{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:30:41Z","timestamp":1767349841495,"version":"3.48.0"},"reference-count":16,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Brain metastases from follicular thyroid carcinoma (FTC) are exceptionally rare, especially in the infratentorial region. Even rarer is when such a lesion precedes the diagnosis of the primary tumor. This case highlights the importance of maintaining diagnostic vigilance for metastatic disease, even in patients with seemingly benign thyroid pathology.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n A 55-year-old female presented with progressive imbalance and headache. Magnetic resonance imaging revealed a solid-cystic lesion in the cerebellar vermis compressing the fourth ventricle. She had a prior diagnosis of colloid goiter based on fine-needle aspiration cytology (FNAC). Intraoperatively, the lesion mimicked a hemangioblastoma; frozen section supported this diagnosis. However, final histopathology and immunohistochemistry confirmed metastatic FTC. Subsequent positron emission tomography-computed tomography and repeat thyroid FNAC confirmed the primary tumor, leading to total thyroidectomy and radioactive iodine therapy.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This case is likely the first reported instance of isolated cerebellar metastasis from FTC, masquerading as a primary central nervous system tumor. Surgeons should maintain a high index of suspicion when encountering posterior fossa tumors with atypical features, even with a prior benign thyroid FNAC.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_757_2025","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:27:50Z","timestamp":1767349670000},"page":"7","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolated cerebellar metastasis as the initial presentation of follicular thyroid carcinoma: A rare neurosurgical encounter"],"prefix":"10.25259","volume":"17","author":[{"given":"Preeti","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harsh Rajeshbhai","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhaya","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"10.25259\/SNI_757_2025\/ref-1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/dc.10043","article-title":"Fine-needle aspiration cytology of thyroid nodules: An institutional experience","volume":"26","author":"Baloch","year":"2002","journal-title":"Diagn Cytopathol"},{"key":"10.25259\/SNI_757_2025\/ref-2","doi-asserted-by":"crossref","first-page":"234","DOI":"10.4158\/EP.10.3.234","article-title":"Fine-needle aspiration of thyroid nodules: Past, present, and future","volume":"10","author":"Baloch","year":"2004","journal-title":"Endocr Pract"},{"key":"10.25259\/SNI_757_2025\/ref-3","first-page":"435","article-title":"Indications for therapy of metastatic thyroid carcinoma","volume":"95","author":"Bernet","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.25259\/SNI_757_2025\/ref-4","first-page":"149","article-title":"Brain metastases in patients with thyroid cancer","volume":"100","author":"D\u2019Avanzo","year":"2004","journal-title":"Cancer"},{"key":"10.25259\/SNI_757_2025\/ref-5","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.4103\/jcrt.jcrt_2017_21","article-title":"Dural and calvarial metastasis of thyroid follicular carcinoma mimicking Sindou type 6 parafalcine meningioma","volume":"19","author":"G\u00f6koglu","year":"2023","journal-title":"J Cancer Res Ther"},{"key":"10.25259\/SNI_757_2025\/ref-6","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1097\/RLU.0000000000004328","article-title":"Isolated cerebellar metastasis from papillary thyroid carcinoma detected on SPECT\/CT","volume":"47","author":"Gupta","year":"2022","journal-title":"Clin Nucl Med"},{"key":"10.25259\/SNI_757_2025\/ref-7","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1186\/s40064-016-2551-4","article-title":"Metastatic cerebellar tumor of papillary thyroid carcinoma mimicking cerebellar hemangioblastoma","volume":"5","author":"Ideguchi","year":"2016","journal-title":"SpringerPlus"},{"key":"10.25259\/SNI_757_2025\/ref-8","first-page":"234","article-title":"Hemorrhagic cerebellar metastasis from papillary thyroid carcinoma","volume":"15","author":"Lin","year":"1999","journal-title":"Kaohsiung J Med Sci"},{"key":"10.25259\/SNI_757_2025\/ref-9","first-page":"419","article-title":"Brain metastases from thyroid carcinoma: A review of 21 cases","volume":"37","author":"Muresan","year":"2014","journal-title":"J Endocrinol Invest"},{"key":"10.25259\/SNI_757_2025\/ref-10","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1089\/thy.2011.0535","article-title":"The impact of distant metastases at presentation on prognosis in patients with differentiated carcinoma of the thyroid gland","volume":"22","author":"Nixon","year":"2012","journal-title":"Thyroid"},{"key":"10.25259\/SNI_757_2025\/ref-11","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1089\/thy.1998.8.327","article-title":"Solitary cerebellar metastasis from papillary thyroid carcinoma: A case report","volume":"8","author":"Pacak","year":"1998","journal-title":"Thyroid"},{"key":"10.25259\/SNI_757_2025\/ref-12","first-page":"15","article-title":"The cystic cerebellar lesion: A differential diagnostic problem","volume":"151","author":"Rachinger","year":"2009","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_757_2025\/ref-13","doi-asserted-by":"crossref","first-page":"7180","DOI":"10.4076\/1757-1626-2-7180","article-title":"Brain metastasis from thyroid adenomatous nodules or an encapsulated thyroid follicular tumor without capsular and vascular invasion: A case report","volume":"2","author":"Terada","year":"2009","journal-title":"Cases J"},{"key":"10.25259\/SNI_757_2025\/ref-14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21608\/ejentas.2021.24293.1175","article-title":"A rare metastatic follicular thyroid carcinoma masquerading as primary sinonasal carcinoma presentation with unusual orbit, skull base and brain metastases","volume":"22","author":"Tong","year":"2021","journal-title":"Egypt J Ear Nose Throat Allied Sci"},{"key":"10.25259\/SNI_757_2025\/ref-15","doi-asserted-by":"crossref","first-page":"e240093","DOI":"10.1530\/ETJ-24-0093","article-title":"Incidence and gender difference of brain metastases in newly diagnosed follicular thyroid cancer patients","volume":"13","author":"Zhang","year":"2024","journal-title":"Eur Thyroid J"},{"key":"10.25259\/SNI_757_2025\/ref-16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13000-019-0924-z","article-title":"Causes of misdiagnoses by thyroid fine-needle aspiration cytology (FNAC): Our experience and a systematic review","volume":"15","author":"Zhu","year":"2020","journal-title":"Diagn Pathol"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/isolated-cerebellar-metastasis-as-the-initial-presentation-of-follicular-thyroid-carcinoma-a-rare-neurosurgical-encounter\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/isolated-cerebellar-metastasis-as-the-initial-presentation-of-follicular-thyroid-carcinoma-a-rare-neurosurgical-encounter\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:27:55Z","timestamp":1767349675000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/isolated-cerebellar-metastasis-as-the-initial-presentation-of-follicular-thyroid-carcinoma-a-rare-neurosurgical-encounter\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,2]]},"references-count":16,"alternative-id":["10.25259\/SNI_757_2025"],"URL":"https:\/\/doi.org\/10.25259\/sni_757_2025","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,2]]},"article-number":"7"}}