{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T17:54:13Z","timestamp":1788285253409,"version":"build-2803163510"},"reference-count":30,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Brain abscesses are a potentially curable but life-threatening medical condition. Their occurrence within brain metastases has been exceptionally reported. In this study, we describe in detail this rare entity.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A previously healthy 64-year-old female was referred to our neurosurgical department with right-sided deviation of the oral commissure and a 7-day history of holocranial headache. Magnetic resonance imaging revealed a tumor in the right frontal lobe, exhibiting an iso-intense signal on T1-weighted images with heterogeneous enhancement. On diffusion-weighted imaging, the lesion displayed a hyperintense signal. A body computed tomography scan identified a lung tumor in the left superior lobe and a potential metastasis in the right adrenal gland. Intraoperative findings and histopathological examination revealed metastasis from lung adenocarcinoma. In addition, purulent content was noted within the abscess, and cultures identified <jats:italic>Staphylococcus epidermidis<\/jats:italic> and <jats:italic>Streptococcus mitis<\/jats:italic>.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Abscess formation within metastases is rarely diagnosed preoperatively, primarily because these lesions do not present with characteristic clinical or radiological features. Early recognition of this entity is crucial for establishing an appropriate treatment plan.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_62_2025","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T07:15:39Z","timestamp":1749798939000},"page":"236","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Abscess formation within brain metastasis"],"prefix":"10.25259","volume":"16","author":[{"given":"Emilio Gonz\u00e1lez","family":"Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo Daniel Mattos","family":"Piaggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2025,6,13]]},"reference":[{"key":"10.25259\/SNI_62_2025\/ref-1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1186\/s13256-024-04722-w","article-title":"Cerebellar abscess secondary to metastatic lung adenocarcinoma: A case report","volume":"18","author":"Ahmed","year":"2024","journal-title":"J Med Case Rep"},{"key":"10.25259\/SNI_62_2025\/ref-2","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1259\/bjr\/90100265","article-title":"Distinction between pyogenic brain abscess and necrotic brain tumour using 3-tesla MR spectroscopy, diffusion and perfusion imaging","volume":"82","author":"Chiang","year":"2009","journal-title":"Br J Radiol"},{"key":"10.25259\/SNI_62_2025\/ref-3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s11060-004-8093-6","article-title":"Brain metastases: Epidemiology and pathophysiology","volume":"75","author":"Gavrilovic","year":"2005","journal-title":"J Neurooncol"},{"key":"10.25259\/SNI_62_2025\/ref-4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ijscr.2015.03.012","article-title":"Abscess formation within a cerebellar metastasis: Case report and literature review","volume":"10","author":"Goto","year":"2015","journal-title":"Int J Surg Case Rep"},{"key":"10.25259\/SNI_62_2025\/ref-5","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1158\/1078-0432.CCR-08-2124","article-title":"The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain","volume":"15","author":"Grinberg-Rashi","year":"2009","journal-title":"Clin Cancer Res"},{"key":"10.25259\/SNI_62_2025\/ref-6","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jocn.2005.11.031","article-title":"Abscess formation within invasive pituitary adenoma","volume":"13","author":"Hatiboglu","year":"2006","journal-title":"J Clin Neurosci"},{"key":"10.25259\/SNI_62_2025\/ref-7","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S1607-551X(09)70182-2","article-title":"Differentiation among metastatic brain tumors, radiation necroses, and brain abscesses using proton magnetic resonance spectroscopy","volume":"20","author":"Hwang","year":"2004","journal-title":"Kaohsiung J Med Sci"},{"key":"10.25259\/SNI_62_2025\/ref-8","doi-asserted-by":"crossref","first-page":"829","DOI":"10.2176\/nmc.32.829","article-title":"Abscess within a glioblastoma multiforme--case report","volume":"32","author":"Ichikawa","year":"1992","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.25259\/SNI_62_2025\/ref-9","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000028997","article-title":"Rathke\u2019s cleft cyst abscess","volume":"33","author":"Israel","year":"2000","journal-title":"Pediatr Neurosurg"},{"key":"10.25259\/SNI_62_2025\/ref-10","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF02478909","article-title":"Primary CNS lymphoma associated with streptococcal abscess: An autopsy case","volume":"16","author":"Kano","year":"1999","journal-title":"Brain Tumor Pathol"},{"key":"10.25259\/SNI_62_2025\/ref-11","first-page":"60","article-title":"Abscess formation within cerebellar metastatic carcinoma--report of two cases and review of the literature","volume":"116","author":"Kovacic","year":"2004","journal-title":"Wien Klin Wochenschr"},{"key":"10.25259\/SNI_62_2025\/ref-12","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3171\/jns.2001.94.2.0335","article-title":"Secondary abscess formation in pituitary adenoma after tooth extraction. 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