{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:45:49Z","timestamp":1784673949667,"version":"3.55.0"},"reference-count":9,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Myeloid sarcoma (MS), a rare extramedullary tumor composed of myeloid blast cells, is classified by the World Health Organization as a subtype of acute myeloid leukemia (AML). Isolated, primary, or nonleukemic MS has an incidence of 2\/1,000,000 adults and constitutes only 0.7% of all AML cases. MS presentations vary widely, with spinal involvement being rare.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A-year-old male presented with interscapular pain radiating to the right upper arm\/neck but was neurologically intact. Once diagnosed with isolated spinal MS, he underwent a surgical decompression followed by local irradiation, systemic chemotherapy, and bone marrow transplantation. Eight months postoperatively, however, he experienced a graft-versus-host rejection and required additional therapies.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Establishing the diagnosis of MS is challenging and typically requires histological confirmation (i.e., the presence of myeloblasts and granulocytic cells). However, optimal treatment strategies remain elusive; despite radiation, chemotherapy, bone marrow transplant\/other local therapies, the overall long-term prognosis for MS remains poor.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_640_2024","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T14:44:09Z","timestamp":1731681849000},"page":"415","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A rare case of spinal myeloid sarcoma"],"prefix":"10.25259","volume":"15","author":[{"given":"Wouter","family":"Deconinck","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Jessa Hospital, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Bamps","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Faculty of Medicine, University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Steelandt","sequence":"additional","affiliation":[{"name":"Department of Pathology, Jessa Hospital, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"Wissels","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Plazier","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Faculty of Medicine, University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Put","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salah-Eddine","family":"Achahbar","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Vanvolsem","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacha","family":"Meeuws","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Klein","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert","family":"Roosen","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Centre (LCRC), University of Hasselt, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"key":"10.25259\/SNI_640_2024\/ref-1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1186\/s12891-021-04066-2","article-title":"Diagnosis and surgical treatment of primary isolated aggressive lumbar myeloid sarcoma: A rare case report and review of the literatures","volume":"22","author":"Bai","year":"2021","journal-title":"BMC Musculoskelet Disord"},{"key":"10.25259\/SNI_640_2024\/ref-2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.21037\/acr-20-110","article-title":"Isolated myeloid sarcoma of lumbar spine without bone marrow involvement: A rare case report and treatment dilemma","volume":"5","author":"Bhandohal","year":"2021","journal-title":"AME Case Rep"},{"key":"10.25259\/SNI_640_2024\/ref-3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.5005\/jp-journals-10070-7041","article-title":"Myeloid sarcoma presenting with quadriparesis: A difficult journey through COVID times-lessons learned","volume":"8","author":"Chakraborty","year":"2021","journal-title":"Bengal Phys J"},{"key":"10.25259\/SNI_640_2024\/ref-4","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2169\/internalmedicine.9580-22","article-title":"Epidural spinal cord compression as the presenting manifestation of acute myeloid leukemia: A case report and literature review","volume":"62","author":"Fujikawa","year":"2023","journal-title":"Intern Med"},{"key":"10.25259\/SNI_640_2024\/ref-5","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1080\/10790268.2020.1771506","article-title":"Granulocytic sarcoma causing long spinal cord compression: Case report and literature review","volume":"45","author":"Han","year":"2022","journal-title":"J Spinal Cord Med"},{"key":"10.25259\/SNI_640_2024\/ref-6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.25259\/SNI_1167_2022","article-title":"Myeloid sarcoma of the thoracic spine: A case report","volume":"14","author":"Patel","year":"2023","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_640_2024\/ref-7","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1055\/s-0041-1742079","article-title":"Spine myeloid sarcoma: A case series with review of the literature","volume":"10","author":"Shah","year":"2021","journal-title":"South Asian J Cancer"},{"key":"10.25259\/SNI_640_2024\/ref-8","doi-asserted-by":"crossref","first-page":"118","DOI":"10.29271\/jcpsp.2024.01.118","article-title":"Spinal myeloid sarcoma in a nonleukaemic patient","volume":"34","author":"Siddiqui","year":"2024","journal-title":"J Co ll Physicians Surg Pak"},{"key":"10.25259\/SNI_640_2024\/ref-9","doi-asserted-by":"crossref","first-page":"3825","DOI":"10.3892\/ol.2017.6620","article-title":"Clinicoradiological characteristics, management and prognosis of primary myeloid sarcoma of the central nervous system: A report of four cases","volume":"14","author":"Yang","year":"2017","journal-title":"Oncol Lett"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/a-rare-case-of-spinal-myeloid-sarcoma\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/a-rare-case-of-spinal-myeloid-sarcoma\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T14:44:12Z","timestamp":1731681852000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/a-rare-case-of-spinal-myeloid-sarcoma\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,15]]},"references-count":9,"alternative-id":["10.25259\/SNI_640_2024"],"URL":"https:\/\/doi.org\/10.25259\/sni_640_2024","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,15]]},"article-number":"415"}}