{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T15:06:14Z","timestamp":1774019174412,"version":"3.50.1"},"reference-count":16,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Pleural mesothelioma (PM) is a tumor of the pleural epithelium with a poor prognosis. Asbestos exposure is closely related to its occurrence. To date, there have been 13 reports of PM with intradural invasion.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n A 73-year-old male was admitted with rapid progression of back pain and paraparesis. At age 67, he was diagnosed with PM (epithelial type) and underwent chemotherapy and a left thoracotomy for tumor resection. At present, the magnetic resonance newly showed T7-T9 spinal cord compressed due to an intradural tumor. Originating from the left pleura and invading the spinal canal through the intervertebral foramina, the lesion was subtotally resected. Histology confirmed that the intradural tumor lesion was a PM (biphasic type) that had transformed into a malignant tumor. Postoperatively, the patient\u2019s paraparesis improved. Despite the administration of adjuvant chemotherapy, the tumor showed regrowth 5 months later; further treatment was purely palliative care.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n In general, patients with PM have a poor prognosis. However, those with some favorable factors (i.e., epithelioid subtype, female sex, and early clinical stage) may survive for up to 5-years.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_68_2026","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T13:33:13Z","timestamp":1774013593000},"page":"155","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A case of delayed recurrence of pleural mesothelioma with intradural invasion"],"prefix":"10.25259","volume":"17","author":[{"given":"Hidetoshi","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Omichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuto","family":"Nigami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Shimokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,3,20]]},"reference":[{"key":"10.25259\/SNI_68_2026\/ref-1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s11060-009-9995-0","article-title":"Intradural intramedullary spinal cord metastasis due to mesothelioma","volume":"97","author":"Chamberlain","year":"2010","journal-title":"J Neurooncol"},{"key":"10.25259\/SNI_68_2026\/ref-2","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1136\/pgmj.50.589.718","article-title":"Malignant mesothelioma invading the spinal canal","volume":"50","author":"Cooper","year":"1974","journal-title":"Postgrad Med J"},{"key":"10.25259\/SNI_68_2026\/ref-3","first-page":"100557","article-title":"Extrathoracic metastases in pleural mesothelioma","volume":"4","author":"Dagogo-Jack","year":"2023","journal-title":"JTO Clin Res Rep"},{"key":"10.25259\/SNI_68_2026\/ref-4","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.neurol.2010.07.028","article-title":"[Solitary intramedullary metastasis from malignant pleural mesothelioma treated with CyberKnife\u00ae A case report]","volume":"167","author":"Dewas","year":"2011","journal-title":"Rev Neurol"},{"key":"10.25259\/SNI_68_2026\/ref-5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s11060-006-9215-0","article-title":"Perineural spread of malignant mesothelioma resulting in an intradural spinal cord mass: Case report","volume":"81","author":"Hillard","year":"2007","journal-title":"J Neurooncol"},{"key":"10.25259\/SNI_68_2026\/ref-6","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/ajns.AJNS_234_18","article-title":"Intramedullary metastasis to the cervical spinal cord from malignant pleural mesothelioma: Review of the literature and case reports","volume":"15","author":"Kalfas","year":"2020","journal-title":"Asian J Neurosurg"},{"key":"10.25259\/SNI_68_2026\/ref-7","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1445-5994.2005.00784.x","article-title":"Pleural mesothelioma with extension into the thoracic spinal cord","volume":"35","author":"Lee","year":"2005","journal-title":"Int Med J"},{"key":"10.25259\/SNI_68_2026\/ref-8","first-page":"e92","article-title":"Spinal cord compression: An unusual presentation of malignant pleural mesothelioma. 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Case report","volume":"49","author":"kura","year":"2009","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.25259\/SNI_68_2026\/ref-10","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00701-007-1255-5","article-title":"Intradural pleural malignant mesothelioma","volume":"149","author":"Payer","year":"2007","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_68_2026\/ref-11","doi-asserted-by":"crossref","first-page":"e552","DOI":"10.1016\/j.cllc.2020.09.019","article-title":"Brown-s\u00e9quard syndrome in a desmoplastic malignant mesothelioma patient: A rare complication","volume":"22","author":"Ralki","year":"2021","journal-title":"Clin Lung Cancer"},{"key":"10.25259\/SNI_68_2026\/ref-12","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1055\/s-0032-1309065","article-title":"Intradural perineural spread of mesothelioma causing myelopathy by tethering of the spinal cord","volume":"73","author":"Richter","year":"2012","journal-title":"J Neurol Surg Part A Cent Eur Neurosurg"},{"key":"10.25259\/SNI_68_2026\/ref-13","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3171\/jns.1998.88.1.0122","article-title":"Intradural neurotropic spread of malignant mesothelioma. 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