","author":[{"given":"Melvin","family":"Parasram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamelia Y.","family":"Loiseau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"10.25259\/SNI_605_2022\/ref-1","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1161\/STROKEAHA.120.030940","article-title":"Cerebral microbleeds and leukoencephalopathy in critically Ill patients with COVID-19","volume":"51","author":"Agarwal","year":"2020","journal-title":"Stroke"},{"key":"10.25259\/SNI_605_2022\/ref-2","doi-asserted-by":"crossref","first-page":"E223","DOI":"10.1148\/radiol.2020202040","article-title":"COVID-19-associated diffuse leukoencephalopathy and microhemorrhages","volume":"297","author":"Radmanesh","year":"2020","journal-title":"Radiology"},{"key":"10.25259\/SNI_605_2022\/ref-3","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0140-6736(20)30937-5","article-title":"Endothelial cell infection and endotheliitis in COVID-19","volume":"395","author":"Varga","year":"2020","journal-title":"Lancet"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/cerebral-microhemorrhages-in-severe-covid-19-pneumonia\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/cerebral-microhemorrhages-in-severe-covid-19-pneumonia\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T12:57:32Z","timestamp":1661518652000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/cerebral-microhemorrhages-in-severe-covid-19-pneumonia\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,26]]},"references-count":3,"alternative-id":["10.25259\/SNI_605_2022"],"URL":"https:\/\/doi.org\/10.25259\/sni_605_2022","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,26]]},"article-number":"380"}}