{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T19:12:19Z","timestamp":1761419539587},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>This report describes a case of an immunocompetent patient with an intradural abscess from <jats:italic>Candida dubliniensis<\/jats:italic>. The majority of fungal spine infections, although rare in general, are due to <jats:italic>Aspergillus<\/jats:italic> or <jats:italic>C. albicans<\/jats:italic> through systemic fungemia. To date, there have only been two reports of spondylodiscitis from <jats:italic>C. dubliniensis<\/jats:italic>.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 37-year-old immunocompetent female patient presented to the neurosurgical service for worsening headaches with nausea, vomiting, vision changes, and weight loss. MRI studies showed diffuse leptomeningeal enhancement of the distal spinal cord, conus medullaris, and nerve roots of the cauda equina extending beyond the neural foramina bilaterally. She had persistent symptoms and no clear diagnosis on lumbar puncture or systemic testing therefore L5-S1 laminectomy for an intradural tissue biopsy was performed. During surgery, cultures were taken and grew colonies of <jats:italic>C. dubliniensis<\/jats:italic>.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>This organism has been reported rarely in the literature as being an infectious agent, thus diagnosing remains a challenge but should be considered in patients with a suggestive history.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_750_2022","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T08:59:06Z","timestamp":1663923546000},"page":"435","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Lumbar cistern <i>Candida<\/i> intradural abscess following epidural anesthesia"],"prefix":"10.25259","volume":"13","author":[{"given":"Gabrielle","family":"Santangelo","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Rochester, Strong Memorial Hospital, Rochester, New York, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Stone","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Rochester, Strong Memorial Hospital, Rochester, New York, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahlon","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Neuropathology, University of Rochester, Strong Memorial Hospital, Rochester, New York, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Walter","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Rochester, Strong Memorial Hospital, Rochester, New York, United States."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,9,23]]},"reference":[{"key":"10.25259\/SNI_750_2022\/ref-1","first-page":"18","article-title":"Pyogenic intradural abscess of lumbar spine : A case report","volume":"11","author":"Cheon","year":"2015"},{"key":"10.25259\/SNI_750_2022\/ref-2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jinf.2004.08.020","article-title":"Candida spondylodiscitis and epidural abscess: Management with shorter courses of anti-fungal therapy in combination with surgical debridement","volume":"51","author":"Chia","year":"2005","journal-title":"J Infect"},{"key":"10.25259\/SNI_750_2022\/ref-3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/microbiolspec.EI10-0005-2015","article-title":"Fungal infections associated with contaminated steroid injections","volume":"4","author":"Kauffman","year":"2016","journal-title":"Microbiol Spectr"},{"key":"10.25259\/SNI_750_2022\/ref-4","doi-asserted-by":"crossref","first-page":"E354","DOI":"10.1097\/BRS.0b013e31805c0ab7","article-title":"Pyogenic intradural abcess: A case report","volume":"32","author":"Kulkarni","year":"2008","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.25259\/SNI_750_2022\/ref-5","doi-asserted-by":"crossref","first-page":"20140011","DOI":"10.1259\/bjr.20140011","article-title":"Pyogenic and non-pyogenic spinal infections: Emphasis on diffusion-weighted imaging for the detection of abscesses and pus collections","volume":"87","author":"Moritani","year":"2014","journal-title":"Br J Radiol"},{"key":"10.25259\/SNI_750_2022\/ref-6","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mmcr.2013.11.001","article-title":"Candida dubliniensis spondylodiscitis in an immunocompetent patient. Case report and review of the literature","volume":"3","author":"Oksi","year":"2014","journal-title":"Med Mycol Case Rep"},{"key":"10.25259\/SNI_750_2022\/ref-7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1136\/ard.47.6.522","article-title":"Intervertebral infection due to Candida albicans in an intravenous heroin abuser","volume":"47","author":"Rowe","year":"1988","journal-title":"Ann Rheum Dis"},{"key":"10.25259\/SNI_750_2022\/ref-8","first-page":"642","article-title":"Thoracic intradural Aspergillus abscess formation following epidural steroid injection","volume":"25","author":"Saigal","year":"2004","journal-title":"Am J Neuroradiol"},{"key":"10.25259\/SNI_750_2022\/ref-9","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.mmcr.2015.02.001","article-title":"Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient","volume":"8","author":"Salzer","year":"2015","journal-title":"Med Mycol Case Rep"},{"key":"10.25259\/SNI_750_2022\/ref-10","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1086\/522182","article-title":"Immune reconstitution syndrome and exacerbation of infections after pregnancy","volume":"45","author":"Singh","year":"2007","journal-title":"Clin Infect Dis"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/lumbar-cistern-candida-intradural-abscess-following-epidural-anesthesia\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/lumbar-cistern-candida-intradural-abscess-following-epidural-anesthesia\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T08:59:18Z","timestamp":1663923558000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/lumbar-cistern-candida-intradural-abscess-following-epidural-anesthesia\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,23]]},"references-count":10,"alternative-id":["10.25259\/SNI_750_2022"],"URL":"https:\/\/doi.org\/10.25259\/sni_750_2022","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,23]]},"article-number":"435"}}