{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:34:45Z","timestamp":1712968485304},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Leiomyosarcoma (LMS) is a rare malignancy that originates from smooth muscle. The most common sites of metastases include the lungs, liver, kidney, and skin. Notably, metastases of LMS to the central nervous system\/or spine are extremely rare. When a cervical spinal LMS lesion was encountered, the patient successfully underwent gross total tumor resection with negative margins.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 63-year-old female had undergone an anterior cervical C5\u2013C7 diskectomy and fusion 18 years ago and resection of a retroperitoneal LMS 3 years ago. She newly presented with right-sided numbness and pain of 2 months duration that correlated with a focal right-sided C5-level hemiparesis (i.e., 4\/5 motor strength). When the cervical magnetic resonance demonstrated a right-sided C5 intralaminar mass with extension into the C5\u2013C6 foramen, she underwent posterior tumor resection; pathologically, this proved to be an LMS metastasis. Respectively, 1- and six months postoperatively, follow-up magnetic resonance imaging scans showed no tumor recurrence; she tolerated adjuvant oncological treatment accompanied by physical therapy. However, in one postoperative year, the lesion recurred, and she is presently under consideration for additional surgical management.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Gross total surgical resection is the first line of treatment for patients with metastatic LMS. Here, a patient with a C5 laminar\/C5\u2013C6 foraminal bony LMS metastasis underwent posterior tumor resection accompanied by adjuvant oncological treatment but exhibited disease recurrence within one postoperative year.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_66_2024","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T09:26:04Z","timestamp":1712913964000},"page":"128","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare presentation of leiomyosarcoma metastasis to the cervical spine: A case report and a brief review"],"prefix":"10.25259","volume":"15","author":[{"given":"Nenad","family":"Koruga","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Center Osijek, Osijek, Croatia"},{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alen","family":"Ron\u010devi\u0107","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anamarija Soldo","family":"Koruga","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"},{"name":"Department of Neurology, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmina","family":"Rajc","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"},{"name":"Department of Pathology and Forensic Medicine, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josipa","family":"Flam","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"},{"name":"Department of Oncology, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatjana","family":"Rotim","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"},{"name":"Department of Diagnostic and Interventional Radiology, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tajana","family":"Turk","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"},{"name":"Department of Diagnostic and Interventional Radiology, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"\u0160kilji\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia"},{"name":"Department of Anesthesiology and Critical Care, University Hospital Center Osijek, Osijek, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marijan","family":"Cesarik","sequence":"additional","affiliation":[{"name":"Department of Neurology, Po\u017eega County Hospital, Po\u017eega, Po\u017ee\u0161ko-Slavonska, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomislav","family":"Paun","sequence":"additional","affiliation":[{"name":"Department of Neurology, Po\u017eega County Hospital, Po\u017eega, Po\u017ee\u0161ko-Slavonska, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"10.25259\/SNI_66_2024\/ref-1","doi-asserted-by":"crossref","first-page":"e20294","DOI":"10.1371\/journal.pone.0020294","article-title":"Incidence of sarcoma histotypes and molecular subtypes in a prospective epidemiological study with central pathology review and molecular testing","volume":"6","author":"Ducimeti\u00e8re","year":"2011","journal-title":"PLoS One"},{"key":"10.25259\/SNI_66_2024\/ref-2","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3171\/spi.2007.6.2.178","article-title":"Leiomyosarcoma metastases to the 207spine. 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