{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:28:17Z","timestamp":1793028497300,"version":"4.5.0"},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p><jats:italic>Nocardia<\/jats:italic> is an aerobic Gram-negative bacillus belonging to actinomycetes and has been reported to be an infectious disease in healthy individuals. However, more than 60% have some underlying illnesses and are said to be opportunistic infections.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>The case was a 69-year-old man who had been on long-term steroids for systemic lupus erythematosus. He developed with nausea and gait disturbance and was suspected of having a brain abscess by imaging. Abscess drainage detects actinomycetes that appear to belong to the genus <jats:italic>Nocardia<\/jats:italic> and brain abscess by <jats:italic>Nocardia thailandica<\/jats:italic> using matrix-assisted laser desorption\/ionization time-of-flight mass analysis (MALDITOFMS) I was diagnosed. He died during the course of the treatment, and his organs did not detect his <jats:italic>N. thailandica<\/jats:italic> at necropsy, so he concluded that bacterial death from long-term administration of antibiotics was the cause of death.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p><jats:italic>N. thailandica<\/jats:italic> is a very rare bacterium belonging to <jats:italic>Nocardia asteroides<\/jats:italic> and is said to easily form brain lesions. In immunocompromised patients, prophylaxis with antibiotics and detailed examination of lung lesions for surveillance were considered necessary. This paper is the first report of a brain abscess caused by <jats:italic>N. thailandica<\/jats:italic>, including a review of the literature.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_78_2022","type":"journal-article","created":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T07:28:49Z","timestamp":1649402929000},"page":"126","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Brain abscess caused by <i>Nocardia thailandica<\/i> infection in systemic lupus erythematosus patient with steroid therapy"],"prefix":"10.25259","volume":"13","author":[{"given":"Ryokichi","family":"Yagi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki City, Osaka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukimasa","family":"Ooi","sequence":"additional","affiliation":[{"name":"Department of Infection Control and Prevention, Osaka Medical and Pharmaceutical University, Takatsuki City, Osaka, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naosuke","family":"Nonoguchi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki City, Osaka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Wanibuchi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki City, Osaka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,4,8]]},"reference":[{"key":"10.25259\/SNI_78_2022\/ref-1","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1093\/infdis\/134.3.286","article-title":"Nocardial infections in the United States, 1972-1974","volume":"134","author":"Beaman","year":"1976","journal-title":"J Infect Dis"},{"key":"10.25259\/SNI_78_2022\/ref-2","doi-asserted-by":"crossref","first-page":"7843","DOI":"10.1093\/nar\/17.19.7843","article-title":"Isolation and direct complete nucleotide determination of entire genes. 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Nov., isolated from patients in Japan","volume":"48","author":"Kageyama","year":"2004","journal-title":"Microbiol Immunol"},{"key":"10.25259\/SNI_78_2022\/ref-6","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.resinv.2013.09.004","article-title":"Pulmonary nocardiosis: A clinical analysis of 59 cases","volume":"52","author":"Kurahara","year":"2014","journal-title":"Respir Investig"},{"key":"10.25259\/SNI_78_2022\/ref-7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S0303-8467(01)00201-3","article-title":"Primary brain abscess with Nocardia farcinica in an immunocompetent patient","volume":"104","author":"Malincarne","year":"2002","journal-title":"Clin Neurol Neurosurg"},{"key":"10.25259\/SNI_78_2022\/ref-8","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1227\/00006123-199410000-00007","article-title":"Nocardial brain abscess: Treatment strategies and factors influencing outcome","volume":"35","author":"Mamelak","year":"1994","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_78_2022\/ref-9","first-page":"218","article-title":"Mandell, Douglas, and Bennett\u2019s principles and practice of infectious diseases 7th edition","volume-title":"Sex Health","volume":"7","author":"McBride","year":"2010"},{"key":"10.25259\/SNI_78_2022\/ref-10","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/0002-9343(57)90023-2","article-title":"Fungus infections associated with antibiotic and steroid therapy","volume":"22","author":"Torack","year":"1957","journal-title":"Am J Med"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/brain-abscess-caused-by-nocardia-thailandica-infection-in-systemic-lupus-erythematosus-patient-with-steroid-therapy\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/brain-abscess-caused-by-nocardia-thailandica-infection-in-systemic-lupus-erythematosus-patient-with-steroid-therapy\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T07:28:56Z","timestamp":1649402936000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/brain-abscess-caused-by-nocardia-thailandica-infection-in-systemic-lupus-erythematosus-patient-with-steroid-therapy\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,8]]},"references-count":10,"alternative-id":["10.25259\/SNI_78_2022"],"URL":"https:\/\/doi.org\/10.25259\/sni_78_2022","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,8]]},"article-number":"126"}}