{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T15:28:50Z","timestamp":1774452530340,"version":"3.50.1"},"reference-count":32,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Decompressive hemicraniectomy (DH) has been performed for some cases of acute ischemic stroke in patients with coronavirus disease 2019 (COVID-19) infection, but there is little information about the clinical course and outcomes of these patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>We report a case of a 36-year-old woman with COVID-19 infection who developed stroke like symptoms while under home quarantine. Cranial CT scan showed an acute left internal carotid artery (ICA) infarct. She subsequently underwent an emergent left DH. Despite timely surgical intervention, she succumbed to chronic respiratory failure. A systematic review of SCOPUS and PubMed databases for case reports and case series of patients with COVID-19 infection who similarly underwent a DH for an acute ischemic infarct was performed. There were eight other reported cases in the literature. The patients\u2019 age ranged from 33 to 70 years (mean 48), with a female predilection (2:1). Respiratory preceded neurologic symptoms in 83% of cases. The ICA was the one most commonly involved in the stroke, and the mean NIHSS score was 20. DH was performed at a mean of 1.8 days post-ictus. Only four out of the nine patients were reported alive at the time of writing. The most common cause of death was respiratory failure (60%).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Clinicians have to be cognizant of the neurovascular complications that may occur during the course of a patient with COVID-19. DH for acute ischemic stroke associated with the said infection was reported in nine patients, but the outcomes were generally poor despite early surgical intervention.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_64_2021","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T06:17:16Z","timestamp":1616566636000},"page":"116","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Decompressive hemicraniectomy for acute ischemic stroke associated with coronavirus disease 2019 infection: Case report and systematic review"],"prefix":"10.25259","volume":"12","author":[{"given":"Kevin Ivan Pe\u00f1averde","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaric Emmanuel Mendoza","family":"Salonga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen Joy Ong","family":"Khu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"10.25259\/SNI_64_2021\/ref-1","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1136\/jnnp-2020-323522","article-title":"Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke","volume":"91","author":"Al Saiegh","year":"2020","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.25259\/SNI_64_2021\/ref-2","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1007\/s00134-020-06022-5","article-title":"Surviving sepsis campaign: Guidelines on the management of critically ill adults with Coronavirus disease 2019 (COVID-19)","volume":"46","author":"Alhazzani","year":"2020","journal-title":"Intensive Care Med"},{"key":"10.25259\/SNI_64_2021\/ref-3","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1161\/STROKEAHA.116.014727","article-title":"Timing of decompressive hemicraniectomy for stroke: A nationwide inpatient sample analysis","volume":"48","author":"Dasenbrock","year":"2017","journal-title":"Stroke"},{"key":"10.25259\/SNI_64_2021\/ref-4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/02688697.2020.1769553","article-title":"Licking the lungs, biting the brain: Malignant MCA infarct in a patient with COVID 19 infection","author":"De","year":"2020","journal-title":"Br J Neurosurg"},{"key":"10.25259\/SNI_64_2021\/ref-5","doi-asserted-by":"crossref","first-page":"e00028","DOI":"10.1128\/CMR.00028-20","article-title":"Coronavirus disease 2019-COVID-19","volume":"33","author":"Dhama","year":"2020","journal-title":"Clin Microbiol Rev"},{"key":"10.25259\/SNI_64_2021\/ref-6","doi-asserted-by":"crossref","first-page":"339","DOI":"10.5455\/medarh.2016.70.339-341","article-title":"Brain edema after ischaemic stroke","volume":"70","author":"Dostovic","year":"2016","journal-title":"Med Arch"},{"key":"10.25259\/SNI_64_2021\/ref-7","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1468-1331.2008.02063.x","article-title":"Differential diagnosis of cerebral infarction using an algorithm combining atrial fibrillation and D-dimer level","volume":"15","author":"Dougu","year":"2008","journal-title":"Eur J Neurol"},{"key":"10.25259\/SNI_64_2021\/ref-8","first-page":"423","article-title":"Decompressive craniotomy after middle cerebral artery infarction. 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