{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T08:13:14Z","timestamp":1788509594645,"version":"build-2803163510"},"reference-count":12,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Chronic low back pain is a highly prevalent condition; however, primary spinal malignancies, though rare, carry critical clinical implications. Chondrosarcoma is a slow-growing malignant bone tumor, with spinal involvement accounting for <10% of cases. Tumors originating from the posterior vertebral elements, particularly the transverse process, are exceedingly uncommon and frequently result in delayed diagnosis due to their indolent clinical course.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n We present a 51-year-old male with a 5-year history of intermittent low back pain who developed a progressively noticeable lumbar mass. Advanced imaging demonstrated a heterogeneous, partially calcified lesion arising from the left L5 transverse process with extension into the adjacent paraspinal soft tissues. Histopathological evaluation confirmed a Grade 1 chondrosarcoma. The patient underwent en bloc resection of the tumor, including the involved transverse process, through a posterior approach under intraoperative neuromonitoring. Postoperative imaging showed no radiological evidence of residual tumor; no adjuvant therapy was administered. At the 1-year follow-up, the patient remained asymptomatic with no radiological evidence of recurrence.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Primary chondrosarcoma of the lumbar transverse process represents an exceptionally rare entity that should be considered in patients presenting with long-standing back pain accompanied by a palpable or fixed paraspinal mass or other suspicious imaging findings. Complete\n en bloc<\/jats:italic>\n surgical resection remains the cornerstone of treatment and was associated with a favorable early outcome in this case, though long-term surveillance is essential, given the potential for late recurrence.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_758_2026","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T07:28:10Z","timestamp":1788506890000},"page":"505","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary chondrosarcoma arising from the L5 transverse process: A rare cause of chronic low back pain"],"prefix":"10.25259","volume":"17","author":[{"given":"Mert","family":"Arslan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"10.25259\/SNI_758_2026\/ref-1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4184\/asj.2012.6.4.279","article-title":"Chondrosarcoma of the spinous process: A rare presentation","volume":"6","author":"Arockiaraj","year":"2012","journal-title":"Asian Spine J"},{"key":"10.25259\/SNI_758_2026\/ref-2","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1002\/1097-0142(197708)40:2<818::AID-CNCR2820400234>3.0.CO;2-B","article-title":"Prognostic factors in chondrosarcoma of bone: A clinicopathologic analysis with emphasis on histologic grading","volume":"40","author":"Evans","year":"1977","journal-title":"Cancer"},{"key":"10.25259\/SNI_758_2026\/ref-3","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/00129039-200609000-00013","article-title":"Diagnostic significance of immunohistochemical detection of growth factors in benign and malignant cartilaginous tumors","volume":"14","author":"Falcone","year":"2006","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.25259\/SNI_758_2026\/ref-4","doi-asserted-by":"crossref","first-page":"350","DOI":"10.2519\/jospt.2020.9971","article-title":"International framework for red flags for potential serious spinal pathologies","volume":"50","author":"Finucane","year":"2020","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.25259\/SNI_758_2026\/ref-5","article-title":"Pathology and Genetics of Tumours of Soft Tissue and Bone","author":"Fletcher","year":"2002"},{"key":"10.25259\/SNI_758_2026\/ref-6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1746-1596-1-39","article-title":"Chondrosarcoma of the spine: A rare case with unusual presentation","volume":"1","author":"Panelos","year":"2006","journal-title":"Diagn Pathol"},{"key":"10.25259\/SNI_758_2026\/ref-7","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1007\/s00280-017-3436-0","article-title":"Malignant bone tumors (other than Ewing\u2019s): Clinical practice guidelines for diagnosis, treatment and follow-up by the Spanish Group for research on sarcomas (GEIS)","volume":"80","author":"Redondo","year":"2017","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.25259\/SNI_758_2026\/ref-8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/s11864-009-0088-2","article-title":"The clinical management of chondrosarcoma","volume":"10","author":"Riedel","year":"2009","journal-title":"Curr Treat Options Oncol"},{"key":"10.25259\/SNI_758_2026\/ref-9","first-page":"154","article-title":"Chondrosarcoma of the spine: A series of 16 cases and a review of the literature","volume":"31","author":"Strike","year":"2011","journal-title":"Iowa Orthop J"},{"key":"10.25259\/SNI_758_2026\/ref-10","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1007\/s00256-012-1405-6","article-title":"Malignant degeneration of a lumbar osteochondroma into a chondrosarcoma which mimicked a large retroperitoneal mass","volume":"41","author":"Strovski","year":"2012","journal-title":"Skeletal Radiol"},{"key":"10.25259\/SNI_758_2026\/ref-11","doi-asserted-by":"crossref","first-page":"553","DOI":"10.5435\/JAAOS-D-20-01188","article-title":"Chondrosarcoma","volume":"29","author":"Weinschenk","year":"2021","journal-title":"J Am Acad Orthop Surg"},{"key":"10.25259\/SNI_758_2026\/ref-12","doi-asserted-by":"crossref","first-page":"299","DOI":"10.21037\/atm.2020.02.175","article-title":"Global low back pain prevalence and years lived with disability from 1990 to 2017: Estimates from the global burden of disease study 2017","volume":"8","author":"Wu","year":"2020","journal-title":"Ann Transl Med"}],"container-title":["Surgical Neurology 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